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'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''
{{Desmoid tumor}}
{{CMG}} {{AE}} {{S.M.}}, {{Faizan}}


{{CMG}}
{{SK}} Aggressive fibromatosis, Deep musculoaponeurotic fibromatosis, Deep fibromatosis, Familial infiltrative fibromatosis, Hereditary Desmoid tumor, Musculoaponeurotic fibromatosis, Nonmetastasizing fibrosarcoma, Fibromatosis of soft tissue, Grade I fibromatosis, Well-differentiated non-metastasizing fibromatosis
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==[[Desmoid tumor overview|Overview]]==


==Overview==
==[[Desmoid tumor historical perspective|Historical Perspective]]==
A '''desmoid tumor''' (sometimes referred to as ''aggressive fibromatosis'') is a rare (3 per million population) [[tumor]] that may or may not be part of a [[genetics|genetic]] [[syndrome]] such as [[familial adenomatous polyposis]] (FAP).


==Classification==
==[[Desmoid tumor classification|Classification]]==
Desmoid tumors may be classified as extra-[[human abdomen|abdominal]], [[layers of the abdominal wall|abdominal wall]], or intra-abdominal (the last is more common in patients with FAP). It is thought that the lesions may develop in relation to [[estrogen]] levels or [[physical trauma|trauma]]/[[surgery|operations]].


==Pathophysiology==
==[[Desmoid tumor pathophysiology|Pathophysiology]]==
===Microscopic Pathology===
 
Histologically, Desmoid tumors resemble [[grading (tumors)|low-grade]] [[fibrosarcoma]]s, but they are very [[infiltration (medicine)|infiltrative]] and tend to recur even after complete resection (systemic [[metastasis]] is rare).
==[[Desmoid tumor causes|Causes]]==
 
==[[Desmoid tumor differential diagnosis|Differentiating desmoid tumor from other Diseases]]==
 
==[[Desmoid tumor epidemiology and demographics|Epidemiology and Demographics]]==
 
==[[Desmoid tumor risk factors|Risk Factors]]==
 
==[[Desmoid tumor natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
 
==Diagnosis==
[[Desmoid tumor diagnostic study of choice|Diagnostic study of choice]] | [[Desmoid tumor history and symptoms|History and Symptoms]] | [[Desmoid tumor physical examination|Physical Examination]] |[[Desmoid tumor laboratory tests|Laboratory Findings]] | [[Desmoid tumor CT|CT]] | [[Desmoid tumor MRI|MRI]] | [[Desmoid tumor other imaging findings|Other Imaging Findings]] | [[Desmoid tumor other diagnostic studies|Other Diagnostic Studies]]


==Treatment==
==Treatment==
===Medical Therapy===
[[Desmoid tumor medical therapy|Medical Therapy]] | [[Desmoid tumor surgery|Surgery]] | [[Desmoid tumor cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Desmoid tumor future or investigational therapies|Future or Investigational Therapies]]
Treatment may consist of watching and waiting, complete [[surgery|surgical]] removal, [[radiation therapy]], [[antiestrogens]] and [[non-steroidal anti-inflammatory drug|NSAIDs]], or [[chemotherapy]].


==External links==
==Case Studies==
*[http://www.dtrf.org Desmoid Tumor Research Foundation]
[[Desmoid tumor case study one|Case #1]]


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Latest revision as of 20:46, 19 August 2020

For patient information click here

Desmoid tumor Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Desmoid tumor from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

CT

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sara Mohsin, M.D.[2], Faizan Sheraz, M.D. [3]

Synonyms and keywords: Aggressive fibromatosis, Deep musculoaponeurotic fibromatosis, Deep fibromatosis, Familial infiltrative fibromatosis, Hereditary Desmoid tumor, Musculoaponeurotic fibromatosis, Nonmetastasizing fibrosarcoma, Fibromatosis of soft tissue, Grade I fibromatosis, Well-differentiated non-metastasizing fibromatosis

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating desmoid tumor from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

Diagnostic study of choice | History and Symptoms | Physical Examination |Laboratory Findings | CT | MRI | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1

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