Hypogonadism causes: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Hypogonadism}} | {{Hypogonadism}} | ||
{{CMG}} | {{CMG}} {{AE}} {{ADI}} {{LRO}} | ||
==Overview== | ==Overview== | ||
Hypogonadism is commonly caused by [[congenital]], acquired [[genetic]] and [[endocrinology|endocrinological]] conditions. Life threatening causes may include malignancies and must take in to consideration during patient approach.<ref>Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016</ref><ref>Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X</ref> | |||
==Causes == | |||
<div style="-webkit-user-select: none;"> | |||
===Life Threatening Causes=== | |||
Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated. The following diseases are life threatening causes of hypogonadism: | |||
*[[Astrocytoma]] | |||
*[[Chronic renal failure]] | |||
*[[Renal cell carcinoma|Papillary renal cell carcinoma]] | |||
*Postinfectious lesions of the [[CNS|central nervous system (CNS)]] | |||
*Ureter cancer | |||
*Urinary system cancer | |||
*[[Wilms tumor ]] | |||
*[[Infective endocarditis]] | |||
===Common Causes=== | |||
*[[Anorchidism]] | |||
*[[Chemotherapy]] | |||
*[[Cryptorchidism]] | |||
*[[FSH]] beta subunit mutation (follicle stimulating hormone) | |||
*[[FSH]] receptor mutation | |||
*[[Klinefelter Syndrome]] | |||
*[[LH]] (luteinizing hormone) beta subunit mutation | |||
*[[LH]] receptor mutation | |||
*[[LH]] resistance | |||
*[[Radiation therapy]] | |||
*[[Sertoli-cell]]-only syndrome | |||
*[[Testicular]] biosynthetic defects | |||
* [[Autoimmune]] [[oophoritis]] | |||
* [[Chemotherapy]] | |||
* Familial and sporadic XX gonadal [[dysgenesis]] and its variants | |||
* Familial and sporadic XY gonadal dysgenesis and its variants | |||
* [[FSH]] beta subunit mutation (follicle stimulating hormone) | |||
* [[FSH]] receptor mutation | |||
* [[Galactosemia]] | |||
* [[Glycoprotein]] syndrome type 1 | |||
* LH (luteinizing hormone) beta subunit mutation | |||
* LH/[[Ddx:Human Chorionic Gonadotropin|human chorionic gonadotropin]] resistance | |||
* LH receptor mutation | |||
* [[Noonan Syndrome]] | |||
* Premature [[menopause]] | |||
* [[Polycystic ovarian disease]] | |||
* [[Radiation therapy]] | |||
* Resistant [[ovary]] | |||
* [[Turner Syndrome]] | |||
* [[Astrocytoma]] | |||
* [[Bardet-Biedl Syndrome]] | |||
* Congenital adrenal hypoplasia | |||
* Congenital hypogonadotropic hypogonadism | |||
* [[Craniofacial]] anomalies | |||
* [[Craniopharyngioma]] | |||
* Exercise-induced amenorrhea | |||
* Functional gonadotropin deficiency | |||
* [[Gaucher Disease]] | |||
* Germinoma | |||
* Head trauma | |||
* [[Ddx:Prolactin|Hyperprolactinemia]] | |||
* Hypothalamic glioma | |||
* Isolated FSH deficiency | |||
* Isolated LH deficiency | |||
* [[Kallmann Syndrome]] | |||
* Langerhans histiocytosis | |||
* [[Laurence-Moon Syndrome]] | |||
* Marijuana use | |||
* Optic glioma | |||
* Other germ cell tumors | |||
* Pituitary tumor | |||
* Postinfectious lesions of the central nervous system (CNS) | |||
* [[Prader-Willi Syndrome]] | |||
* Radiation therapy | |||
* Vascular abnormalities of the CNS | |||
===Causes by Organ System=== | |||
{| style="width:80%; height:100px" border="1" | |||
| style="width:25%" bgcolor="LightSteelBlue" ; border="1" |'''Cardiovascular''' | |||
| style="width:75%" bgcolor="Beige" ; border="1" | [[Alström syndrome]], [[Amyloidosis]], [[Cardiofaciocutaneous syndrome]], [[Vascular abnormalities of the cns]] | |||
|- | |||
| bgcolor="LightSteelBlue" | '''Chemical/Poisoning''' | |||
| bgcolor="Beige" | [[Alcohol]], [[Alkylating agents]], [[Cytotoxic therapeutic agents]], [[Environmental toxins]], [[Ethanol]], [[Toxins]] | |||
|- | |||
|- bgcolor="LightSteelBlue" | |||
| '''Dental''' | |||
| bgcolor="Beige" | [[Jaffe-campanacci syndrome]], [[Lepromatous leprosy]] | |||
|- | |||
|- bgcolor="LightSteelBlue" | |||
| '''Dermatologic''' | |||
| bgcolor="Beige" | No underlying causes | |||
|- | |||
|- bgcolor="LightSteelBlue" | |||
| '''Drug Side Effect''' | |||
| bgcolor="Beige" | [[Antiandrogens]], [[Ketoconazole]], [[Marijuana use]], [[Opioids]] | |||
|- | |||
|- bgcolor="LightSteelBlue" | |||
| '''Ear Nose Throat''' | |||
| bgcolor="Beige" | No underlying causes | |||
|- | |||
|- bgcolor="LightSteelBlue" | |||
| '''Endocrine''' | |||
| bgcolor="Beige" | [[Adiposogenital dystrophy]], [[Adrenal hypoplasia]], [[Autoimmune polyendocrine syndrome type 2]], [[Combined pituitary hormone deficiency ]] , [[Disorders of androgen synthesis]], [[Functional gonadotropin deficiency]], [[Glucocorticoids]], [[Glycoprotein syndrome type 1]], [[Gonadal dysgenesis ]] , [[Growth hormone secreting pituitary adenoma]], [[Hyperprolactinemia]], [[Hypogonadic hypogonadism]], [[Hypopituitarism]], [[Hypothalamic glioma]], [[Panhypopituitarism]], [[Pituitary tumor]], [[Poems syndrome]], [[Polycystic ovarian disease]], [[Proprotein convertase 1/3 deficiency]], [[Pseudohypoparathyroidism type 1a]], [[Swyer's syndrome]], [[Testicular biosynthetic defects]] | |||
|- | |||
|- bgcolor="LightSteelBlue" | |||
| '''Environmental''' | |||
| bgcolor="Beige" | No underlying causes | |||
|- | |||
|- bgcolor="LightSteelBlue" | |||
| '''Gastroenterologic''' | |||
| bgcolor="Beige" | [[Hepatic cirrhosis]] | |||
|- | |||
|- bgcolor="LightSteelBlue" | |||
| '''Genetic''' | |||
| bgcolor="Beige" | [[17α-hydroxylase deficiency]], [[17β-hydroxysteroid dehydrogenase iii deficiency]], [[20-lyase deficiency]], [[48, xxxy aneuploidy]], [[48, xxyy aneuploidy]], [[4h syndrome]], [[Acrocephalopolysyndactyly type 2]], [[Alström syndrome]], [[Aromatase deficiency]], [[Autoimmune oophoritis]], [[Bardet-biedl syndrome]], [[Belgian type mental retardation]], [[Blepharophimosis syndrome]], [[Borjeson-forssman-lehmann syndrome]], [[Boucher-neuhäuser syndrome]], [[Cardiofaciocutaneous syndrome]], [[Ccfdn syndrome]], [[Charge syndrome]], [[Congenital adrenal hypoplasia]], [[Craniofacial anomalies]], [[Craniopharyngioma]], [[Cryptorchidism]], [[Didmoad syndrome]], [[Dystrophia myotonica type 2]], [[Fsh receptor deficiency]], [[Fsh beta subunit mutation (follicle stimulating hormone)]], [[Fsh receptor mutation]], [[Galactose-1-phosphate uridyltransferase deficiency]], [[Galactosemia]], [[Gaucher disease]], [[Gordon holmes syndrome]], [[Hartsfield syndrome]], [[Image syndrome]], [[Isolated fsh deficiency]], [[Isolated lh deficiency]], [[Jaffe-campanacci syndrome]], [[Kallmann syndrome]], [[Klinefelter syndrome]], [[Laurence-moon syndrome]], [[Leptin deficiency]], [[Lh (luteinizing hormone) beta subunit mutation]], [[Lh receptor mutation]], [[Lh resistance]], [[Lipoid congenital adrenal hyperplasia]], [[Malouf syndrome]], [[Marinesco-sjogren-garland syndrome]], [[Martsolf syndrome]], [[Mobius syndrome]], [[Mosaicism]], [[Myotonic dystrophy]], [[Noonan syndrome]], [[Prader-willi syndrome]], [[Proprotein convertase 1/3 deficiency]], [[Resistant ovary]], [[Rud syndrome]], [[Sertoli-cell-only syndrome]], [[Turner syndrome]], [[Woodhouse-sakati syndrome]], [[X-linked mental retardation-hypotonic facies syndrome]], [[Xx gonadal dysgenesis]] | |||
|- | |||
|- bgcolor="LightSteelBlue" | |||
| '''Hematologic''' | |||
| bgcolor="Beige" | [[Glycoprotein syndrome type 1]], [[Hemochromatosis]], [[Langerhans histiocytosis]], [[Leukoencephalopathy ]] , [[Zinc deficiency]] | |||
|- | |||
|- bgcolor="LightSteelBlue" | |||
| '''Iatrogenic''' | |||
| bgcolor="Beige" | [[Chemotherapy]], [[Opioids]], [[Orchitis]], [[Radiation therapy]], [[Surgery]] | |||
|- | |||
|- bgcolor="LightSteelBlue" | |||
| '''Infectious Disease''' | |||
| bgcolor="Beige" | [[Aids]], [[Infections]], [[Mumps]] | |||
|- | |||
|- bgcolor="LightSteelBlue" | |||
| '''Musculoskeletal/Orthopedic''' | |||
| bgcolor="Beige" | No underlying causes | |||
|- | |||
|- bgcolor="LightSteelBlue" | |||
| '''Neurologic''' | |||
| bgcolor="Beige" | [[Astrocytoma]], [[Belgian type mental retardation]], [[Craniopharyngioma]], [[Gordon holmes syndrome]], [[Poems syndrome]], [[Postinfectious lesions of the central nervous system (cns)]], [[Vascular abnormalities of the cns]] | |||
|- | |||
|- bgcolor="LightSteelBlue" | |||
| '''Nutritional/Metabolic''' | |||
| bgcolor="Beige" | [[Zinc deficiency]] | |||
|- | |||
|- bgcolor="LightSteelBlue" | |||
| '''Obstetric/Gynecologic''' | |||
| bgcolor="Beige" | [[Exercise-induced amenorrhea]], [[Ovarian resistance syndrome]], [[Ovarian torsion]], [[Polycystic ovarian disease]], [[Premature ovarian failure]], [[Premature menopause]], [[Resistant ovary]], [[Rud syndrome]], [[Suramin]], [[Swyer's syndrome]] | |||
|- | |||
|- bgcolor="LightSteelBlue" | |||
| '''Oncologic''' | |||
| bgcolor="Beige" | [[Astrocytoma]], [[Germinoma]], [[Growth hormone secreting pituitary adenoma]], [[Hypothalamic glioma]], [[Langerhans histiocytosis]], [[Optic glioma]], [[Other germ cell tumors]], [[Pituitary tumor]] | |||
|- | |||
|- bgcolor="LightSteelBlue" | |||
| '''Ophthalmologic''' | |||
| bgcolor="Beige" | [[Optic glioma]] | |||
|- | |||
|- bgcolor="LightSteelBlue" | |||
| '''Overdose/Toxicity''' | |||
| bgcolor="Beige" | [[Alcohol]] | |||
|- | |||
|- bgcolor="LightSteelBlue" | |||
| '''Psychiatric''' | |||
| bgcolor="Beige" | [[Anorexia nervosa]] | |||
|- | |||
|- bgcolor="LightSteelBlue" | |||
| '''Pulmonary''' | |||
| bgcolor="Beige" | No underlying causes | |||
|- | |||
|- bgcolor="LightSteelBlue" | |||
| '''Renal/Electrolyte''' | |||
| bgcolor="Beige" | [[Chronic renal failure]], [[Renal failure]] | |||
|- | |||
|- bgcolor="LightSteelBlue" | |||
| '''Rheumatology/Immunology/Allergy''' | |||
| bgcolor="Beige" | [[Amyloidosis]], [[Autoimmune damage]], [[Autoimmunity]], [[Chronic systemic illnesses]], [[Lepromatous leprosy]] | |||
|- | |||
|- bgcolor="LightSteelBlue" | |||
| '''Sexual''' | |||
| bgcolor="Beige" | [[Aids]], [[Epididymo-orchitis]], [[Germinoma]], [[Orchidectomy]], [[Suramin]] | |||
|- | |||
|- bgcolor="LightSteelBlue" | |||
| '''Trauma''' | |||
| bgcolor="Beige" | [[Head trauma]], [[Hepatic cirrhosis]], [[Ovarian torsion]], [[Testicular torsion]], [[Trauma]] | |||
|- | |||
|- bgcolor="LightSteelBlue" | |||
| '''Urologic''' | |||
| bgcolor="Beige" | [[Anorchia]], [[Anorchidism]], [[Congenital hypogonadotropic hypogonadism]], [[Cryptorchidism]], [[Disorders of androgen synthesis]], [[Epididymo-orchitis]], [[Gonadal dysgenesis ]] , [[Hypogonadic hypogonadism]], [[Orchitis]], [[Testicular torsion]], [[Varicocele]] | |||
|- | |||
|- bgcolor="LightSteelBlue" | |||
| '''Miscellaneous''' | |||
| bgcolor="Beige" | No underlying causes | |||
|- | |||
|} | |||
===Causes in Alphabetical Order=== | |||
{{columns-list| | |||
*[[17α-hydroxylase deficiency]] | |||
*[[17β-hydroxysteroid dehydrogenase iii deficiency]] | |||
*[[20-lyase deficiency]] | |||
*[[48, xxxy aneuploidy]] | |||
*[[48, xxyy aneuploidy]] | |||
*[[4h syndrome]] | |||
*[[Acrocephalopolysyndactyly type 2]] | |||
*[[Adiposogenital dystrophy]] | |||
*[[Adrenal hypoplasia]] | |||
*[[Aids]] | |||
*[[Alcohol]] | |||
*[[Alkylating agents]] | |||
*[[Alström syndrome]] | |||
*[[Amyloidosis]] | |||
*[[Anorchia]] | |||
*[[Anorchidism]] | |||
*[[Anorexia nervosa]] | |||
*[[Antiandrogens]] | |||
*[[Aromatase deficiency]] | |||
*[[Astrocytoma]] | |||
*[[Autoimmune damage]] | |||
*[[Autoimmune oophoritis]] | |||
*[[Autoimmune polyendocrine syndrome type 2]] | |||
*[[Autoimmunity]] | |||
*[[Bardet-biedl syndrome]] | |||
*[[Belgian type mental retardation]] | |||
*[[Blepharophimosis syndrome]] | |||
*[[Borjeson-forssman-lehmann syndrome]] | |||
*[[Boucher-neuhäuser syndrome]] | |||
*[[Cardiofaciocutaneous syndrome]] | |||
*[[Ccfdn syndrome]] | |||
*[[Charge syndrome]] | |||
*[[Chemotherapy]] | |||
*[[Chronic renal failure]] | |||
*[[Chronic systemic illnesses]] | |||
*[[Combined pituitary hormone deficiency ]] | |||
*[[Congenital adrenal hypoplasia]] | |||
*[[Congenital hypogonadotropic hypogonadism]] | |||
*[[Craniofacial anomalies]] | |||
*[[Craniopharyngioma]] | |||
*[[Cryptorchism]] | |||
*[[Cytotoxic therapeutic agents]] | |||
*[[Didmoad syndrome]] | |||
*[[Disorders of androgen synthesis]] | |||
*[[Dystrophia myotonica type 2]] | |||
*[[Environmental toxins]] | |||
*[[Epididymo-orchitis]] | |||
*[[Ethanol]] | |||
*[[Exercise-induced amenorrhea]] | |||
*[[Fsh receptor deficiency]] | |||
*[[Fsh beta subunit mutation (follicle stimulating hormone)]] | |||
*[[Fsh receptor mutation]] | |||
*[[Functional gonadotropin deficiency]] | |||
*[[Galactose-1-phosphate uridyltransferase deficiency]] | |||
*[[Galactosemia]] | |||
*[[Gaucher disease]] | |||
*[[Germinoma]] | |||
*[[Glucocorticoids]] | |||
*[[Glycoprotein syndrome type 1]] | |||
*[[Gonadal dysgenesis ]] | |||
*[[Gordon holmes syndrome]] | |||
*[[Growth hormone secreting pituitary adenoma]] | |||
*[[Hartsfield syndrome]] | |||
*[[Head trauma]] | |||
*[[Hemochromatosis]] | |||
*[[Hepatic cirrhosis]] | |||
*[[Hyperprolactinemia]] | |||
*[[Hypogonadic hypogonadism]] | |||
*[[Hypogonadotrophic hypogonadism]] | |||
*[[Hypopituitarism]] | |||
*[[Hypothalamic glioma]] | |||
*[[Idiopathic]] | |||
*[[Image syndrome]] | |||
*[[Infections]] | |||
*[[Isolated fsh deficiency]] | |||
*[[Isolated lh deficiency]] | |||
*[[Jaffe-campanacci syndrome]] | |||
*[[Kallmann syndrome]] | |||
*[[Ketoconazole]] | |||
*[[Klinefelter syndrome]] | |||
*[[Langerhans histiocytosis]] | |||
*[[Laurence-moon syndrome]] | |||
*[[Lepromatous leprosy]] | |||
*[[Leptin deficiency]] | |||
*[[Leukoencephalopathy ]] | |||
*[[Lh (luteinizing hormone) beta subunit mutation]] | |||
*[[Lh receptor mutation]] | |||
*[[Lh resistance]] | |||
*[[Lipoid congenital adrenal hyperplasia]] | |||
*[[Malouf syndrome]] | |||
*[[Marijuana use]] | |||
*[[Marinesco-sjogren-garland syndrome]] | |||
*[[Martsolf syndrome]] | |||
*[[Mobius syndrome]] | |||
*[[Mosaicism]] | |||
*[[Mumps]] | |||
*[[Myotonic dystrophy]] | |||
*[[Noonan syndrome]] | |||
*[[Opioids]] | |||
*[[Optic glioma]] | |||
*[[Orchidectomy]] | |||
*[[Orchitis]] | |||
*[[Other germ cell tumors]] | |||
*[[Ovarian resistance syndrome]] | |||
*[[Ovarian torsion]] | |||
*[[Panhypopituitarism]] | |||
*[[Pituitary tumor]] | |||
*[[Poems syndrome]] | |||
*[[Polycystic ovarian disease]] | |||
*[[Postinfectious lesions of the central nervous system (cns)]] | |||
*[[Prader-willi syndrome]] | |||
*[[Premature ovarian failure]] | |||
*[[Premature menopause]] | |||
*[[Proprotein convertase 1/3 deficiency]] | |||
*[[Pseudohypoparathyroidism type 1a]] | |||
*[[Radiation therapy]] | |||
*[[Radiotherapy]] | |||
*[[Renal failure]] | |||
*[[Resistant ovary]] | |||
*[[Rud syndrome]] | |||
*[[Sertoli-cell-only syndrome]] | |||
*[[Suramin]] | |||
*[[Surgery]] | |||
*[[Swyer's syndrome]] | |||
*[[Testicular biosynthetic defects]] | |||
*[[Testicular torsion]] | |||
*[[Toxins]] | |||
*[[Trauma]] | |||
*[[Turner syndrome]] | |||
*[[Varicocele]] | |||
*[[Vascular abnormalities of the cns]] | |||
*[[Woodhouse-sakati syndrome]] | |||
*[[X-linked mental retardation-hypotonic facies syndrome]] | |||
*[[Xx gonadal dysgenesis]] | |||
*[[Zinc deficiency]] | |||
*[[Hemophilia ]] | |||
*[[Henoch-schonlein purpura ]] | |||
*[[Hepatitis a ]] | |||
*[[Hepatitis b ]] | |||
*[[Hepatitis c ]] | |||
*[[Hepatorenal tyrosinemia]] | |||
*[[Hereditary hemorrhagic telangiectasia ]] | |||
*[[Hereditary leiomyomatosis ]] | |||
*[[Herns syndrome ]] | |||
*[[Honeymoon bladder ]] | |||
*[[Hypercalciuria]] | |||
*[[Hypertension ]] | |||
*[[Hypocomplementemic urticarial vasculitis]] | |||
*[[Idarubicin]] | |||
*[[Iga nephropathy ]] | |||
*[[Immune thrombocytopenic purpura ]] | |||
*[[Indandione rodenticide poisoning ]] | |||
*[[Infective endocarditis]] | |||
*[[Interstitial nephritis ]] | |||
*[[Jaundice ]] | |||
*[[Juniper tar poisoning ]] | |||
*[[Kidney cancer ]] | |||
*[[Kidney stones ]] | |||
*[[Klerat rodenticide poisoning ]] | |||
*[[Lactate dehydrogenase deficiency ]] | |||
*[[Lecithin-cholesterol acyltransferase deficiency]] | |||
*[[Leiomyomatosis of esophagus]] | |||
*[[Leucinosis ]] | |||
*[[Leukocytoclastic angiitis ]] | |||
*[[Liver cancer ]] | |||
*[[Machupo virus ]] | |||
*[[Malaria ]] | |||
*[[Malignant rhabdoid tumors ]] | |||
*[[Maple syrup urine disease]] | |||
*[[Matikus rodenticide poisoning ]] | |||
*[[Medullary sponge kidney ]] | |||
*[[Meier-blumberg-imahorn syndrome ]] | |||
*[[Melanoma]] | |||
*[[Membranous nephropathy]] | |||
*[[Mepacrine]] | |||
*[[Methaemoglobinaemia]] | |||
*[[Metronidazole]] | |||
*[[Milky urine]] | |||
*[[Mitoxantrone]] | |||
*[[Monosodium methanarsenate ]] | |||
*[[Mouser rodenticide poisoninge]] | |||
*[[Myoglobinuria]] | |||
*[[Nail-patella syndrome ]] | |||
*[[Naked brimcap poisoning ]] | |||
*[[Naphthalene ]] | |||
*[[Nefopam]] | |||
*[[Neoplastic porphyria tarda ]] | |||
*[[Nephritis ]] | |||
*[[Nephrocalcinosis ]] | |||
*[[Nephropathy]] | |||
*[[Nephrosis ]] | |||
*[[Nitrates ]] | |||
*[[Norum disease]] | |||
*[[Obstructive jaundice]] | |||
*[[Oncocytoma]] | |||
*[[Oral contraceptives]] | |||
*[[Orchitis ]] | |||
*[[Oxalosis ]] | |||
*[[Oxamniquine]] | |||
*[[Papillary renal cell carcinoma ]] | |||
*[[Paragonimiases ]] | |||
*[[Parkinson's disease]] | |||
*[[Pelvic fracture ]] | |||
*[[Pelvic lipomatosis ]] | |||
*[[Penis cancer ]] | |||
*[[Penis conditions ]] | |||
*[[Penis tourniquet syndrome ]] | |||
*[[Pennyroyal oil]] | |||
*[[Peppermint oil ]] | |||
*[[Petroleum distillates ]] | |||
*[[Phenazopyridine]] | |||
*[[Phenol ]] | |||
*[[Phenolphthalein]] | |||
*[[Phensuximide]] | |||
*[[Phosphine ]] | |||
*[[Phyllodes tumor of the prostate ]] | |||
*[[Pierson syndrome ]] | |||
*[[Pindone rodenticide poisoning ]] | |||
*[[Pixantrone]] | |||
*[[Polycystic kidney disease]] | |||
*[[Porphyria ]] | |||
*[[Precalicial canalicular ectasia]] | |||
*[[Prostate cancer ]] | |||
*[[Prostatic abscess ]] | |||
*[[Prostatitis ]] | |||
*[[Pyelonephritis ]] | |||
*[[Quebec platelet disorder]] | |||
*[[Ratak plus rodenticide poisoning]] | |||
*[[Reflux nephropathy ]] | |||
*[[Reiter’s syndrome ]] | |||
*[[Renal abscess ]] | |||
*[[Renal cancer ]] | |||
*[[Renal colic ]] | |||
*[[Renal failure]] | |||
*[[Renal hypertension]] | |||
*[[Renal mucormycosis ]] | |||
*[[Renal nutcracker syndrome ]] | |||
*[[Renal zygmycosis ]] | |||
*[[Renovascular hypertension ]] | |||
*[[Rhabdoid tumor ]] | |||
*[[Rhabdomyolysis]] | |||
*[[Rhubarb ]] | |||
*[[Rifabutin]] | |||
*[[Rifampicin]] | |||
*[[Rodend rodenticide poisoning ]] | |||
*[[Rue]] | |||
*[[Salcedo syndrome ]] | |||
*[[Sarcoma botryoides ]] | |||
*[[Schistosomiasis ]] | |||
*[[Senna ]] | |||
*[[Southworth symptom complex]] | |||
*[[Spirochetes disease ]] | |||
*[[Stones ]] | |||
*[[Stuart factor deficiency]] | |||
*[[Sulphasalazine]] | |||
*[[Talon rodenticide poisoning ]] | |||
*[[Thalassemia ]] | |||
*[[Thrombasthenia ]] | |||
*[[Thrombocytopathy ]] | |||
*[[Thrombocytopenia]] | |||
*[[Thrombocytopenic purpura]] | |||
*[[Torulopsis ]] | |||
*[[Toxic epidermal necrolysis ]] | |||
*[[Toxic mushrooms ]] | |||
*[[Transitional cell carcinoma]] | |||
*[[Trichosporin infection ]] | |||
*[[Tuberculosis ]] | |||
*[[Turpentine oil ]] | |||
*[[Urachal cancer ]] | |||
*[[Urachal cyst ]] | |||
*[[Urban schosser spohn syndrome ]] | |||
*[[Ureter cancer ]] | |||
*[[Urethral cancer ]] | |||
*[[Urinary disorders ]] | |||
*[[Urinary stones ]] | |||
*[[Urinary system cancer ]] | |||
*[[Urinary tract infections ]] | |||
*[[Urod-related porphyria cutanea tarda]] | |||
*[[Vasculitis hypersensitivity ]] | |||
*[[Vasculitis ]] | |||
*[[Volak rodenticide poisoning ]] | |||
*[[Volid rodenticide poisoning ]] | |||
*[[Wegener's granulomatosis ]] | |||
*[[Weil syndrome ]] | |||
*[[Wilms tumor ]] | |||
*[[Wilson's disease ]] | |||
*[[Xanthic urolithiasis ]] | |||
*[[Xanthine oxydase deficiency ]] | |||
*[[Xanthinuria]] | |||
*[[Yellow fever ]] | |||
}} | |||
</div> | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
[[Category:Endocrinology]] | [[Category:Endocrinology]] | ||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Urologic Surgery]] | [[Category:Urologic Surgery]] | ||
[[Category:Gynecology]] | [[Category:Gynecology]] |
Latest revision as of 21:20, 10 January 2020
Hypogonadism Microchapters |
Diagnosis |
---|
Treatment |
Case Studies |
Hypogonadism causes On the Web |
American Roentgen Ray Society Images of Hypogonadism causes |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2] Luke Rusowicz-Orazem, B.S.
Overview
Hypogonadism is commonly caused by congenital, acquired genetic and endocrinological conditions. Life threatening causes may include malignancies and must take in to consideration during patient approach.[1][2]
Causes
Life Threatening Causes
Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated. The following diseases are life threatening causes of hypogonadism:
- Astrocytoma
- Chronic renal failure
- Papillary renal cell carcinoma
- Postinfectious lesions of the central nervous system (CNS)
- Ureter cancer
- Urinary system cancer
- Wilms tumor
- Infective endocarditis
Common Causes
- Anorchidism
- Chemotherapy
- Cryptorchidism
- FSH beta subunit mutation (follicle stimulating hormone)
- FSH receptor mutation
- Klinefelter Syndrome
- LH (luteinizing hormone) beta subunit mutation
- LH receptor mutation
- LH resistance
- Radiation therapy
- Sertoli-cell-only syndrome
- Testicular biosynthetic defects
- Autoimmune oophoritis
- Chemotherapy
- Familial and sporadic XX gonadal dysgenesis and its variants
- Familial and sporadic XY gonadal dysgenesis and its variants
- FSH beta subunit mutation (follicle stimulating hormone)
- FSH receptor mutation
- Galactosemia
- Glycoprotein syndrome type 1
- LH (luteinizing hormone) beta subunit mutation
- LH/human chorionic gonadotropin resistance
- LH receptor mutation
- Noonan Syndrome
- Premature menopause
- Polycystic ovarian disease
- Radiation therapy
- Resistant ovary
- Turner Syndrome
- Astrocytoma
- Bardet-Biedl Syndrome
- Congenital adrenal hypoplasia
- Congenital hypogonadotropic hypogonadism
- Craniofacial anomalies
- Craniopharyngioma
- Exercise-induced amenorrhea
- Functional gonadotropin deficiency
- Gaucher Disease
- Germinoma
- Head trauma
- Hyperprolactinemia
- Hypothalamic glioma
- Isolated FSH deficiency
- Isolated LH deficiency
- Kallmann Syndrome
- Langerhans histiocytosis
- Laurence-Moon Syndrome
- Marijuana use
- Optic glioma
- Other germ cell tumors
- Pituitary tumor
- Postinfectious lesions of the central nervous system (CNS)
- Prader-Willi Syndrome
- Radiation therapy
- Vascular abnormalities of the CNS
Causes by Organ System
Causes in Alphabetical Order
- 17α-hydroxylase deficiency
- 17β-hydroxysteroid dehydrogenase iii deficiency
- 20-lyase deficiency
- 48, xxxy aneuploidy
- 48, xxyy aneuploidy
- 4h syndrome
- Acrocephalopolysyndactyly type 2
- Adiposogenital dystrophy
- Adrenal hypoplasia
- Aids
- Alcohol
- Alkylating agents
- Alström syndrome
- Amyloidosis
- Anorchia
- Anorchidism
- Anorexia nervosa
- Antiandrogens
- Aromatase deficiency
- Astrocytoma
- Autoimmune damage
- Autoimmune oophoritis
- Autoimmune polyendocrine syndrome type 2
- Autoimmunity
- Bardet-biedl syndrome
- Belgian type mental retardation
- Blepharophimosis syndrome
- Borjeson-forssman-lehmann syndrome
- Boucher-neuhäuser syndrome
- Cardiofaciocutaneous syndrome
- Ccfdn syndrome
- Charge syndrome
- Chemotherapy
- Chronic renal failure
- Chronic systemic illnesses
- Combined pituitary hormone deficiency
- Congenital adrenal hypoplasia
- Congenital hypogonadotropic hypogonadism
- Craniofacial anomalies
- Craniopharyngioma
- Cryptorchism
- Cytotoxic therapeutic agents
- Didmoad syndrome
- Disorders of androgen synthesis
- Dystrophia myotonica type 2
- Environmental toxins
- Epididymo-orchitis
- Ethanol
- Exercise-induced amenorrhea
- Fsh receptor deficiency
- Fsh beta subunit mutation (follicle stimulating hormone)
- Fsh receptor mutation
- Functional gonadotropin deficiency
- Galactose-1-phosphate uridyltransferase deficiency
- Galactosemia
- Gaucher disease
- Germinoma
- Glucocorticoids
- Glycoprotein syndrome type 1
- Gonadal dysgenesis
- Gordon holmes syndrome
- Growth hormone secreting pituitary adenoma
- Hartsfield syndrome
- Head trauma
- Hemochromatosis
- Hepatic cirrhosis
- Hyperprolactinemia
- Hypogonadic hypogonadism
- Hypogonadotrophic hypogonadism
- Hypopituitarism
- Hypothalamic glioma
- Idiopathic
- Image syndrome
- Infections
- Isolated fsh deficiency
- Isolated lh deficiency
- Jaffe-campanacci syndrome
- Kallmann syndrome
- Ketoconazole
- Klinefelter syndrome
- Langerhans histiocytosis
- Laurence-moon syndrome
- Lepromatous leprosy
- Leptin deficiency
- Leukoencephalopathy
- Lh (luteinizing hormone) beta subunit mutation
- Lh receptor mutation
- Lh resistance
- Lipoid congenital adrenal hyperplasia
- Malouf syndrome
- Marijuana use
- Marinesco-sjogren-garland syndrome
- Martsolf syndrome
- Mobius syndrome
- Mosaicism
- Mumps
- Myotonic dystrophy
- Noonan syndrome
- Opioids
- Optic glioma
- Orchidectomy
- Orchitis
- Other germ cell tumors
- Ovarian resistance syndrome
- Ovarian torsion
- Panhypopituitarism
- Pituitary tumor
- Poems syndrome
- Polycystic ovarian disease
- Postinfectious lesions of the central nervous system (cns)
- Prader-willi syndrome
- Premature ovarian failure
- Premature menopause
- Proprotein convertase 1/3 deficiency
- Pseudohypoparathyroidism type 1a
- Radiation therapy
- Radiotherapy
- Renal failure
- Resistant ovary
- Rud syndrome
- Sertoli-cell-only syndrome
- Suramin
- Surgery
- Swyer's syndrome
- Testicular biosynthetic defects
- Testicular torsion
- Toxins
- Trauma
- Turner syndrome
- Varicocele
- Vascular abnormalities of the cns
- Woodhouse-sakati syndrome
- X-linked mental retardation-hypotonic facies syndrome
- Xx gonadal dysgenesis
- Zinc deficiency
- Hemophilia
- Henoch-schonlein purpura
- Hepatitis a
- Hepatitis b
- Hepatitis c
- Hepatorenal tyrosinemia
- Hereditary hemorrhagic telangiectasia
- Hereditary leiomyomatosis
- Herns syndrome
- Honeymoon bladder
- Hypercalciuria
- Hypertension
- Hypocomplementemic urticarial vasculitis
- Idarubicin
- Iga nephropathy
- Immune thrombocytopenic purpura
- Indandione rodenticide poisoning
- Infective endocarditis
- Interstitial nephritis
- Jaundice
- Juniper tar poisoning
- Kidney cancer
- Kidney stones
- Klerat rodenticide poisoning
- Lactate dehydrogenase deficiency
- Lecithin-cholesterol acyltransferase deficiency
- Leiomyomatosis of esophagus
- Leucinosis
- Leukocytoclastic angiitis
- Liver cancer
- Machupo virus
- Malaria
- Malignant rhabdoid tumors
- Maple syrup urine disease
- Matikus rodenticide poisoning
- Medullary sponge kidney
- Meier-blumberg-imahorn syndrome
- Melanoma
- Membranous nephropathy
- Mepacrine
- Methaemoglobinaemia
- Metronidazole
- Milky urine
- Mitoxantrone
- Monosodium methanarsenate
- Mouser rodenticide poisoninge
- Myoglobinuria
- Nail-patella syndrome
- Naked brimcap poisoning
- Naphthalene
- Nefopam
- Neoplastic porphyria tarda
- Nephritis
- Nephrocalcinosis
- Nephropathy
- Nephrosis
- Nitrates
- Norum disease
- Obstructive jaundice
- Oncocytoma
- Oral contraceptives
- Orchitis
- Oxalosis
- Oxamniquine
- Papillary renal cell carcinoma
- Paragonimiases
- Parkinson's disease
- Pelvic fracture
- Pelvic lipomatosis
- Penis cancer
- Penis conditions
- Penis tourniquet syndrome
- Pennyroyal oil
- Peppermint oil
- Petroleum distillates
- Phenazopyridine
- Phenol
- Phenolphthalein
- Phensuximide
- Phosphine
- Phyllodes tumor of the prostate
- Pierson syndrome
- Pindone rodenticide poisoning
- Pixantrone
- Polycystic kidney disease
- Porphyria
- Precalicial canalicular ectasia
- Prostate cancer
- Prostatic abscess
- Prostatitis
- Pyelonephritis
- Quebec platelet disorder
- Ratak plus rodenticide poisoning
- Reflux nephropathy
- Reiter’s syndrome
- Renal abscess
- Renal cancer
- Renal colic
- Renal failure
- Renal hypertension
- Renal mucormycosis
- Renal nutcracker syndrome
- Renal zygmycosis
- Renovascular hypertension
- Rhabdoid tumor
- Rhabdomyolysis
- Rhubarb
- Rifabutin
- Rifampicin
- Rodend rodenticide poisoning
- Rue
- Salcedo syndrome
- Sarcoma botryoides
- Schistosomiasis
- Senna
- Southworth symptom complex
- Spirochetes disease
- Stones
- Stuart factor deficiency
- Sulphasalazine
- Talon rodenticide poisoning
- Thalassemia
- Thrombasthenia
- Thrombocytopathy
- Thrombocytopenia
- Thrombocytopenic purpura
- Torulopsis
- Toxic epidermal necrolysis
- Toxic mushrooms
- Transitional cell carcinoma
- Trichosporin infection
- Tuberculosis
- Turpentine oil
- Urachal cancer
- Urachal cyst
- Urban schosser spohn syndrome
- Ureter cancer
- Urethral cancer
- Urinary disorders
- Urinary stones
- Urinary system cancer
- Urinary tract infections
- Urod-related porphyria cutanea tarda
- Vasculitis hypersensitivity
- Vasculitis
- Volak rodenticide poisoning
- Volid rodenticide poisoning
- Wegener's granulomatosis
- Weil syndrome
- Wilms tumor
- Wilson's disease
- Xanthic urolithiasis
- Xanthine oxydase deficiency
- Xanthinuria
- Yellow fever