Acromegaly MRI: Difference between revisions
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{{Acromegaly}} | {{Acromegaly}} | ||
{{CMG}} | {{CMG}}; {{AE}} {{AEL}} | ||
==Overview== | ==Overview== | ||
[[Pituitary gland]] MRI may be helpful in the diagnosis of acromegaly as [[Pituitary adenoma|pituitary adenomas]] are the most common cause of acromegaly. Findings on MRI suggestive of acromegaly include enlarged pituitary gland and an [[adenoma]] that may extend to the [[Suprasellar|suprasellar region]]. [[Spine]] MRI also may be helpful in the diagnosis as it shows [[hypertrophy]] of the spinal ligaments. | |||
==MRI== | ==MRI== | ||
*Pituitary MRI may be helpful in the diagnosis of acromegaly. Findings on MRI suggestive of acromegaly include:<ref name="pmid21470998">{{cite journal| author=Famini P, Maya MM, Melmed S| title=Pituitary magnetic resonance imaging for sellar and parasellar masses: ten-year experience in 2598 patients. | journal=J Clin Endocrinol Metab | year= 2011 | volume= 96 | issue= 6 | pages= 1633-41 | pmid=21470998 | doi=10.1210/jc.2011-0168 | pmc=3100749 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21470998 }}</ref> | |||
**[[Pituitary adenoma]] as it is the most common cause of acromegaly and 75% of the patients have [[Macroadenoma of the pituitary gland|macroadenoma]]. On MRI, enlarged pituitary gland with [[gadolinium]] uptake is observed and the [[adenoma]] may extend to the [[Suprasellar|suprasellar region.]] | |||
*[[Spine]] MRI may be helpful also in the diagnosis of acromegaly. Findings on MRI show hypertrophy of spinal ligaments and [[cartilaginous]] structures and features of [[osteoarthritis]]. | |||
*Joints MRI shows [[Ligamentous laxity|ligamentous]] and [[cartilaginous]] hypertrophy and [[crystal]] deposition. | |||
==References== | ==References== | ||
{{ | {{Reflist|2}} | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
Latest revision as of 20:49, 14 August 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]
Overview
Pituitary gland MRI may be helpful in the diagnosis of acromegaly as pituitary adenomas are the most common cause of acromegaly. Findings on MRI suggestive of acromegaly include enlarged pituitary gland and an adenoma that may extend to the suprasellar region. Spine MRI also may be helpful in the diagnosis as it shows hypertrophy of the spinal ligaments.
MRI
- Pituitary MRI may be helpful in the diagnosis of acromegaly. Findings on MRI suggestive of acromegaly include:[1]
- Pituitary adenoma as it is the most common cause of acromegaly and 75% of the patients have macroadenoma. On MRI, enlarged pituitary gland with gadolinium uptake is observed and the adenoma may extend to the suprasellar region.
- Spine MRI may be helpful also in the diagnosis of acromegaly. Findings on MRI show hypertrophy of spinal ligaments and cartilaginous structures and features of osteoarthritis.
- Joints MRI shows ligamentous and cartilaginous hypertrophy and crystal deposition.
References
- ↑ Famini P, Maya MM, Melmed S (2011). "Pituitary magnetic resonance imaging for sellar and parasellar masses: ten-year experience in 2598 patients". J Clin Endocrinol Metab. 96 (6): 1633–41. doi:10.1210/jc.2011-0168. PMC 3100749. PMID 21470998.