Splenic infarction overview: Difference between revisions
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{{Splenic infarction}} | {{Splenic infarction}} | ||
{{CMG}} | {{CMG}} {{AE}} {{asiri}} | ||
==Overview== | ==Overview== | ||
A splenic [[infarct]] occurs when the vascular supply for the [[spleen]] becomes occluded leading to tissue [[hypoxia]] and [[necrosis]]. It can be the result of either [[arterial]] or [[venous]] compromise, and it is associated with multiple of disease states. The most common etiologies include [[malignancy]], [[thrombophilia|hypercoagulable disorders]], and [[embolism|embolic disorders]].<ref> Splenic infarction. Radiopedia.org (2015-2016). http://radiopaedia.org/articles/splenic-infarction Accessed on August 27, 2016</ref><ref name="pmid19328367">{{cite journal| author=Antopolsky M, Hiller N, Salameh S, Goldshtein B, Stalnikowicz R| title=Splenic infarction: 10 years of experience. | journal=Am J Emerg Med | year= 2009 | volume= 27 | issue= 3 | pages= 262-5 | pmid=19328367 | doi=10.1016/j.ajem.2008.02.014 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19328367 }} </ref> It is also common that splenic infarctions are the presenting signs of a previously unknown condition.<ref name="pmid20928991">{{cite journal| author=Lawrence YR, Pokroy R, Berlowitz D, Aharoni D, Hain D, Breuer GS| title=Splenic infarction: an update on William Osler's observations. | journal=Isr Med Assoc J | year= 2010 | volume= 12 | issue= 6 | pages= 362-5 | pmid=20928991 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20928991 }} </ref> Patients can be asymptomatic, however, most develop left upper quadrant [[abdominal pain]]. Splenic infarction is often diagnosed with [[computed tomography]]. Splenic infarcts can be managed medically, however, surgical intervention is indicated if the patient develops complications including [[hemorrhage]], rupture, [[abscess]], or [[pseudocyst]].<ref name="pmid3764696">{{cite journal |author=Jaroch MT, Broughan TA, Hermann RE |title=The natural history of splenic infarction |journal=Surgery |volume=100 |issue=4 |pages=743–50 |year=1986 |month=October |pmid=3764696 |doi= |url=}}</ref> | |||
==Historical Perspective== | |||
==Classification== | |||
==Pathophysiology== | |||
==Causes== | |||
==Differentiating {{PAGENAME}} from Other Diseases== | |||
==Epidemiology and Demographics== | |||
==Risk Factors== | |||
==Screening== | |||
==Natural History, Complications, and Prognosis== | |||
===Natural History=== | |||
===Complications=== | |||
===Prognosis=== | |||
==Diagnosis== | |||
===Diagnostic Criteria=== | |||
===History and Symptoms=== | |||
===Physical Examination=== | |||
===Laboratory Findings=== | |||
===Imaging Findings=== | |||
===Other Diagnostic Studies=== | |||
==Treatment== | |||
===Medical Therapy=== | |||
===Surgery=== | |||
===Prevention=== | |||
==References== | ==References== | ||
Latest revision as of 04:51, 26 September 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Asiri Ediriwickrema, M.D., M.H.S. [2]
Overview
A splenic infarct occurs when the vascular supply for the spleen becomes occluded leading to tissue hypoxia and necrosis. It can be the result of either arterial or venous compromise, and it is associated with multiple of disease states. The most common etiologies include malignancy, hypercoagulable disorders, and embolic disorders.[1][2] It is also common that splenic infarctions are the presenting signs of a previously unknown condition.[3] Patients can be asymptomatic, however, most develop left upper quadrant abdominal pain. Splenic infarction is often diagnosed with computed tomography. Splenic infarcts can be managed medically, however, surgical intervention is indicated if the patient develops complications including hemorrhage, rupture, abscess, or pseudocyst.[4]
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Splenic infarction overview from Other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications, and Prognosis
Natural History
Complications
Prognosis
Diagnosis
Diagnostic Criteria
History and Symptoms
Physical Examination
Laboratory Findings
Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Prevention
References
- ↑ Splenic infarction. Radiopedia.org (2015-2016). http://radiopaedia.org/articles/splenic-infarction Accessed on August 27, 2016
- ↑ Antopolsky M, Hiller N, Salameh S, Goldshtein B, Stalnikowicz R (2009). "Splenic infarction: 10 years of experience". Am J Emerg Med. 27 (3): 262–5. doi:10.1016/j.ajem.2008.02.014. PMID 19328367.
- ↑ Lawrence YR, Pokroy R, Berlowitz D, Aharoni D, Hain D, Breuer GS (2010). "Splenic infarction: an update on William Osler's observations". Isr Med Assoc J. 12 (6): 362–5. PMID 20928991.
- ↑ Jaroch MT, Broughan TA, Hermann RE (1986). "The natural history of splenic infarction". Surgery. 100 (4): 743–50. PMID 3764696. Unknown parameter
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