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| __NOTOC__ | | __NOTOC__ |
| {{Pulmonary aspiration}} | | {{Pulmonary aspiration}} |
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| '''Editor-in-Chief:''' Santosh Patel M.D., FRCA [mailto:santosh.patel@pat.nhs.uk] | | '''Editor-in-Chief:''' Santosh Patel M.D., FRCA [mailto:santosh.patel@pat.nhs.uk] |
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| ==Overview== | | ==[[Pulmonary aspiration overview|Overview]]== |
| In [[medicine]], '''aspiration''' is the entry of secretions or foreign material into the [[Vertebrate trachea|trachea]] and [[lung]]s. The patient may either [[inhalation|inhale]] the material, or it may be blown into the lungs during [[positive pressure ventilation]] or [[CPR]]. As the right main [[bronchus]] is more vertical and of slightly wider lumen than the left, aspirated material is more likely to end up in this branch or one of its subsequent bifurcations.
| | ==[[Pulmonary aspiration pathophysiology |Pathophysiology]]== |
| | | ==[[Pulmonary aspiration causes|Causes]]== |
| ==Risk factors== | | ==[[Pulmonary aspiration differential diagnosis|Differentiating Pulmonary Aspiration from other Diseases]]== |
| As a rule of thumb, any condition which compromises a patient's level of consciousness and/or gag reflex is a risk factor for pulmonary aspiration.
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| Causes of unconsciousness where aspiration may occur include trauma (especially head injuries), poisoning (including drug/alcohol overdose), [[general anaesthetic]]s, and diseases or metabolic conditions. | |
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| [[Gastroesophageal reflux]], a full stomach, [[pregnancy]], and [[obesity]] all increase the risk of aspiration in the semiconscious.
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| Normally [[fasting]] for six hours before elective surgery is enough to empty the stomach. Severe injuries can slow the movement of digesta from the stomach and through the duodenum.
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| Acute [[alcohol poisoning]] is a relatively common cause of severe pulmonary aspiration as the alcohol renders the victim unconscious and can induce [[vomit]]ing. Patients with neurological conditions may also aspirate food or drink.
| | ==[[Pulmonary aspiration epidemiology and demographics|Epidemiology and Demographics]]== |
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| During labour, early respiratory movements by the baby facilitate filling of alveolar ducts and alveolar lumens with elements of [[amniotic fluid]]: amniotic cells, [[squamous]] and squamous cells from fetal skin, [[lanugo]], [[meconium]]. Reduced inflammatory infiltrate ([[neutrophils]]) and capillary congestion is present. Photos at: [http://www.pathologyatlas.ro/Aspiration%20Bronchopneumonia1.html 1]
| | ==[[Pulmonary aspiration risk factors|Risk Factors]]== |
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| ==Causes== | | ==[[Pulmonary aspiration natural history, complications and prognosis|Natural History, Complications and Prognosis]]== |
| | ==Diagnosis== |
| | [[Pulmonary aspiration history and symptoms|History and Symptoms]] | [[Pulmonary aspiration physical examination|Physical Examination]] | [[Pulmonary aspiration laboratory findings|Laboratory Findings]] | [[Pulmonary aspiration chest x ray|Chest X Ray]] | [[Pulmonary aspiration CT|CT]] | [[Pulmonary aspiration MRI|MRI]] | [[Pulmonary aspiration other imaging findings|Other Imaging Findings]] | [[Pulmonary aspiration other diagnostic studies|Other Diagnostic Studies]] |
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| * [[Alcohol]] or [[sedative]] use
| | ==Treatment== |
| * Altered sensorium
| | [[Pulmonary aspiration medical therapy|Medical Therapy]] | [[Pulmonary aspiration surgery|Surgery]] | [[Pulmonary aspiration primary prevention|Primary Prevention]] | [[Pulmonary aspiration cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Pulmonary aspiration future or investigational therapies|Future or Investigational Therapies]] |
| * [[Convulsion]]s
| | ==Case Studies== |
| * Dental, pharyngeal, or airway procedures
| | [[Pulmonary aspiration case study one|Case #1]] |
| * [[General anesthesia]]
| | == Related Chapters == |
| * Impaired [[cough reflex]]
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| * Impaired swallow reflex
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| * [[Loss of consciousness]]
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| * Maxillofacial trauma
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| * [[Mental retardation]]
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| * Poor dentition
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| ==Consequences== | |
| If enough material enters the lungs, the patient may simply drown. However, small volumes of gastric acid contents can fatally damage the delicate lung tissue. Even small volumes of aspirated food may lead to [[bronchopneumonia]] infection. Chronic aspiration may lead to [[bronchiectasis]] and may cause some cases of [[asthma]].
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| ==Prevention==
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| The lungs are normally protected against aspiration by a series of ''protective reflexes'' such as [[coughing]] and [[swallowing]]. Significant aspiration can only occur if the protective reflexes are absent (in neurological disease, [[coma]], [[drug overdose]], [[sedation]] or [[general anesthesia]]). In [[intensive care]], sitting patients up reduces the risk of pulmonary aspiration and ventilator associated pneumonia.
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| Measures to prevent aspiration depend on the situation and the patient. In patients at imminent risk of aspiration, endotracheal [[intubation]] by a trained [[health professional]] provides the best protection. A simpler intervention that can be implemented is to lay the patient on their side in the ''rescue position'' (as taught in [[first aid]] and [[CPR]] classes), so that any vomitus produced by the patient will drain out their mouth instead of back down their pharynx.
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| People with chronic neurological disorders, for example, after a stroke, are less likely to aspirate [[thickened fluids]].
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| The location of abscesses caused by aspiration depends on the position one is in. If one is sitting or standing up, the aspirate ends up in the posterior basal segment of the right lower lobe. If one is on one's back, it goes to the superior segment of the right lower lobe. If one is lying on the right side, it goes to the superior segment of the right middle lobe, or the posterior basal segment of the right upper lobe. If one is lying on the left, it goes to the lingula.
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| == See also == | |
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| * [[Salt water aspiration syndrome]] | | * [[Salt water aspiration syndrome]] |
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| [[Category:Neurology]] | | [[Category:Neurology]] |
| [[Category:Pulmonology]] | | [[Category:Pulmonology]] |
| | [[Category:Emergency medicine]] |
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| [[da:Aspiration (medicinsk)]] | | [[da:Aspiration (medicinsk)]] |