Yersinia pestis infection future or investigational therapies: Difference between revisions
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{{Yersinia pestis infection}} | {{Yersinia pestis infection}} | ||
{{CMG}}; {{AE}} {{JS}} | |||
==Overview== | |||
Current research aims to develop new and less invasive [[vaccines]] that protect from airborne infection of ''[[Yersinia pestis]]''. | |||
==Future and Investigational Therapies== | |||
Research studies are under way to improve the plague [[vaccine]]. The qualities searched in the new [[vaccine]] include:<ref name=Mandell>{{cite book | last = Mandell | first = Gerald | title = Mandell, Douglas, and Bennett's principles and practice of infectious diseases | publisher = Churchill Livingstone/Elsevier | location = Philadelphia, PA | year = 2010 | isbn = 0443068399 }}</ref> | |||
* Protection from airborne [[infection]] | |||
* Inhaled administration | |||
A current potential [[vaccine]] is a recombinant type, expressing both V and F1 [[antigens]] of ''[[Yersinia pestis]]''. This [[vaccine]] appears to protect animals against airborne [[infection]] with ''[[Yersinia pestis]]''. Other options include:<ref name=Mandell>{{cite book | last = Mandell | first = Gerald | title = Mandell, Douglas, and Bennett's principles and practice of infectious diseases | publisher = Churchill Livingstone/Elsevier | location = Philadelphia, PA | year = 2010 | isbn = 0443068399 }}</ref> | |||
* Aerosolized [[monoclonal antibodies]] | |||
* Attenuated form of ''[[Yersinia pseudotuberculosis]]'' | |||
==References== | ==References== | ||
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Latest revision as of 19:31, 18 September 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: João André Alves Silva, M.D. [2]
Overview
Current research aims to develop new and less invasive vaccines that protect from airborne infection of Yersinia pestis.
Future and Investigational Therapies
Research studies are under way to improve the plague vaccine. The qualities searched in the new vaccine include:[1]
- Protection from airborne infection
- Inhaled administration
A current potential vaccine is a recombinant type, expressing both V and F1 antigens of Yersinia pestis. This vaccine appears to protect animals against airborne infection with Yersinia pestis. Other options include:[1]
- Aerosolized monoclonal antibodies
- Attenuated form of Yersinia pseudotuberculosis
References
- ↑ 1.0 1.1 Mandell, Gerald (2010). Mandell, Douglas, and Bennett's principles and practice of infectious diseases. Philadelphia, PA: Churchill Livingstone/Elsevier. ISBN 0443068399.