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==Overview==
'''Renal agenesis''' is the absence of one (unilateral) or both (bilateral) [[kidney]]s at birth. '''Renal agenesis''' is a medical condition in which one (unilateral) or both (bilateral) fetal [[kidney]]s fail to develop.


It can be associated with ''[[RET proto-oncogene|RET]]'' or ''[[UPK3A]]''.<ref>{{OMIM|191830}}</ref>
{{Renal agenesis}}


==Bilateral renal [[agenesis]]==
'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''
Bilateral renal agenesis is uncommon and is a serious condition. See [[Potter syndrome]].


Bilateral Renal Agenesis is the absence of both kidneys at birth. It is a genetic disorder characterized by a failure of the kidneys to develop in a fetus. This absence of kidneys causes a deficiency of amniotic fluid (Oligohydramnios) in a pregnant woman. Normally, the amniotic fluid acts as a cushion for the developing fetus. When there is an insufficient amount of this fluid, compression of the fetus may occur resulting in further malformations of the baby.
{{CMG}} {{AE}} {{SHA}}


This disorder is more common in infants born of a parent who has a kidney malformation, particularly the absence of one kidney (unilateral renal agenesis). Studies have proven that unilateral renal agenesis and bilateral renal agenesis are genetically related. 1 in 3 infants with this congenital defect are still born. Most infants that are born alive do not live beyond four hours.
{{SK}}: Solitary kidney, unilateral renal agenesis, bilateral renal agenesis


==Unilateral renal [[agenesis]]==
==[[Renal agenesis overview|Overview]]==
This is much more common, but is not usually of any major concern, as long as the other kidney is healthy. The odds of a person being born with this condition are roughly 1 in 5000. Adults with unilateral renal agenesis have considerably higher chances of hypertension and high blood pressure. Most contact sports would be advised against.
 
==External links==
==[[Renal agenesis classification|Classification]]==
* {{Chorus|00464}}
 
<br>
==[[Renal agenesis pathophysiology|Pathophysiology]]==
==References==
 
{{reflist|2}}
==[[Renal agenesis causes|Causes]]==
 
==[[Renal agenesis epidemiology and demographics|Epidemiology and Demographics]]==
 
==[[Renal agenesis screening|Screening]]==
 
==[[Renal agenesis natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
 
==Diagnosis==
 
[[Renal agenesis history and symptoms|History and Symptoms]] | [[Renal agenesis physical examination|Physical Examination]] | [[Renal agenesis CT|CT]] | [[Renal agenesis MRI|MRI]] | [[Renal agenesis ultrasound|Ultrasound]] | [[Renal agenesis other imaging findings|Other Imaging Findings]] | [[Renal agenesis other diagnostic studies|Other Diagnostic Studies]]
 
==Treatment==
 
[[Renal agenesis medical therapy|Medical Therapy]] | [[Renal agenesis surgery|Surgery]] | [[Renal agenesis primary prevention|Primary Prevention]] | [[Renal agenesis secondary prevention|Secondary Prevention]] | [[Renal agenesis cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Renal agenesis future or investigational therapies|Future or Investigational Therapies]]
 
==Case Studies==
[[Renal agenesis case study one|Case #1]]


{{Congenital malformations of genital organs and urinary system}}
{{Congenital malformations of genital organs and urinary system}}


[[Category:Disease]]
[[Category:Kidney diseases]]
[[Category:Kidney diseases]]
[[Category:Needs content]]


[[es:Agenesia renal]]
[[es:Agenesia renal]]

Latest revision as of 11:26, 1 August 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shakiba Hassanzadeh, MD[2]

Synonyms and keywords:: Solitary kidney, unilateral renal agenesis, bilateral renal agenesis

Overview

Classification

Pathophysiology

Causes

Epidemiology and Demographics

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | CT | MRI | Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

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Case #1

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