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{{ACM}} {{SemRikken}}


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| colspan="1" style="text-align:center; background:LightGreen"|[[ACC AHA guidelines classification scheme#Classification of Recommendations|Class I]]
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|bgcolor="LightGreen" | '''a.'''  LDL-C should be <100 mg/dL.  ([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: A]])
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|bgcolor="LightGreen" |'''b.'''  If baseline LDL-C is ≥100 mg/dL, initiate LDL-lowering drug therapy.  ([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: A]])
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|bgcolor="LightGreen" |'''c.''' If on-treatment LDL-C is ≥100 mg/dL, intensify LDL-lowering drug therapy (may require LDL-lowering drug combination).  ([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: A]])
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|bgcolor="LightGreen" |'''d.'''  If triglycerides are 200 to 499 mg/dL, non-HDL-C should be <130 mg/dL.  ([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence:B]])
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|bgcolor="LightGreen" |'''e.''' Therapeutic options to reduce non HDL - C are more intense LDL - C lowering therapy. ([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence:B]])
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|bgcolor="LightGreen" |


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|colspan="1" style="text-align:center; background:LightCoral"| [[ACC AHA guidelines classification scheme#Classification of Recommendations|Class III]] (No Benefit)
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|bgcolor="LightCoral"|'''1.''' Genetic testing is not indicated in relatives when the index patient does not have a definitive pathogenic mutation. ([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: B]])
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|bgcolor="LightCoral"|'''2.''' Ongoing clinical screening is not indicated in genotype-negative relatives in families with [[HOCM]]. ([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: B]])
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| colspan="1" style="text-align:center; background:LemonChiffon"|[[ACC AHA guidelines classification scheme#Classification of Recommendations|Class IIa]]
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|bgcolor="LemonChiffon"|'''a.''' Reduction of LDL-C to <70 mg/dL is reasonable. ([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence:A]])
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|bgcolor="LemonChiffon"|'''b.''' If baseline LDL-C is 70 to 100 mg/dL, it is reasonable to treat to LDL-C <70 mg/dL. ([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence:B]])
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|bgcolor="LemonChiffon"|'''c.''' If triglycerides are 200 to 499 mg/dL, reduction of non-HDL-C to <100 mg/dL is reasonable. ([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence:B]])
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|bgcolor="LemonChiffon"|'''d.''' Therapeutic options to reduce non HDL - C are [[Niacin]] (after LDL-C loweing therapy).  ([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence:B]])
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|bgcolor="LemonChiffon"|'''e.''' Therapeutic options to reduce non HDL - C are [[Fibrate]] therapy (after LDL-C loweing therapy). ([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence:B]])
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Latest revision as of 21:12, 21 October 2024