Schistosomiasis natural history, complications and prognosis: Difference between revisions

Jump to navigation Jump to search
← Older edit
VisualWikitext
Hardik Patel (talk | contribs)
nocaptcha
5,256 edits
No edit summary
Aditya Ganti (talk | contribs)
Bureaucrats, bureaucrats, nocaptcha, Administrators
11,402 edits
 
(18 intermediate revisions by 7 users not shown)
Line 1: Line 1:
__NOTOC__
__NOTOC__
{{Schistosomiasis}}
{{Schistosomiasis}}
{{CMG}}
{{CMG}} ; {{AE}} {{ADG}}
==Overview==
If left untreated, most of the patients with schistosomiasis may progress to develop ulceration or [[cancer of the bladder]], [[liver]] or [[kidney failure]]. Common complications of schistosomiasis include [[hematuria]], [[malnutrition]], [[Polyps|intestinal polyps]], [[hydronephrosis]], [[glomerulonephritis]], bladder [[Polyp|polyps]], [[Bladder cancer|bladder cancer,]] [[infertility]], [[ectopic pregnancy]], [[renal failure]], and [[Cor pulmonale|cor-pulmonale]]. Depending on the extent of the disease progression at the time of diagnosis, the prognosis of schistosomiasis may vary. However, the prognosis is generally regarded as good with treatment.
==Natural History==
If left untreated, most of the patients with [[schistosomiasis]] may progress to develop [[ulceration]] or [[cancer of the bladder]], [[liver]] or [[kidney failure]].<ref name="pmid25183124">{{cite journal |vauthors=Gundamaraju R |title=Novel antipathy for schistosomiasis-the most lethal ailment of the tropical region |journal=Asian Pac J Trop Biomed |volume=4 |issue=Suppl 1 |pages=S43–5 |year=2014 |pmid=25183124 |pmc=4025338 |doi=10.12980/APJTB.4.2014C831 |url=}}</ref>


Please help WikiDoc by adding more content here. It's easy!  Click  [[Help:How_to_Edit_a_Page|here]] to learn about editing.
==Complications==
Common complications of schistosomiasis include:<ref name="pmid11469998">{{cite journal |vauthors=Schafer TW, Hale BR |title=Gastrointestinal complications of schistosomiasis |journal=Curr Gastroenterol Rep |volume=3 |issue=4 |pages=293–303 |year=2001 |pmid=11469998 |doi= |url=}}</ref><ref name="pmid11819515">{{cite journal |vauthors=Wu GY, Halim MH |title=Schistosomiasis: progress and problems |journal=World J. Gastroenterol. |volume=6 |issue=1 |pages=12–19 |year=2000 |pmid=11819515 |pmc=4723577 |doi= |url=}}</ref>
*[[Hematuria]]
*[[Malnutrition]]
*[[Growth retardation]]
*[[Anemia of chronic disease]]
*[[Cervicitis]]
*[[Iron deficiency anemia|Iron-deficiency anemia]]
*[[Splenomegaly]]
*[[Polyps|Intestinal polyps]]
*[[Hydronephrosis]]
*[[Glomerulonephritis]]
*[[Salmonella infections|Recurrent Salmonella bacteremia]]
*Bladder polyps
*[[Bladder cancer]]
*[[Infertility]]
*[[Ectopic pregnancy]]
*[[Portal hypertension]]
*[[Esophageal varices]]
*[[Ascites]]
*[[Intestinal obstruction]]
*[[Obstructive uropathy]]
*[[Renal failure]]
*[[Seizures|Generalized seizures]]
*[[Spinal cord compression]]
*[[Cor pulmonale]]


==Overview==
==Prognosis==
==Complications==
*Depending on the extent of the [[disease]] progression at the time of diagnosis, the [[prognosis]] of schistosomiasis may vary.
Above all, schistosomiasis is a [[chronic disease]].  Pathology of ''S. mansoni'' and  ''S. japonicum'' schistosomiasis includes: [[Katayama fever]], hepatic perisinusoidal egg [[granulomas]], Symmers’ pipe stem periportal fibrosis, [[portal hypertension]], and occasional [[embolism|embolic]] egg granulomas in [[brain]] or [[spinal cord]]. Pathology of ''S. haematobium'' schistosomiasis includes: [[hematuria]], [[scar]]ring, [[calcification]], [[squamous cell carcinoma]], and occasional embolic egg granulomas in brain or spinal cord.  [[Bladder cancer]] diagnosis and mortality are generally elevated in affected areas.
*Prognosis is good with treatment.
*The 1-year [[mortality]] rate of patients with schistosomiasis ranges approximately 0.1-11% depending upon underlying [[complications]].
*If symptoms of schistosomiasis persists after 2 rounds of [[praziquantel]] treatment, more [[urine]] or [[stool]] samples should be taken and tested for viable [[Parasites|parasite]] eggs, and re-treatment must be given if persistent [[infection]] is detected.<ref name="urlCDC - Schistosomiasis - Resources for Health Professionals">{{cite web |url=https://www.cdc.gov/parasites/schistosomiasis/health_professionals/index.html |title=CDC - Schistosomiasis - Resources for Health Professionals |format= |work= |accessdate=}}</ref><ref name="urlWHO | Schistosomiasis">{{cite web |url=http://www.who.int/mediacentre/factsheets/fs115/en/ |title=WHO &#124; Schistosomiasis |format= |work= |accessdate=}}</ref>


==References==
==References==
{{Reflist|2}}


{{Reflist|2}}
[[Category:Disease]]
[[Category:Needs content]]
[[Category:Water-borne diseases]]
[[Category:Water-borne diseases]]
[[Category:Parasitic diseases]]
[[Category:Parasitic diseases]]
Line 19: Line 50:
[[Category:Hepatology]]
[[Category:Hepatology]]
[[Category:Neglected diseases]]
[[Category:Neglected diseases]]
[[Category:Infectious disease]]

Latest revision as of 18:11, 5 July 2020

Schistosomiasis Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Schistosomiasis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

Echocardiography and Ultrasound

CT scan

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Schistosomiasis natural history, complications and prognosis On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Schistosomiasis natural history, complications and prognosis

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Schistosomiasis natural history, complications and prognosis

CDC on Schistosomiasis natural history, complications and prognosis

Schistosomiasis natural history, complications and prognosis in the news

Blogs on Schistosomiasis natural history, complications and prognosis

Directions to Hospitals Treating Schistosomiasis

Risk calculators and risk factors for Schistosomiasis natural history, complications and prognosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]

Overview

If left untreated, most of the patients with schistosomiasis may progress to develop ulceration or cancer of the bladder, liver or kidney failure. Common complications of schistosomiasis include hematuria, malnutrition, intestinal polyps, hydronephrosis, glomerulonephritis, bladder polyps, bladder cancer, infertility, ectopic pregnancy, renal failure, and cor-pulmonale. Depending on the extent of the disease progression at the time of diagnosis, the prognosis of schistosomiasis may vary. However, the prognosis is generally regarded as good with treatment.

Natural History

If left untreated, most of the patients with schistosomiasis may progress to develop ulceration or cancer of the bladder, liver or kidney failure.[1]

Complications

Common complications of schistosomiasis include:[2][3]

Prognosis

  • Depending on the extent of the disease progression at the time of diagnosis, the prognosis of schistosomiasis may vary.
  • Prognosis is good with treatment.
  • The 1-year mortality rate of patients with schistosomiasis ranges approximately 0.1-11% depending upon underlying complications.
  • If symptoms of schistosomiasis persists after 2 rounds of praziquantel treatment, more urine or stool samples should be taken and tested for viable parasite eggs, and re-treatment must be given if persistent infection is detected.[4][5]

References

  1. ↑ Gundamaraju R (2014). "Novel antipathy for schistosomiasis-the most lethal ailment of the tropical region". Asian Pac J Trop Biomed. 4 (Suppl 1): S43–5. doi:10.12980/APJTB.4.2014C831. PMC 4025338. PMID 25183124.
  2. ↑ Schafer TW, Hale BR (2001). "Gastrointestinal complications of schistosomiasis". Curr Gastroenterol Rep. 3 (4): 293–303. PMID 11469998.
  3. ↑ Wu GY, Halim MH (2000). "Schistosomiasis: progress and problems". World J. Gastroenterol. 6 (1): 12–19. PMC 4723577. PMID 11819515.
  4. ↑ "CDC - Schistosomiasis - Resources for Health Professionals".
  5. ↑ "WHO | Schistosomiasis".
Retrieved from "https://www.wikidoc.org/index.php?title=Schistosomiasis_natural_history,_complications_and_prognosis&oldid=1621523"