Renal agenesis epidemiology and demographics: Difference between revisions
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{{Renal agenesis}} | {{Renal agenesis}} | ||
{{CMG}} {{AE}} {{SHA}} | |||
== Overview == | |||
The general [[incidence]] of unilateral renal agenesis (URA) has been reported to be approximately 1 in 2031 individuals. [[Male|Males]] are more commonly affected by unilateral renal agenesis (URA) than [[Female|females]]. The [[incidence]] of bilateral renal agenesis (BRA) is approximately 1 in every 3000 pregnancies. The [[mortality rate]] of bilateral renal agenesis (BRA) without [[Prenatal development|prenatal]] therapy is 100 %. | |||
== Epidemiology and Demographics == | |||
=== Incidence === | |||
* The general [[incidence]] of unilateral renal agenesis (URA) has been reported to be approximately 1 in 2031 individuals, however, the [[incidence]] of URA based on prenatal studies alone has been reported to be 1 in 8091.<ref name="pmid23449343">{{cite journal| author=Westland R, Schreuder MF, Ket JC, van Wijk JA| title=Unilateral renal agenesis: a systematic review on associated anomalies and renal injury. | journal=Nephrol Dial Transplant | year= 2013 | volume= 28 | issue= 7 | pages= 1844-55 | pmid=23449343 | doi=10.1093/ndt/gft012 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23449343 }} </ref> | |||
* The [[incidence]] of bilateral renal agenesis (BRA) is approximately 1 in every 3000 pregnancies.<ref name="pmid25004316">{{cite journal| author=Bienstock JL, Birsner ML, Coleman F, Hueppchen NA| title=Successful in utero intervention for bilateral renal agenesis. | journal=Obstet Gynecol | year= 2014 | volume= 124 | issue= 2 Pt 2 Suppl 1 | pages= 413-5 | pmid=25004316 | doi=10.1097/AOG.0000000000000339 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25004316 }} </ref><ref name="pmid10846770">{{cite journal| author=Isaksen CV, Eik-Nes SH, Blaas HG, Torp SH| title=Fetuses and infants with congenital urinary system anomalies: correlation between prenatal ultrasound and postmortem findings. | journal=Ultrasound Obstet Gynecol | year= 2000 | volume= 15 | issue= 3 | pages= 177-85 | pmid=10846770 | doi=10.1046/j.1469-0705.2000.00065.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10846770 }} </ref> | |||
=== Prevalence === | |||
A report showed that the overall [[prevalence]] of unilateral renal agenesis (URA) was 4 per 10,000 in all births which included terminations of [[pregnancy]] (TOP) and [[Intrauterine death|intrauterine deaths (IUD)]].<ref name="pmid28722320">{{cite journal| author=Laurichesse Delmas H, Kohler M, Doray B, Lémery D, Francannet C, Quistrebert J | display-authors=etal| title=Congenital unilateral renal agenesis: Prevalence, prenatal diagnosis, associated anomalies. Data from two birth-defect registries. | journal=Birth Defects Res | year= 2017 | volume= 109 | issue= 15 | pages= 1204-1211 | pmid=28722320 | doi=10.1002/bdr2.1065 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28722320 }} </ref> | |||
=== Mortality rate === | |||
The [[mortality rate]] of bilateral renal agenesis (BRA) without [[Prenatal development|prenatal]] therapy is 100%.<ref name="pmid31098643">{{cite journal| author=Huber C, Shazly SA, Blumenfeld YJ, Jelin E, Ruano R| title=Update on the Prenatal Diagnosis and Outcomes of Fetal Bilateral Renal Agenesis. | journal=Obstet Gynecol Surv | year= 2019 | volume= 74 | issue= 5 | pages= 298-302 | pmid=31098643 | doi=10.1097/OGX.0000000000000670 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31098643 }} </ref> | |||
=== Gender === | |||
[[Male|Males]] are more commonly affected by unilateral renal agenesis (URA) than [[Female|females]]. It has been reported that 63% of the patients with URA are [[male]].<ref name="pmid23449343">{{cite journal| author=Westland R, Schreuder MF, Ket JC, van Wijk JA| title=Unilateral renal agenesis: a systematic review on associated anomalies and renal injury. | journal=Nephrol Dial Transplant | year= 2013 | volume= 28 | issue= 7 | pages= 1844-55 | pmid=23449343 | doi=10.1093/ndt/gft012 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23449343 }} </ref> | |||
==References== | ==References== | ||
Latest revision as of 13:23, 2 August 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shakiba Hassanzadeh, MD[2]
Overview
The general incidence of unilateral renal agenesis (URA) has been reported to be approximately 1 in 2031 individuals. Males are more commonly affected by unilateral renal agenesis (URA) than females. The incidence of bilateral renal agenesis (BRA) is approximately 1 in every 3000 pregnancies. The mortality rate of bilateral renal agenesis (BRA) without prenatal therapy is 100 %.
Epidemiology and Demographics
Incidence
- The general incidence of unilateral renal agenesis (URA) has been reported to be approximately 1 in 2031 individuals, however, the incidence of URA based on prenatal studies alone has been reported to be 1 in 8091.[1]
- The incidence of bilateral renal agenesis (BRA) is approximately 1 in every 3000 pregnancies.[2][3]
Prevalence
A report showed that the overall prevalence of unilateral renal agenesis (URA) was 4 per 10,000 in all births which included terminations of pregnancy (TOP) and intrauterine deaths (IUD).[4]
Mortality rate
The mortality rate of bilateral renal agenesis (BRA) without prenatal therapy is 100%.[5]
Gender
Males are more commonly affected by unilateral renal agenesis (URA) than females. It has been reported that 63% of the patients with URA are male.[1]
References
- ↑ 1.0 1.1 Westland R, Schreuder MF, Ket JC, van Wijk JA (2013). "Unilateral renal agenesis: a systematic review on associated anomalies and renal injury". Nephrol Dial Transplant. 28 (7): 1844–55. doi:10.1093/ndt/gft012. PMID 23449343.
- ↑ Bienstock JL, Birsner ML, Coleman F, Hueppchen NA (2014). "Successful in utero intervention for bilateral renal agenesis". Obstet Gynecol. 124 (2 Pt 2 Suppl 1): 413–5. doi:10.1097/AOG.0000000000000339. PMID 25004316.
- ↑ Isaksen CV, Eik-Nes SH, Blaas HG, Torp SH (2000). "Fetuses and infants with congenital urinary system anomalies: correlation between prenatal ultrasound and postmortem findings". Ultrasound Obstet Gynecol. 15 (3): 177–85. doi:10.1046/j.1469-0705.2000.00065.x. PMID 10846770.
- ↑ Laurichesse Delmas H, Kohler M, Doray B, Lémery D, Francannet C, Quistrebert J; et al. (2017). "Congenital unilateral renal agenesis: Prevalence, prenatal diagnosis, associated anomalies. Data from two birth-defect registries". Birth Defects Res. 109 (15): 1204–1211. doi:10.1002/bdr2.1065. PMID 28722320.
- ↑ Huber C, Shazly SA, Blumenfeld YJ, Jelin E, Ruano R (2019). "Update on the Prenatal Diagnosis and Outcomes of Fetal Bilateral Renal Agenesis". Obstet Gynecol Surv. 74 (5): 298–302. doi:10.1097/OGX.0000000000000670. PMID 31098643.