Caroli's disease pathophysiology: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Caroli's disease}} | {{Caroli's disease}} | ||
{{CMG}} | {{CMG}} | ||
== Pathophysiology== | == Pathophysiology== | ||
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* Type I (75-85%) | * Type I (75-85%) | ||
:* Choledochal cysts - cystic dilatation of the common bile duct (CBD) | :* Choledochal cysts - cystic dilatation of the common bile duct (CBD) | ||
:* Often presents during infancy with significant liver disease. | |||
* Type II (2-3%) | * Type II (2-3%) | ||
:* Diverticulae anywhere in the extrahepatic ducts. | :* Diverticulae anywhere in the extrahepatic ducts. | ||
:* Presenting symptoms’s may reflect cystic compression of nearby structures. | |||
* Type III (1-5%) | * Type III (1-5%) | ||
:* Choledochocele cysts | :* Choledochocele cysts | ||
:* Often present with pain and obstructive jaundice; many have pancreatitis. | |||
* Type IV (18-20%) | * Type IV (18-20%) | ||
:* IVA – Multiple cysts in the Intra- and Extra-hepatic ducts | :* IVA – Multiple cysts in the Intra- and Extra-hepatic ducts | ||
| Line 27: | Line 24: | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Gastroenterology]] | [[Category:Gastroenterology]] | ||
[[Category:Needs overview]] | |||
Latest revision as of 16:02, 19 November 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Pathophysiology
- Biliary cysts have been described throughout the biliary system, and are classified according to their location and anatomy.
- Many biliary cysts are congenitally acquired, perhaps as a consequence of unequal proliferation of epithelial cells during embryonic biliary duct development. Some biliary cysts are acquired, and some may develop in association with anatomic variations that lead to abnormally high ductal pressures in association with other predisposing factors.
- Type I (75-85%)
- Choledochal cysts - cystic dilatation of the common bile duct (CBD)
- Often presents during infancy with significant liver disease.
- Type II (2-3%)
- Diverticulae anywhere in the extrahepatic ducts.
- Presenting symptoms’s may reflect cystic compression of nearby structures.
- Type III (1-5%)
- Choledochocele cysts
- Often present with pain and obstructive jaundice; many have pancreatitis.
- Type IV (18-20%)
- IVA – Multiple cysts in the Intra- and Extra-hepatic ducts
- IVB – Multiple cysts in the Extra-hepatic ducts only
- Type V – Caroli’s Disease - rare
- Single or Multiple Intrahepatic bile duct cysts