Echinococcosis history and symptoms: Difference between revisions

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{{Echinococcosis}}
{{Echinococcosis}}


{{CMG}} '''Associate Editor-In-Chief:''' {{CZ}}; {{KD}}
{{CMG}} '''Associate Editor-In-Chief:''' {{MIR}} ; {{CZ}}; {{KD}}
==Overview==
Persons with [[echinococcosis]] often remain [[asymptomatic]]. The clinical presentation of [[echinococcosis]] [[infection]] depends upon the site of the [[cysts]] and their size. The [[cysts]] are mainly found in the [[liver]] and [[lungs]] but can also appear in the [[brain]], [[eyes]], [[spleen]], [[Kidney|kidneys]], [[heart]], [[bone]], and [[central nervous system]]. [[Cyst]] rupture is most frequently caused by [[Physical trauma|trauma]] and may cause mild to severe [[Anaphylactic reaction|anaphylactic reactions]], even death, as a result of the release of [[cystic]] [[fluid]].<ref name="pmid3362862">{{cite journal |vauthors=Chakraborty R, Smouse PE |title=Recombination of haplotypes leads to biased estimates of admixture proportions in human populations |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=85 |issue=9 |pages=3071–4 |year=1988 |pmid=3362862 |pmc=280145 |doi= |url=}}</ref>
 
==History and Symptoms==
==History and Symptoms==
Persons with [[echinococcosis]] often remain [[asymptomatic]]. The clinical presentation of [[echinococcosis]] [[infection]] depends upon the site of the [[Cyst|cysts]] and their size. The [[cysts]] are mainly found in the [[liver]] and [[lungs]] but can also appear in the [[brain]], [[eyes]], [[spleen]], [[Kidney|kidneys]], [[heart]], [[bone]], and [[central nervous system]]. [[Cyst]] rupture is most frequently caused by [[trauma]] and may cause mild to severe [[Anaphylactic reaction|anaphylactic reactions]], even death, as a result of the release of [[cystic]] [[fluid]].


Persons with Cystic echinococcosis often remain asymptomatic until hydatid cysts containing the parasites grow large enough to cause discomfort, pain, nausea, and vomiting. The cysts grow over the course of several years before reaching maturity and the rate at which symptoms appear typically depend on the location of the cyst. The cysts are mainly found in the liver and lungs but can also appear in the [[brain]], [[eyes]], [[spleen]], [[kidney]]s, [[heart]], [[bone]], and [[central nervous system]]. A liver cyst may produce no symptoms for 10 - 20 years until it is large enough to be felt by physical examination.In the lungs, ruptured cyst membranes may be coughed up through the bronchi, resulting in a cure. Cyst rupture is most frequently caused by trauma and may cause mild to severe [[anaphylactic reaction]]s, even [[death]], as a result of the release of cystic fluid.
=== Common symptoms ===
Hepatic:
* No [[symptoms]] (if cysts are less than <10cms)
* [[Hepatomegaly]]
* [[Right upper quadrant pain]]
* [[Nausea and vomiting]]
* [[Cysts]] can rupture into the [[biliary tree]] and produce [[biliary colic]], [[obstructive jaundice]], [[cholangitis]], or [[pancreatitis]]
* Mass effects on the [[bile ducts]], [[portal]] and [[hepatic veins]], or on the [[inferior vena cava]] can result in [[cholestasis]], [[portal hypertension]], [[venous]] [[obstruction]], or the [[Budd-Chiari syndrome]]
Pulmonary:
* [[Cough]]  
* [[Chest pain]]  
* [[Dyspnea]] 
* [[Hemoptysis]]  


Alveolar echinococcosis is characterized by parasitic cysts in the [[liver]] and other organs including the [[lungs]] and brain. AE in humans is similar to that in the natural hosts but differs in that the larval cyst is inhibited from completing development by the host. The cysts invade and destroy surrounding tissues and cause discomfort or [[pain]], [[weight loss]], and [[malaise]]. AE is a dangerous disease resulting in a mortality rate between 50% and 75% and is made worse because of the remote locations and poor health care where cases are found.
=== Less common symptoms ===
 
Pulmonary:
Symptoms include:
* [[Malaise]]
* Pain in the upper right part of the abdomen
* [[Nausea and vomiting]]
* Bloody [[sputum]]
* [[Thoracic]] deformations
* [[Chest pain]]
CNS:
* [[Cough]]
* [[Seizure|Seizures]]  
* [[Fever]]
Cardiac:
* Severe skin [[itching]]
* [[Dyspnea]]  
*[[Nausea]]
* Chest pain
* [[Vomiting]]
Renal:
* [[Hematuria]]
* [[flank pain]]


* [[Pitting edema]]
== References ==
== References ==
{{reflist|2}}
{{reflist|2}}
{{WH}}
{{WS}}


[[Category:Parasitic diseases]]
[[Category:Parasitic diseases]]
[[Category:Infectious disease]]
[[Category:Disease]]
[[Category:Disease]]
[[Category:Needs overview]]
[[Category:Needs overview]]
 
[[Category:Emergency medicine]]
{{WH}}
[[Category:Up-To-Date]]
{{WS}}
[[Category:Infectious disease]]
[[Category:Hepatology]]
[[Category:Gastroenterology]]
[[Category:Surgery]]

Latest revision as of 21:32, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor-In-Chief: Mahshid Mir, M.D. [2] ; Cafer Zorkun, M.D., Ph.D. [3]; Kalsang Dolma, M.B.B.S.[4]

Overview

Persons with echinococcosis often remain asymptomatic. The clinical presentation of echinococcosis infection depends upon the site of the cysts and their size. The cysts are mainly found in the liver and lungs but can also appear in the brain, eyes, spleen, kidneys, heart, bone, and central nervous system. Cyst rupture is most frequently caused by trauma and may cause mild to severe anaphylactic reactions, even death, as a result of the release of cystic fluid.[1]

History and Symptoms

Persons with echinococcosis often remain asymptomatic. The clinical presentation of echinococcosis infection depends upon the site of the cysts and their size. The cysts are mainly found in the liver and lungs but can also appear in the brain, eyes, spleen, kidneys, heart, bone, and central nervous system. Cyst rupture is most frequently caused by trauma and may cause mild to severe anaphylactic reactions, even death, as a result of the release of cystic fluid.

Common symptoms

Hepatic:

Pulmonary:

Less common symptoms

Pulmonary:

CNS:

Cardiac:

Renal:

References

  1. Chakraborty R, Smouse PE (1988). "Recombination of haplotypes leads to biased estimates of admixture proportions in human populations". Proc. Natl. Acad. Sci. U.S.A. 85 (9): 3071–4. PMC 280145. PMID 3362862.

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