Hantavirus infection history and symptoms: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Hantavirus | {{Hantavirus infection}} | ||
{{CMG}} {{AE}} {{MMF}} | |||
==Overview== | |||
The symptoms of hantavirus infection may include sudden [[fever]], [[prostration]], [[myalgia]], and [[abdominal discomfort]]. [[Pulmonary]] and [[hemorrhagic]] symptoms may also arise in severe disease. | |||
{{ | ==History and symptoms== | ||
===History=== | |||
Patient usually presents with history of flu-like illness. History of rodent or rodent dropping contact may be helpful.<ref name="pmid8004332">{{cite journal |vauthors=Levy H, Simpson SQ |title=Hantavirus pulmonary syndrome |journal=Am. J. Respir. Crit. Care Med. |volume=149 |issue=6 |pages=1710–3 |year=1994 |pmid=8004332 |doi=10.1164/ajrccm.149.6.8004332 |url=}}</ref> | |||
===Common symptoms=== | |||
The common symptoms of hantavirus infection are:<ref name="pmid28120221">{{cite journal |vauthors=Jiang H, Zheng X, Wang L, Du H, Wang P, Bai X |title=Hantavirus infection: a global zoonotic challenge |journal=Virol Sin |volume=32 |issue=1 |pages=32–43 |year=2017 |pmid=28120221 |doi=10.1007/s12250-016-3899-x |url=}}</ref> | |||
*Sudden [[fever]] | |||
*[[Prostration]] | |||
*[[Myalgia]] | |||
*[[Abdominal discomfort]] | |||
== | ===Less common symptoms=== | ||
In severe disease (cardiopulmonary or hemorrhagic fever), hantavirus infection can cause the following symptoms:The common symptoms of hantavirus infection are:<ref name="pmid28120221">{{cite journal |vauthors=Jiang H, Zheng X, Wang L, Du H, Wang P, Bai X |title=Hantavirus infection: a global zoonotic challenge |journal=Virol Sin |volume=32 |issue=1 |pages=32–43 |year=2017 |pmid=28120221 |doi=10.1007/s12250-016-3899-x |url=}}</ref> | |||
*Dry [[cough]] | |||
*Rapidly increasing [[dyspnea]] | |||
*[[Petechiae]] | |||
*Inflammatory symptoms of the eye | |||
*Acute [[myopia]] | |||
*[[Altered mental status]] | |||
*[[Hypotension]] | |||
===Symptomatic stages of Hantavirus hemorrhagic fever with renal syndrome=== | |||
On the basis of symptoms, hemorrhagic fever with renal syndrome caused by hantavirus infection is divided into the following stages:<ref name="pmid28120221">{{cite journal |vauthors=Jiang H, Zheng X, Wang L, Du H, Wang P, Bai X |title=Hantavirus infection: a global zoonotic challenge |journal=Virol Sin |volume=32 |issue=1 |pages=32–43 |year=2017 |pmid=28120221 |doi=10.1007/s12250-016-3899-x |url=}}</ref><ref name="pmid12521363">{{cite journal |vauthors=Lednicky JA |title=Hantaviruses. a short review |journal=Arch. Pathol. Lab. Med. |volume=127 |issue=1 |pages=30–5 |year=2003 |pmid=12521363 |doi=10.1043/0003-9985(2003)127<30:>2.0.CO;2 |url=}}</ref><ref name="pmid22553984">{{cite journal |vauthors=Sargianou M, Watson DC, Chra P, Papa A, Starakis I, Gogos C, Panos G |title=Hantavirus infections for the clinician: from case presentation to diagnosis and treatment |journal=Crit. Rev. Microbiol. |volume=38 |issue=4 |pages=317–29 |year=2012 |pmid=22553984 |doi=10.3109/1040841X.2012.673553 |url=}}</ref> | |||
#Prodormal or Febrile phase(3-5 days):It may include | |||
#*[[Fever]] | |||
#*[[Headache]] | |||
#*[[Malaise]] | |||
#*[[Myalgia]] | |||
#*[[Abdominal discomfort]] | |||
#Hemorrhagic phase(1-2 days): It may include | |||
#*[[Flushing]] of the face | |||
#*[[Conjunctival injection|Injection of the conjunctiva]] | |||
#*[[Bleeding]] from mucous membranes | |||
#*[[Petechial rash]] | |||
#*[[Nausea and vomiting]] | |||
#*[[Hypotension]] | |||
#*[[Confusion]] | |||
#*[[Cold]] skin | |||
#Oliguric phase (3-5 days): | |||
#*Decreased urine output which may result in [[renal failure]] | |||
#*Resolution of petechiae and flushing | |||
#Polyuric phase: | |||
#*Onset of [[diuresis]] | |||
#*Clinical improvement | |||
#Convalescent phase (weeks to months): | |||
#*[[Muscle weakness]] | |||
#*Hyposthenuria | |||
#*[[Polyuria]] | |||
===Symptomatic stages of Hantavirus cardiopulmonary syndrome=== | |||
On the basis of symptoms, cardiopulmonary syndrome caused by hantavirus infection is divided into the following stages:<ref name="pmid8004332">{{cite journal |vauthors=Levy H, Simpson SQ |title=Hantavirus pulmonary syndrome |journal=Am. J. Respir. Crit. Care Med. |volume=149 |issue=6 |pages=1710–3 |year=1994 |pmid=8004332 |doi=10.1164/ajrccm.149.6.8004332 |url=}}</ref><ref name="pmid28120221">{{cite journal |vauthors=Jiang H, Zheng X, Wang L, Du H, Wang P, Bai X |title=Hantavirus infection: a global zoonotic challenge |journal=Virol Sin |volume=32 |issue=1 |pages=32–43 |year=2017 |pmid=28120221 |doi=10.1007/s12250-016-3899-x |url=}}</ref><ref name="pmid12521363">{{cite journal |vauthors=Lednicky JA |title=Hantaviruses. a short review |journal=Arch. Pathol. Lab. Med. |volume=127 |issue=1 |pages=30–5 |year=2003 |pmid=12521363 |doi=10.1043/0003-9985(2003)127<30:>2.0.CO;2 |url=}}</ref><ref name="pmid22553984">{{cite journal |vauthors=Sargianou M, Watson DC, Chra P, Papa A, Starakis I, Gogos C, Panos G |title=Hantavirus infections for the clinician: from case presentation to diagnosis and treatment |journal=Crit. Rev. Microbiol. |volume=38 |issue=4 |pages=317–29 |year=2012 |pmid=22553984 |doi=10.3109/1040841X.2012.673553 |url=}}</ref> | |||
#Prodormal or febrile stage (3-5 days) : It may include | |||
#*[[Fever]] | |||
#*[[Headache]] | |||
#*[[Malaise]] | |||
#*[[Myalgia]] | |||
#*[[Abdominal discomfort]] | |||
#Cardiopulmonary phase (5-7 days): | |||
#*[[Cough]] | |||
#*[[Dyspnea]] | |||
#*[[Chest pain]] | |||
#*[[Cyanosis]] | |||
#*[[Shock]] | |||
#Polyuric phase (2-3 days): | |||
#*Onset of [[diuresis]] | |||
#*Clinical improvement | |||
#Convalescent phase (months to years): | |||
#*[[Fatigue]] | |||
#*[[Weakness]] | |||
#*Impaired cognitive function | |||
==References== | |||
{{Reflist|2}} | |||
{{WH}} | |||
{{WikiDoc Sources}} | |||
[[Category:Viral diseases]] | |||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Needs content]] | |||
[[Category:Emergency mdicine]] | |||
[[Category:Up-To-Date]] | |||
[[Category:Infectious disease]] | [[Category:Infectious disease]] | ||
[[Category:Nephrology]] | |||
[[Category:Cardiology]] | |||
[[Category:Pulmonology]] |
Latest revision as of 21:57, 29 July 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]
Overview
The symptoms of hantavirus infection may include sudden fever, prostration, myalgia, and abdominal discomfort. Pulmonary and hemorrhagic symptoms may also arise in severe disease.
History and symptoms
History
Patient usually presents with history of flu-like illness. History of rodent or rodent dropping contact may be helpful.[1]
Common symptoms
The common symptoms of hantavirus infection are:[2]
Less common symptoms
In severe disease (cardiopulmonary or hemorrhagic fever), hantavirus infection can cause the following symptoms:The common symptoms of hantavirus infection are:[2]
- Dry cough
- Rapidly increasing dyspnea
- Petechiae
- Inflammatory symptoms of the eye
- Acute myopia
- Altered mental status
- Hypotension
Symptomatic stages of Hantavirus hemorrhagic fever with renal syndrome
On the basis of symptoms, hemorrhagic fever with renal syndrome caused by hantavirus infection is divided into the following stages:[2][3][4]
- Prodormal or Febrile phase(3-5 days):It may include
- Hemorrhagic phase(1-2 days): It may include
- Flushing of the face
- Injection of the conjunctiva
- Bleeding from mucous membranes
- Petechial rash
- Nausea and vomiting
- Hypotension
- Confusion
- Cold skin
- Oliguric phase (3-5 days):
- Decreased urine output which may result in renal failure
- Resolution of petechiae and flushing
- Polyuric phase:
- Onset of diuresis
- Clinical improvement
- Convalescent phase (weeks to months):
- Muscle weakness
- Hyposthenuria
- Polyuria
Symptomatic stages of Hantavirus cardiopulmonary syndrome
On the basis of symptoms, cardiopulmonary syndrome caused by hantavirus infection is divided into the following stages:[1][2][3][4]
- Prodormal or febrile stage (3-5 days) : It may include
- Cardiopulmonary phase (5-7 days):
- Polyuric phase (2-3 days):
- Onset of diuresis
- Clinical improvement
- Convalescent phase (months to years):
References
- ↑ 1.0 1.1 Levy H, Simpson SQ (1994). "Hantavirus pulmonary syndrome". Am. J. Respir. Crit. Care Med. 149 (6): 1710–3. doi:10.1164/ajrccm.149.6.8004332. PMID 8004332.
- ↑ 2.0 2.1 2.2 2.3 Jiang H, Zheng X, Wang L, Du H, Wang P, Bai X (2017). "Hantavirus infection: a global zoonotic challenge". Virol Sin. 32 (1): 32–43. doi:10.1007/s12250-016-3899-x. PMID 28120221.
- ↑ 3.0 3.1 Lednicky JA (2003). "Hantaviruses. a short review". Arch. Pathol. Lab. Med. 127 (1): 30–5. doi:10.1043/0003-9985(2003)127<30:>2.0.CO;2. PMID 12521363.
- ↑ 4.0 4.1 Sargianou M, Watson DC, Chra P, Papa A, Starakis I, Gogos C, Panos G (2012). "Hantavirus infections for the clinician: from case presentation to diagnosis and treatment". Crit. Rev. Microbiol. 38 (4): 317–29. doi:10.3109/1040841X.2012.673553. PMID 22553984.