Strongyloidiasis other diagnostic studies: Difference between revisions

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{{Strongyloidiasis}}
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==Overview==
Upper and lower [[Endoscopy|GI endoscopy]], [[skin biopsy]], and [[Bronchoalveolar lavage|BAL]] fluid examination are some other diagnostic tests that are employed in diagnosing strongyloidiasis when there is a negative stool exam.


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==Other diagnostic tests==
Upper and lower [[Endoscopy|GI endoscopy]], [[skin biopsy]], and [[Bronchoalveolar lavage|BAL]] fluid examination are some other diagnostic tests that are employed in diagnosing strongyloidiasis when there is a negative stool exam.<ref name="pmid21509240">{{cite journal |vauthors=Al-Sajee DM, Al-Hamdani A |title=A case of gastric and duodenal strongyloidiasis |journal=Sultan Qaboos Univ Med J |volume=10 |issue=2 |pages=262–5 |year=2010 |pmid=21509240 |pmc=3074720 |doi= |url=}}</ref><ref name="pmid17940124">{{cite journal |vauthors=Segarra-Newnham M |title=Manifestations, diagnosis, and treatment of Strongyloides stercoralis infection |journal=Ann Pharmacother |volume=41 |issue=12 |pages=1992–2001 |year=2007 |pmid=17940124 |doi=10.1345/aph.1K302 |url=}}</ref>
{| class="wikitable"
!Test
!Findings
|-
|Upper GI [[endoscopy]]
|
* Typically worms are found in the proximal part of the [[small intestine]]
* Edematous and [[erythematous]] [[mucosa]] with larva on biopsy
|-
|[[BAL]]/ Sputum examination
|
*Larvae can be detected by simple wet-mount in fluid collected by [[BAL]]
|-
|[[Skin biopsy]]
|
* Obtain specimens from the [[purpuric]] eruptions
* [[Edema]], extravasated [[red blood cells]] (RBCs), and some [[lymphocytes]] in the superficial [[dermis]].
* The larvae range in size from 9 to 15 µm.
|-
|[[CSF]] ([[CNS]] involvement)
|
* Findings similar to [[Bacterial meningitis MRI|bacterial meningitis]]
* Negative [[gram stain]]
* A wet mount preparation may reveal ''S stercoralis'' larvae.
|-
|Duodenal aspiration
|
*[[Duodenal]] aspirate is more sensitive than [[stool examination]], and [[duodenal]] [[biopsy]] may reveal [[parasites]] in the [[gastric]] crypts, in the [[duodenal]] glands, or [[eosinophilic]] infiltration in the [[lamina propria]].
*The [[duodenal]] fluid can be examined using techniques such as the Enterotest string or [[duodenal]] aspiration.​
|}


==References==
==References==


{{Reflist|2}}
{{Reflist|2}}
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Latest revision as of 00:19, 30 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]

Overview

Upper and lower GI endoscopy, skin biopsy, and BAL fluid examination are some other diagnostic tests that are employed in diagnosing strongyloidiasis when there is a negative stool exam.

Other diagnostic tests

Upper and lower GI endoscopy, skin biopsy, and BAL fluid examination are some other diagnostic tests that are employed in diagnosing strongyloidiasis when there is a negative stool exam.[1][2]

Test Findings
Upper GI endoscopy
BAL/ Sputum examination
  • Larvae can be detected by simple wet-mount in fluid collected by BAL
Skin biopsy
CSF (CNS involvement)
Duodenal aspiration

References

  1. Al-Sajee DM, Al-Hamdani A (2010). "A case of gastric and duodenal strongyloidiasis". Sultan Qaboos Univ Med J. 10 (2): 262–5. PMC 3074720. PMID 21509240.
  2. Segarra-Newnham M (2007). "Manifestations, diagnosis, and treatment of Strongyloides stercoralis infection". Ann Pharmacother. 41 (12): 1992–2001. doi:10.1345/aph.1K302. PMID 17940124.

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