Trichomoniasis other diagnostic studies: Difference between revisions
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==Overview== | |||
Another diagnostic test that may be helpful in the diagnosis of trichomoniasis is the whiff test.<ref name="pmid23322080">{{cite journal| author=Coleman JS, Gaydos CA, Witter F| title=Trichomonas vaginalis vaginitis in obstetrics and gynecology practice: new concepts and controversies. | journal=Obstet Gynecol Surv | year= 2013 | volume= 68 | issue= 1 | pages= 43-50 | pmid=23322080 | doi=10.1097/OGX.0b013e318279fb7d | pmc=3586271 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23322080 }} </ref> | |||
==Other diagnostic tests== | |||
Another diagnostic test that may be helpful in the diagnosis of trichomoniasis is the whiff test. | |||
===Whiff test=== | |||
Vaginal infection with trichomonas vaginalis alters the vaginal pH from [[acidic]] to basic. The whiff test is based on the addition of 10% [[potassium hydroxide]] to [[vaginal]] [[secretions]]. [[Vaginal]] pH >4.5 gives off a strong, fishy odor based on the presence of amines.<ref name="pmid23322080">{{cite journal| author=Coleman JS, Gaydos CA, Witter F| title=Trichomonas vaginalis vaginitis in obstetrics and gynecology practice: new concepts and controversies. | journal=Obstet Gynecol Surv | year= 2013 | volume= 68 | issue= 1 | pages= 43-50 | pmid=23322080 | doi=10.1097/OGX.0b013e318279fb7d | pmc=3586271 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23322080 }} </ref> | |||
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===The Solana trichomonas assay (Quidel)=== | |||
Another rapid test for the qualitative detection of ''T. vaginalis'' [[DNA]] and can yield results <40 minutes after specimen collection. This assay is FDA cleared for diagnosing ''T. vaginalis'' from female vaginal and urine specimens from [[asymptomatic]] and [[symptomatic]] women with [[sensitivity]] >98%, compared with [[NAAT]] for vaginal specimens, and >92% for [[urine]] specimens<ref name="urlSTI Treatment Guidelines">{{cite web |url=https://www.cdc.gov/std/treatment-guidelines/default.htm |title=STI Treatment Guidelines |format= |work= |accessdate=}}</ref> | |||
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===The Osom trichomonas rapid test (Sekisui Diagnostics)=== | |||
An [[antigen]]-detection [[test]] that uses immunochromatographic [[capillary]] flow dipstick technology by using clinician-obtained vaginal specimens. Results are available in approximately 10–15 minutes, with sensitivities of 82%–95% and specificity of 97%–100%, compared with wet mount, culture, and transcription-mediated amplification<ref name="urlSTI Treatment Guidelines" /> | |||
===The Amplivue trichomonas assay (Quidel)=== | |||
Another rapid test providing qualitative detection of ''T.'' ''vaginalis'' that has been FDA cleared for vaginal specimens from [[symptomatic]] and [[asymptomatic]] women, with [[sensitivity]] of 90.7% and [[specificity]] of 98.9%, compared with [[NAAT]]. <ref name="urlSTI Treatment Guidelines" /> | |||
The Osom assay and the Affirm VP III test is not FDA cleared for use with specimens from men.<ref name="urlSTI Treatment Guidelines" /><ref name="urlwww.cdc.gov">{{cite web |url=https://www.cdc.gov/std/treatment-guidelines/STI-Guidelines-2021.pdf |title=www.cdc.gov |format= |work= |accessdate=}}</ref> | |||
==References== | ==References== | ||
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[[Category: | [[Category:Gynecology]] | ||
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[[Category:Emergency mdicine]] | |||
[[Category:Disease]] | [[Category:Disease]] | ||
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[[Category:Infectious disease]] | [[Category:Infectious disease]] | ||
Latest revision as of 14:35, 17 September 2021
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aysha Anwar, M.B.B.S[2]
Overview
Another diagnostic test that may be helpful in the diagnosis of trichomoniasis is the whiff test.[1]
Other diagnostic tests
Another diagnostic test that may be helpful in the diagnosis of trichomoniasis is the whiff test.
Whiff test
Vaginal infection with trichomonas vaginalis alters the vaginal pH from acidic to basic. The whiff test is based on the addition of 10% potassium hydroxide to vaginal secretions. Vaginal pH >4.5 gives off a strong, fishy odor based on the presence of amines.[1]
The Solana trichomonas assay (Quidel)
Another rapid test for the qualitative detection of T. vaginalis DNA and can yield results <40 minutes after specimen collection. This assay is FDA cleared for diagnosing T. vaginalis from female vaginal and urine specimens from asymptomatic and symptomatic women with sensitivity >98%, compared with NAAT for vaginal specimens, and >92% for urine specimens[2]
The Osom trichomonas rapid test (Sekisui Diagnostics)
An antigen-detection test that uses immunochromatographic capillary flow dipstick technology by using clinician-obtained vaginal specimens. Results are available in approximately 10–15 minutes, with sensitivities of 82%–95% and specificity of 97%–100%, compared with wet mount, culture, and transcription-mediated amplification[2]
The Amplivue trichomonas assay (Quidel)
Another rapid test providing qualitative detection of T. vaginalis that has been FDA cleared for vaginal specimens from symptomatic and asymptomatic women, with sensitivity of 90.7% and specificity of 98.9%, compared with NAAT. [2]
The Osom assay and the Affirm VP III test is not FDA cleared for use with specimens from men.[2][3]
References
- ↑ 1.0 1.1 Coleman JS, Gaydos CA, Witter F (2013). "Trichomonas vaginalis vaginitis in obstetrics and gynecology practice: new concepts and controversies". Obstet Gynecol Surv. 68 (1): 43–50. doi:10.1097/OGX.0b013e318279fb7d. PMC 3586271. PMID 23322080.
- ↑ 2.0 2.1 2.2 2.3 "STI Treatment Guidelines".
- ↑ "www.cdc.gov" (PDF).