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==Overview==
A blood test indicating [[eosinophilia]], elevated muscle enzymes and anti trichinella [[IgG]] or muscle biopsy can identify trichinosis.<ref name="pmid19136437">{{cite journal| author=Gottstein B, Pozio E, Nöckler K| title=Epidemiology, diagnosis, treatment, and control of trichinellosis. | journal=Clin Microbiol Rev | year= 2009 | volume= 22 | issue= 1 | pages= 127-45, Table of Contents | pmid=19136437 | doi=10.1128/CMR.00026-08 | pmc=PMC2620635 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19136437  }} </ref><ref name="wiki1234">Trichinosis. Wikipedia. https://en.wikipedia.org/wiki/Trichinosis. Accessed on January 22, 2016</ref>


==Laboratory Findings==
==Laboratory Findings==
A [[blood test]] or [[muscle biopsy]] can identify trichinosis.  Stool studies can identify adult worms, with females being about 3 mm long and males about half that size.
'''Blood test''':<ref name="pmid19136437">{{cite journal| author=Gottstein B, Pozio E, Nöckler K| title=Epidemiology, diagnosis, treatment, and control of trichinellosis. | journal=Clin Microbiol Rev | year= 2009 | volume= 22 | issue= 1 | pages= 127-45, Table of Contents | pmid=19136437 | doi=10.1128/CMR.00026-08 | pmc=PMC2620635 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19136437  }} </ref>
Laboratory confirmation  of Trichinella infection is most  often by a blood test. In some cases a muscle biopsy may  be performed.
*''Eosinophilia'':
 
**Appears 2 or 5 weeks after infection
A  diagnosis of trichinellosis is made in patients whose signs and symptoms are compatible with  trichinellosis, have a positive laboratory test for Trichinella antibodies, and who can recall eating raw or  undercooked pork or wild game meat.
**It is related with severity of [[myalgia]]
**Higher levels among patients with [[neurological]] complications
**A great decrease of [[eosinophils]] in patients with complicated trichinosis is considered to be a bad indicator for the disease prognosis
*''Elevated muscle enzyme'':
**[[Creatinine phosphokinase]], [[lactate dehydrogenase]], and [[aldolase]]
**Appears 2 or 5 weeks after infection
*''Anti trichinella IgG:''
** 12 to 60 days after infection
**[[ELISA test|ELISA]], indirect fluorescent antibody test (IFA) and [[Western blot]] can be used to find anti-Trichinella [[IgG]]


==References==
==References==
{{reflist|2}}
{{reflist|2}}
[[Category:Conditions diagnosed by stool test]]
[[Category:Infectious disease]]
[[Category:Needs overview]]
[[Category:Needs content]]
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Latest revision as of 19:01, 18 September 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Danitza Lukac

Overview

A blood test indicating eosinophilia, elevated muscle enzymes and anti trichinella IgG or muscle biopsy can identify trichinosis.[1][2]

Laboratory Findings

Blood test:[1]

  • Eosinophilia:
    • Appears 2 or 5 weeks after infection
    • It is related with severity of myalgia
    • Higher levels among patients with neurological complications
    • A great decrease of eosinophils in patients with complicated trichinosis is considered to be a bad indicator for the disease prognosis
  • Elevated muscle enzyme:
  • Anti trichinella IgG:
    • 12 to 60 days after infection
    • ELISA, indirect fluorescent antibody test (IFA) and Western blot can be used to find anti-Trichinella IgG

References

  1. 1.0 1.1 Gottstein B, Pozio E, Nöckler K (2009). "Epidemiology, diagnosis, treatment, and control of trichinellosis". Clin Microbiol Rev. 22 (1): 127–45, Table of Contents. doi:10.1128/CMR.00026-08. PMC 2620635. PMID 19136437.
  2. Trichinosis. Wikipedia. https://en.wikipedia.org/wiki/Trichinosis. Accessed on January 22, 2016