Lymphogranuloma venereum history and symptoms: Difference between revisions
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{{Lymphogranuloma venereum}} | {{Lymphogranuloma venereum}} | ||
{{CMG}} | {{CMG}}; {{AE}} {{NRM}} | ||
==Overview== | |||
The most common symptom of primary LGV is a painless [[papule]] or [[ulcer]]. Secondary LGV is characterized by painful [[inguinal]] and/or [[femoral]] [[lymphadenopathy]], or [[Iliac]] and/or [[perirectal]] lymphadenopathy in patients with rectal exposure. [[Proctolcolits]] may also develop at this stage. Tertiary LGV symptoms include Lymphatic and rectal [[fibrosis]], genital [[elephantiasis]], esthiomene (chronic ulcerative disease of vulva), [[edema]], [[tenesmus]] and rectal discharge. LGV may spread systemically and cause the following symptoms: [[fever]], chills, [[malaise]], [[myalgia]], [[arthralgia]], [[arthritis]], [[hepatitis]] or [[perihepatitis]], and [[pneumonitis]]. | |||
==Symptoms== | ==Symptoms== | ||
===Primary LGV=== | |||
*Painless [[papule]] or [[ulcer]] | |||
*May be unnoticed by patient | |||
*[[Proctitis]] in patients with rectal exposure<ref name="Mabey2002">{{cite journal|last1=Mabey|first1=D|title=Lymphogranuloma venereum|journal=Sexually Transmitted Infections|volume=78|issue=2|year=2002|pages=90–92|issn=13684973|doi=10.1136/sti.78.2.90}}</ref> | |||
* | ===Secondary LGV=== | ||
*Painful [[inguinal]] and/or [[femoral]] [[lymphadenopathy]], usually unilateral<ref name="pmid25870512">{{cite journal| author=Ceovic R, Gulin SJ| title=Lymphogranuloma venereum: diagnostic and treatment challenges. | journal=Infect Drug Resist | year= 2015 | volume= 8 | issue= | pages= 39-47 | pmid=25870512 | doi=10.2147/IDR.S57540 | pmc=PMC4381887 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25870512 }} </ref> | |||
:*Lymphadenopathy may be characterized as fluctuant, suppurative [[buboes]] or nonsuppurative [[abscesses]] | |||
*[[Iliac]] and/or [[perirectal]] lymphadenopathy in patients with rectal exposure | |||
*Hemorrhagic [[proctocolitis]] | |||
* | *Lower abdominal or low-back pain<ref name="pmid24352129">{{cite journal| author=de Vries HJ, Zingoni A, White JA, Ross JD, Kreuter A| title=2013 European Guideline on the management of proctitis, proctocolitis and enteritis caused by sexually transmissible pathogens. | journal=Int J STD AIDS | year= 2013 | volume= 25 | issue= 7 | pages= 465-474 | pmid=24352129 | doi=10.1177/0956462413516100 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24352129 }} </ref> | ||
* | |||
===Tertiary LGV=== | |||
*Lymphatic and rectal [[fibrosis]]<ref name="pmid10449269">{{cite journal| author=Lynch CM, Felder TL, Schwandt RA, Shashy RG| title=Lymphogranuloma venereum presenting as a rectovaginal fistula. | journal=Infect Dis Obstet Gynecol | year= 1999 | volume= 7 | issue= 4 | pages= 199-201 | pmid=10449269 | doi=10.1155/S1064744999000344 | pmc=PMC1784745 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10449269 }} </ref> | |||
*Lymphorroids ([[hemorrhoid]]-like swellings of lymphatics) | |||
*Chronic [[edema]] | |||
*Genital [[elephantiasis]]<ref name="Mabey2002"></ref> | |||
*Esthiomene (chronic ulcerative disease of [[vulva]]) | |||
*Frozen pelvis syndrome<ref name="pmid16355328">{{cite journal| author=Van der Bij AK, Spaargaren J, Morré SA, Fennema HS, Mindel A, Coutinho RA et al.| title=Diagnostic and clinical implications of anorectal lymphogranuloma venereum in men who have sex with men: a retrospective case-control study. | journal=Clin Infect Dis | year= 2006 | volume= 42 | issue= 2 | pages= 186-94 | pmid=16355328 | doi=10.1086/498904 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16355328 }} </ref> | |||
*[[Tenesmus]] | |||
*Bloody purulent rectal discharge | |||
*Rectal pain | |||
*[[Hyperplasia]] of intestinal and perirectal lymphatic tissue<ref name="pmid25870512"></ref> | |||
===Systemic Symptoms=== | |||
*[[Fever]] | |||
*Chills | |||
*[[Malaise]] | |||
*[[Myalgia]] | |||
*[[Arthralgia]] | |||
*[[Arthritis]] | |||
*[[Hepatitis]] or [[perihepatitis]] | |||
*[[Pneumonitis]] | |||
*Cardiac involvment (rare) | |||
*[[Aseptic meningitis]] (rare) | |||
*Ocular inflammatory disease (rare)<ref name="pmid25870512"></ref> | |||
==References== | ==References== | ||
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[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Gynecology]] | [[Category:Gynecology]] | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Nate Michalak, B.A.
Overview
The most common symptom of primary LGV is a painless papule or ulcer. Secondary LGV is characterized by painful inguinal and/or femoral lymphadenopathy, or Iliac and/or perirectal lymphadenopathy in patients with rectal exposure. Proctolcolits may also develop at this stage. Tertiary LGV symptoms include Lymphatic and rectal fibrosis, genital elephantiasis, esthiomene (chronic ulcerative disease of vulva), edema, tenesmus and rectal discharge. LGV may spread systemically and cause the following symptoms: fever, chills, malaise, myalgia, arthralgia, arthritis, hepatitis or perihepatitis, and pneumonitis.
Symptoms
Primary LGV
Secondary LGV
- Painful inguinal and/or femoral lymphadenopathy, usually unilateral[2]
- Iliac and/or perirectal lymphadenopathy in patients with rectal exposure
- Hemorrhagic proctocolitis
- Lower abdominal or low-back pain[3]
Tertiary LGV
- Lymphatic and rectal fibrosis[4]
- Lymphorroids (hemorrhoid-like swellings of lymphatics)
- Chronic edema
- Genital elephantiasis[1]
- Esthiomene (chronic ulcerative disease of vulva)
- Frozen pelvis syndrome[5]
- Tenesmus
- Bloody purulent rectal discharge
- Rectal pain
- Hyperplasia of intestinal and perirectal lymphatic tissue[2]
Systemic Symptoms
- Fever
- Chills
- Malaise
- Myalgia
- Arthralgia
- Arthritis
- Hepatitis or perihepatitis
- Pneumonitis
- Cardiac involvment (rare)
- Aseptic meningitis (rare)
- Ocular inflammatory disease (rare)[2]
References
- ↑ 1.0 1.1 Mabey, D (2002). "Lymphogranuloma venereum". Sexually Transmitted Infections. 78 (2): 90–92. doi:10.1136/sti.78.2.90. ISSN 1368-4973.
- ↑ 2.0 2.1 2.2 Ceovic R, Gulin SJ (2015). "Lymphogranuloma venereum: diagnostic and treatment challenges". Infect Drug Resist. 8: 39–47. doi:10.2147/IDR.S57540. PMC 4381887. PMID 25870512.
- ↑ de Vries HJ, Zingoni A, White JA, Ross JD, Kreuter A (2013). "2013 European Guideline on the management of proctitis, proctocolitis and enteritis caused by sexually transmissible pathogens". Int J STD AIDS. 25 (7): 465–474. doi:10.1177/0956462413516100. PMID 24352129.
- ↑ Lynch CM, Felder TL, Schwandt RA, Shashy RG (1999). "Lymphogranuloma venereum presenting as a rectovaginal fistula". Infect Dis Obstet Gynecol. 7 (4): 199–201. doi:10.1155/S1064744999000344. PMC 1784745. PMID 10449269.
- ↑ Van der Bij AK, Spaargaren J, Morré SA, Fennema HS, Mindel A, Coutinho RA; et al. (2006). "Diagnostic and clinical implications of anorectal lymphogranuloma venereum in men who have sex with men: a retrospective case-control study". Clin Infect Dis. 42 (2): 186–94. doi:10.1086/498904. PMID 16355328.