Aphthous ulcer natural history, complications and prognosis: Difference between revisions
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{{Template:Aphthous ulcer}} | {{Template:Aphthous ulcer}} | ||
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==Overview== | |||
The natural history, complications and prognosis of recurrent aphthous ulcers varies with disease severity. | |||
==Natural History== | ==Natural History== | ||
*The most common form, the minor, is characterized by ovoid or circular lesions, smaller than 1cm in diameter, in number that varies from 1 to 5, covered by a thin [[pseudomembrane]] of white-gray color. It spontaneously resolves after 10-14 days leaving no [[scar]]. | |||
*The major form is less common, present with ulcers larger than 1cm in diameter, being deeper and associated with [[dysphagia]]. It can last for several weeks and may leave [[scars]]. They often affect the [[lip]], [[tongue]] and [[soft palate]]. | |||
*The herpetiform form is rarer and presents with pinpoint ulcers that are small in size (0.1-0.2cm) that may be present in large numbers or coalesce forming large lesions. These lesions may take 7-14 days to resolve usually leaving a scar. It is not related to the [[HSV]].<ref name="pmid29924245">{{cite journal| author=Queiroz SIML, Silva MVAD, Medeiros AMC, Oliveira PT, Gurgel BCV, Silveira ÉJDD| title=Recurrent aphthous ulceration: an epidemiological study of etiological factors, treatment and differential diagnosis. | journal=An Bras Dermatol | year= 2018 | volume= 93 | issue= 3 | pages= 341-346 | pmid=29924245 | doi=10.1590/abd1806-4841.20186228 | pmc=6001102 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29924245 }} </ref> | |||
==Complications== | ==Complications== | ||
*Complications are rare, and mostly due to associated diseases than the ulcers. The more severe forms of the disease may cause scarring. | |||
==Prognosis== | ==Prognosis== | ||
Aphthous ulcers usually heal on their own. The pain usually decreases in a few days. Other symptoms disappear in 10 to 14 days. | *Aphthous ulcers usually heal on their own. The pain usually decreases in a few days. Other symptoms disappear in 10 to 14 days. | ||
*Prognosis of the associated medical conditions is highly variable and should be assessed individually. | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
[[Category: | [[Category:Disease]] | ||
[[Category: | [[Category:Up-To-Date]] | ||
[[Category: | [[Category:Immunology]] | ||
[[Category:Otolaryngology]] | [[Category:Otolaryngology]] | ||
Latest revision as of 20:08, 12 January 2021
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: José Eduardo Riceto Loyola Junior, M.D.[2]
Overview
The natural history, complications and prognosis of recurrent aphthous ulcers varies with disease severity.
Natural History
- The most common form, the minor, is characterized by ovoid or circular lesions, smaller than 1cm in diameter, in number that varies from 1 to 5, covered by a thin pseudomembrane of white-gray color. It spontaneously resolves after 10-14 days leaving no scar.
- The major form is less common, present with ulcers larger than 1cm in diameter, being deeper and associated with dysphagia. It can last for several weeks and may leave scars. They often affect the lip, tongue and soft palate.
- The herpetiform form is rarer and presents with pinpoint ulcers that are small in size (0.1-0.2cm) that may be present in large numbers or coalesce forming large lesions. These lesions may take 7-14 days to resolve usually leaving a scar. It is not related to the HSV.[1]
Complications
- Complications are rare, and mostly due to associated diseases than the ulcers. The more severe forms of the disease may cause scarring.
Prognosis
- Aphthous ulcers usually heal on their own. The pain usually decreases in a few days. Other symptoms disappear in 10 to 14 days.
- Prognosis of the associated medical conditions is highly variable and should be assessed individually.
References
- ↑ Queiroz SIML, Silva MVAD, Medeiros AMC, Oliveira PT, Gurgel BCV, Silveira ÉJDD (2018). "Recurrent aphthous ulceration: an epidemiological study of etiological factors, treatment and differential diagnosis". An Bras Dermatol. 93 (3): 341–346. doi:10.1590/abd1806-4841.20186228. PMC 6001102. PMID 29924245.