Japanese encephalitis natural history, complications and prognosis: Difference between revisions
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{{Japanese encephalitis}} | {{Japanese encephalitis}} | ||
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==Overview== | |||
If left untreated, 50% of patients with Japanese encephalitis may progress to develop severe [[neurological]] deficits, such as [[deafness]], [[hemiparesis]], and [[aphasia]]. Common complications of Japanese encephalitis include [[seizure]]s, [[coma]], and [[spastic paralysis]]. Prognosis is generally poor. Approximately 20-30% of patients progress to [[mortality]]. Among patients who survive, approximately 50% suffer severe [[neurological]], [[cognitive]], or [[psychological]] deficits. | |||
==Natural History== | |||
If left untreated, 50% of patients with Japanese encephalitis may progress to develop severe [[neurological]] deficits, such as [[deafness]], [[hemiparesis]], and [[aphasia]].<ref name="pmid22993280">{{cite journal| author=Khandaker G, Zurynski Y, Buttery J, Marshall H, Richmond PC, Dale RC et al.| title=Neurologic complications of influenza A(H1N1)pdm09: surveillance in 6 pediatric hospitals. | journal=Neurology | year= 2012 | volume= 79 | issue= 14 | pages= 1474-81 | pmid=22993280 | doi=10.1212/WNL.0b013e31826d5ea7 | pmc=PMC4098823 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22993280 }} </ref><ref name=Mandell1> M.D. JE, Dolin R, Blaser MJ. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, Expert Consult Premium Edition. Saunders; 2014.</ref> | |||
==Complications== | |||
Common complications of Japanese encephalitis include:<ref name=WHOJaEncephFact> Japanese encephalitis - Fact sheet No 386. World Health Organization (WHO) (2015) http://www.who.int/mediacentre/factsheets/fs386/en/ Accessed on April 12, 2016</ref><ref name=CDCClinical> Japanese Encephalitis, Clinical and Laboratory Evaluation. Centers for Disease Control and Prevention (2015). http://www.cdc.gov/japaneseencephalitis/healthcareproviders/healthcareproviders-clinlabeval.html Accessed on April 14, 2016. </ref> | |||
*[[Seizure]]s | |||
*[[Coma]] | |||
*[[Disorientation]] | |||
*[[Spastic paralysis]] | |||
==Prognosis== | ==Prognosis== | ||
Prognosis is generally poor. Approximately 20-30% of patients progress to [[mortality]]. Among patients who survive, approximately 50% suffer severe [[neurological]], [[cognitive]], or [[psychological]] deficits.<ref name="pmid22993280">{{cite journal| author=Khandaker G, Zurynski Y, Buttery J, Marshall H, Richmond PC, Dale RC et al.| title=Neurologic complications of influenza A(H1N1)pdm09: surveillance in 6 pediatric hospitals. | journal=Neurology | year= 2012 | volume= 79 | issue= 14 | pages= 1474-81 | pmid=22993280 | doi=10.1212/WNL.0b013e31826d5ea7 | pmc=PMC4098823 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22993280 }} </ref><ref name=WHOJaEncephFact> Japanese encephalitis - Fact sheet No 386. World Health Organization (WHO) (2015) http://www.who.int/mediacentre/factsheets/fs386/en/ Accessed on April 12, 2016</ref> | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
[[Category:FinalQCRequired]] | |||
[[Category:Neurology]] | |||
{{WS}} | |||
{{WH}} | {{WH}} | ||
Latest revision as of 18:06, 18 September 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anthony Gallo, B.S. [2]
Overview
If left untreated, 50% of patients with Japanese encephalitis may progress to develop severe neurological deficits, such as deafness, hemiparesis, and aphasia. Common complications of Japanese encephalitis include seizures, coma, and spastic paralysis. Prognosis is generally poor. Approximately 20-30% of patients progress to mortality. Among patients who survive, approximately 50% suffer severe neurological, cognitive, or psychological deficits.
Natural History
If left untreated, 50% of patients with Japanese encephalitis may progress to develop severe neurological deficits, such as deafness, hemiparesis, and aphasia.[1][2]
Complications
Common complications of Japanese encephalitis include:[3][4]
Prognosis
Prognosis is generally poor. Approximately 20-30% of patients progress to mortality. Among patients who survive, approximately 50% suffer severe neurological, cognitive, or psychological deficits.[1][3]
References
- ↑ 1.0 1.1 Khandaker G, Zurynski Y, Buttery J, Marshall H, Richmond PC, Dale RC; et al. (2012). "Neurologic complications of influenza A(H1N1)pdm09: surveillance in 6 pediatric hospitals". Neurology. 79 (14): 1474–81. doi:10.1212/WNL.0b013e31826d5ea7. PMC 4098823. PMID 22993280.
- ↑ M.D. JE, Dolin R, Blaser MJ. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, Expert Consult Premium Edition. Saunders; 2014.
- ↑ 3.0 3.1 Japanese encephalitis - Fact sheet No 386. World Health Organization (WHO) (2015) http://www.who.int/mediacentre/factsheets/fs386/en/ Accessed on April 12, 2016
- ↑ Japanese Encephalitis, Clinical and Laboratory Evaluation. Centers for Disease Control and Prevention (2015). http://www.cdc.gov/japaneseencephalitis/healthcareproviders/healthcareproviders-clinlabeval.html Accessed on April 14, 2016.