Oral candidiasis risk factors: Difference between revisions

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==Overview==
Uncontrolled [[diabetes]] are more likely to get oral thrush, because the extra glucose in [[saliva]] acts as a substrate for ''[[Candida]]''. High doses of [[antibiotics]] or extended use of [[antibiotics]] also increases the risk of oral thrush. [[Antibiotics]] kill [[bacterial flora]] that compete with candida. People with [[Dentures|poorly fitting dentures]] are also more likely to get thrush.


==Risk Factors==
==Risk Factors==
*Thrush is commonly seen in infants.
*It is not considered abnormal in infants unless it lasts longer than 2 weeks.
*People who have [[Diabetes|uncontrolled diabetes]] are more likely to get oral thrush because the extra sugar in [[saliva]] acts as a substrate for ''[[Candida]].''
*High doses of [[antibiotics]] or extended use of [[antibiotics]] also increases the risk of oral thrush. [[Antibiotics]] kill [[bacterial flora]] that compete with [[candida]].
*People with poorly fitting [[dentures]] are also more likely to get thrush.


Thrush is commonly seen in infants. It is not considered abnormal in infants unless it lasts longer than a couple of weeks. [[Candida]] can also cause yeast infections in the [[vagina]]. People who have [[diabetes]] and had high blood sugar levels are more likely to get thrush in the mouth (oral thrush), because the extra sugar in your [[saliva]] acts like food for [[Candida]]. Taking high doses of [[antibiotics]] or taking [[antibiotics]] for a long time also increases the risk of oral thrush. [[Antibiotics]] kill some of the healthy bacteria that help keep [[Candida]] from growing too much. People with poorly fitting dentures are also more likely to get thrush.
===At Risk Individuals<ref name="pmid26679628">{{cite journal |vauthors=Pappas PG, Kauffman CA, Andes DR, Clancy CJ, Marr KA, Ostrosky-Zeichner L, Reboli AC, Schuster MG, Vazquez JA, Walsh TJ, Zaoutis TE, Sobel JD |title=Clinical Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of America |journal=Clin. Infect. Dis. |volume=62 |issue=4 |pages=e1–50 |year=2016 |pmid=26679628 |pmc=4725385 |doi=10.1093/cid/civ933 |url=}}</ref>===
 
*People with an [[immune deficiency]] (e.g. as a result of [[AIDS]]/[[HIV]] or [[chemotherapy]] treatment)
Invasive disease occurs in critically ill patients in intensive-care units, in persons with severe [[granulocytopenia]], and in hematopoietic stem cell and organ transplant recipients.
* [[Newborn]] babies
 
* [[Dentures|Denture]] users
===At Risk Individuals===
* Poorly controlled [[diabetes]]
* [[Newborn]] babies.
* As a side effect of medication, most commonly having taken [[antibiotic]]s. Inhaled [[corticosteroids]] for treatment of lung conditions (e.g, [[asthma]] or [[COPD]]) may also result in oral candidiasis which may be reduced by regularly rinsing the mouth with water after taking the medication.
* Denture users.
* People with poor [[nutrition]], specifically [[Vitamin A deficiency|vitamin A]], [[Iron deficiency anemia|iron]] and [[Folate deficiency|folate deficiencies]]
* Poorly controlled [[diabetes]].
* People with an [[immune deficiency]] (e.g. as a result of [[AIDS]]/[[HIV]] or [[chemotherapy]] treatment)
* As a side effect of medication, most commonly having taken [[antibiotic]]s. Inhaled [[corticosteroid]]s for treatment of lung conditions (e.g, [[Asthma]] or [[COPD]]) may also result in oral candidiasis which may be reduced by regularly rinsing the mouth with water after taking the medication.
* Women undergoing hormonal changes, like [[pregnancy]] or those on [[birth control pills]]
* People with poor [[nutrition]], specifically vitamin A, iron and folate deficiencies.
* [[Organ transplantation]] patients
* People with an [[immune deficiency]] (e.g. as a result of [[AIDS]]/[[HIV]] or [[chemotherapy]] treatment).
* Women undergoing hormonal changes, like pregnancy or those on birth control pills
* People who perform cunnilingus or fellatio on a sexual partner who has [[thrush]].
* Organ transplantation patients.


==References==
==References==
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[[Category:Needs overview]]
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[[Category:Disease]]
[[Category:Fungal diseases]]
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[[Category:Gastroenterology]]
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[[Category:Emergency mdicine]]
[[Category:Up-To-Date]]
[[Category:Infectious disease]]
[[Category:Infectious disease]]
[[Category:Signs and symptoms]]
[[Category:Otolaryngology]]
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[[Category:Pediatrics]]
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[[Category:Immunology]]

Latest revision as of 23:00, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Ahmed Younes M.B.B.CH [2]

Overview

Uncontrolled diabetes are more likely to get oral thrush, because the extra glucose in saliva acts as a substrate for Candida. High doses of antibiotics or extended use of antibiotics also increases the risk of oral thrush. Antibiotics kill bacterial flora that compete with candida. People with poorly fitting dentures are also more likely to get thrush.

Risk Factors

At Risk Individuals[1]

References

  1. Pappas PG, Kauffman CA, Andes DR, Clancy CJ, Marr KA, Ostrosky-Zeichner L, Reboli AC, Schuster MG, Vazquez JA, Walsh TJ, Zaoutis TE, Sobel JD (2016). "Clinical Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of America". Clin. Infect. Dis. 62 (4): e1–50. doi:10.1093/cid/civ933. PMC 4725385. PMID 26679628.

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