Epilepsy natural history, complications and prognosis: Difference between revisions
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__NOTOC__ | |||
{{Epilepsy}} | {{Epilepsy}} | ||
{{CMG}} {{AE}} {{ | |||
{{CMG}}; {{AE}} {{Fs}} | |||
==Overview== | ==Overview== | ||
If left untreated, 23% to 71% of patients with a single unprovoked [[seizure]] may experience it again within 2 years. After the second unprovoked [[seizure]], the chance of having another [[seizure]] increase to 73%. Recurrent [[Seizure|seizures]] with no underlying illness emphasis on epilepsy diagnosis. Common complications of epilepsy include: [[Status epilepticus]], sudden unexpected death, submersion Injury, dental injury, [[Burn|burns]], [[Bone fracture|fractures]], head injury, soft tissue injury and motor vehicle accidents. | |||
== Natural History, Complications, and Prognosis == | |||
=== Natural History === | |||
* If left untreated, 23% to 71% of patients with a single unprovoked [[seizure]] may experience it again within 2 years. | |||
* After the second unprovoked [[seizure]], the chance of having another [[seizure]] increase to 73%. | |||
* Recurrent [[Seizure|seizures]] with no underlying illness emphasis on epilepsy diagnosis. | |||
* In contrast to adolescent onset epilepsy syndromes most of the childhood onset epilepsy such as benign childhood epilepsy with centrotemporal spikes will go to [[Remission (medicine)|remission]]. | |||
* There is no evidence demonstrating the effect of medical therapy on natural history of epilepsy.<ref>{{cite book | last = Samuels | first = Martin | title = Samuels's Manual of neurologic therapeutics | publisher = Wolters Kluwer Health | location = Philadelphia | year = 2017 | isbn = 9781496360311 }}</ref> | |||
* | |||
=== Complications === | |||
* Common complications of epilepsy include: | |||
** [[Status epilepticus]]<ref name=":0">{{cite book | last = Mattle | first = Heinrich | title = Fundamentals of neurology : an illustrated guide | publisher = Thieme | location = Stuttgart New York | year = 2017 | isbn = 9783131364524 }}</ref> | |||
** Sudden unexpected death<ref>{{cite book | last = Samuels | first = Martin | title = Samuels's Manual of neurologic therapeutics | publisher = Wolters Kluwer Health | location = Philadelphia | year = 2017 | isbn = 9781496360311 }}</ref> | |||
** Submersion Injury | |||
** Dental injury<ref name="pmid9118849">{{cite journal |vauthors=Buck D, Baker GA, Jacoby A, Smith DF, Chadwick DW |title=Patients' experiences of injury as a result of epilepsy |journal=Epilepsia |volume=38 |issue=4 |pages=439–44 |date=April 1997 |pmid=9118849 |doi= |url=}}</ref> | |||
** [[Burn|Burns]]<ref name="pmid14692910">{{cite journal |vauthors=van den Broek M, Beghi E |title=Morbidity in patients with epilepsy: type and complications: a European cohort study |journal=Epilepsia |volume=45 |issue=1 |pages=71–6 |date=January 2004 |pmid=14692910 |doi= |url=}}</ref> | |||
** [[Bone fracture|Fractures]]<ref name="pmid12697142">{{cite journal |vauthors=Pack AM, Olarte LS, Morrell MJ, Flaster E, Resor SR, Shane E |title=Bone mineral density in an outpatient population receiving enzyme-inducing antiepileptic drugs |journal=Epilepsy Behav |volume=4 |issue=2 |pages=169–74 |date=April 2003 |pmid=12697142 |doi= |url=}}</ref> | |||
** Head injury | |||
** Soft tissue injury<ref name="pmid12199734">{{cite journal |vauthors=Beghi E, Cornaggia C |title=Morbidity and accidents in patients with epilepsy: results of a European cohort study |journal=Epilepsia |volume=43 |issue=9 |pages=1076–83 |date=September 2002 |pmid=12199734 |doi= |url=}}</ref> | |||
** Motor vehicle accidents<ref name="pmid8404737">{{cite journal |vauthors=Hansotia P, Broste SK |title=Epilepsy and traffic safety |journal=Epilepsia |volume=34 |issue=5 |pages=852–8 |date=1993 |pmid=8404737 |doi= |url=}}</ref> | |||
** [[Epileptic Heart|Epileptic heart]]<ref name="VerrierPang2020">{{cite journal|last1=Verrier|first1=Richard L.|last2=Pang|first2=Trudy D.|last3=Nearing|first3=Bruce D.|last4=Schachter|first4=Steven C.|title=The Epileptic Heart: Concept and clinical evidence|journal=Epilepsy & Behavior|volume=105|year=2020|pages=106946|issn=15255050|doi=10.1016/j.yebeh.2020.106946}}</ref> | |||
** [[Sudden cardiac death]] | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
[[Category:Neurological disorders]] | [[Category:Neurological disorders]] | ||
[[Category:Neurology]] | [[Category:Neurology]] | ||
Line 13: | Line 39: | ||
[[Category:Pediatrics]] | [[Category:Pediatrics]] | ||
[[Category:Emergency medicine]] | [[Category:Emergency medicine]] | ||
Latest revision as of 23:55, 13 January 2021
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Fahimeh Shojaei, M.D.
Overview
If left untreated, 23% to 71% of patients with a single unprovoked seizure may experience it again within 2 years. After the second unprovoked seizure, the chance of having another seizure increase to 73%. Recurrent seizures with no underlying illness emphasis on epilepsy diagnosis. Common complications of epilepsy include: Status epilepticus, sudden unexpected death, submersion Injury, dental injury, burns, fractures, head injury, soft tissue injury and motor vehicle accidents.
Natural History, Complications, and Prognosis
Natural History
- If left untreated, 23% to 71% of patients with a single unprovoked seizure may experience it again within 2 years.
- After the second unprovoked seizure, the chance of having another seizure increase to 73%.
- Recurrent seizures with no underlying illness emphasis on epilepsy diagnosis.
- In contrast to adolescent onset epilepsy syndromes most of the childhood onset epilepsy such as benign childhood epilepsy with centrotemporal spikes will go to remission.
- There is no evidence demonstrating the effect of medical therapy on natural history of epilepsy.[1]
Complications
- Common complications of epilepsy include:
- Status epilepticus[2]
- Sudden unexpected death[3]
- Submersion Injury
- Dental injury[4]
- Burns[5]
- Fractures[6]
- Head injury
- Soft tissue injury[7]
- Motor vehicle accidents[8]
- Epileptic heart[9]
- Sudden cardiac death
References
- ↑ Samuels, Martin (2017). Samuels's Manual of neurologic therapeutics. Philadelphia: Wolters Kluwer Health. ISBN 9781496360311.
- ↑ Mattle, Heinrich (2017). Fundamentals of neurology : an illustrated guide. Stuttgart New York: Thieme. ISBN 9783131364524.
- ↑ Samuels, Martin (2017). Samuels's Manual of neurologic therapeutics. Philadelphia: Wolters Kluwer Health. ISBN 9781496360311.
- ↑ Buck D, Baker GA, Jacoby A, Smith DF, Chadwick DW (April 1997). "Patients' experiences of injury as a result of epilepsy". Epilepsia. 38 (4): 439–44. PMID 9118849.
- ↑ van den Broek M, Beghi E (January 2004). "Morbidity in patients with epilepsy: type and complications: a European cohort study". Epilepsia. 45 (1): 71–6. PMID 14692910.
- ↑ Pack AM, Olarte LS, Morrell MJ, Flaster E, Resor SR, Shane E (April 2003). "Bone mineral density in an outpatient population receiving enzyme-inducing antiepileptic drugs". Epilepsy Behav. 4 (2): 169–74. PMID 12697142.
- ↑ Beghi E, Cornaggia C (September 2002). "Morbidity and accidents in patients with epilepsy: results of a European cohort study". Epilepsia. 43 (9): 1076–83. PMID 12199734.
- ↑ Hansotia P, Broste SK (1993). "Epilepsy and traffic safety". Epilepsia. 34 (5): 852–8. PMID 8404737.
- ↑ Verrier, Richard L.; Pang, Trudy D.; Nearing, Bruce D.; Schachter, Steven C. (2020). "The Epileptic Heart: Concept and clinical evidence". Epilepsy & Behavior. 105: 106946. doi:10.1016/j.yebeh.2020.106946. ISSN 1525-5050.