Dermatitis herpetiformis overview: Difference between revisions
No edit summary |
AmberJavaid (talk | contribs) |
||
(5 intermediate revisions by 3 users not shown) | |||
Line 1: | Line 1: | ||
__NOTOC__ | |||
{{Dermatitis herpetiformis}} | {{Dermatitis herpetiformis}} | ||
{{CMG}} {{AE}} {{VVS}} | {{CMG}} {{AE}} {{VVS}} | ||
==Overview== | ==Overview== | ||
[[ | |||
Dermatitis Herpetiformis (also called [[Duhring's disease]]), is a chronic itchy rash which is frequently associated with [[Celiac Disease]]. The rash is made of [[papules]] and [[vesicles]] which are present on different parts of the body mostly commonly on neck, trunk, buttocks and knees. It is an [[autoimmune]] mediated skin condition, which is IgA mediated reaction and is associated with [[gluten sensitivity]] of small bowel. There is presence of [[antibodies]] which leads to positive serology test results. | |||
Dermatitis herpetiformis is associated with high prevalence of other [[autoimmune diseases]]. | |||
==Historical Perspective== | |||
==Classification== | |||
==Pathophysiology== | |||
==Causes== | |||
==Differentiating Dermatitis Herpetiformis from Other Diseases== | |||
==Epidemiology and Demographics== | |||
==Risk Factors== | ==Risk Factors== | ||
Dermatitis herpetiformis usually begins in people age 20 and older, although children may sometimes be affected. It is seen in both men and women. | Dermatitis herpetiformis usually begins in people age 20 and older, although children may sometimes be affected. It is seen in both men and women. | ||
==Natural History, Complications and Prognosis== | |||
==Diagnosis== | ==Diagnosis== | ||
Line 13: | Line 32: | ||
Dermatitis herpetiformis breakouts are usually extremely itchy. In many people the [[Vesicle (Biology)|vesicles]] or [[papule]]s appear on the elbows, knees, back, and buttocks (pressure points). It may also present as a patch of red skin with little water blisters scattered about. It is a systemic condition; the unpredictable skin rash may appear or be exacerbated by any irritation such as dry skin, scratching or clothing that is rough or scratchy. The fact that the rash is most prevalent at pressure points (where clothing rubs the most) may be why the symptoms sometimes appear to be symmetrical. | Dermatitis herpetiformis breakouts are usually extremely itchy. In many people the [[Vesicle (Biology)|vesicles]] or [[papule]]s appear on the elbows, knees, back, and buttocks (pressure points). It may also present as a patch of red skin with little water blisters scattered about. It is a systemic condition; the unpredictable skin rash may appear or be exacerbated by any irritation such as dry skin, scratching or clothing that is rough or scratchy. The fact that the rash is most prevalent at pressure points (where clothing rubs the most) may be why the symptoms sometimes appear to be symmetrical. | ||
===Physical Examination=== | |||
===Laboratory Findings=== | ===Laboratory Findings=== | ||
A skin [[biopsy]] and direct [[immunofluorescence]] test of the skin are performed in most cases; doctors may additionally recommend a biopsy of the intestines. | A skin [[biopsy]] and direct [[immunofluorescence]] test of the skin are performed in most cases; doctors may additionally recommend a biopsy of the intestines. | ||
===CT Findings=== | |||
===MRI Findings=== | |||
===Other Imaging Findings=== | |||
==Treatment== | ==Treatment== | ||
Line 23: | Line 50: | ||
[[Dapsone]], an antibiotic, may help the majority of patients. A strict [[gluten-free diet]] will also be recommended to help control the disease. Adherence to this diet may eliminate the need for medications and prevent later complications. | [[Dapsone]], an antibiotic, may help the majority of patients. A strict [[gluten-free diet]] will also be recommended to help control the disease. Adherence to this diet may eliminate the need for medications and prevent later complications. | ||
===Surgery=== | |||
===Prevention=== | |||
==References== | ==References== | ||
Line 28: | Line 59: | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Immunology]] | [[Category:Immunology]] | ||
[[Category:Allergology]] | [[Category:Allergology]] | ||
[[Category:Dermatology]] | [[Category:Dermatology]] | ||
[[Category:Skin diseases]] | [[Category:Skin diseases]] | ||
[[Category:Needs content]] | [[Category:Needs content]] |
Latest revision as of 00:38, 7 February 2021
Dermatitis herpetiformis Microchapters |
Differentiating Dermatitis herpetiformis from other Diseases |
---|
Diagnosis |
Treatment |
Case Studies |
Dermatitis herpetiformis overview On the Web |
American Roentgen Ray Society Images of Dermatitis herpetiformis overview |
Risk calculators and risk factors for Dermatitis herpetiformis overview |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Vishnu Vardhan Serla M.B.B.S. [2]
Overview
Dermatitis Herpetiformis (also called Duhring's disease), is a chronic itchy rash which is frequently associated with Celiac Disease. The rash is made of papules and vesicles which are present on different parts of the body mostly commonly on neck, trunk, buttocks and knees. It is an autoimmune mediated skin condition, which is IgA mediated reaction and is associated with gluten sensitivity of small bowel. There is presence of antibodies which leads to positive serology test results.
Dermatitis herpetiformis is associated with high prevalence of other autoimmune diseases.
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Dermatitis Herpetiformis from Other Diseases
Epidemiology and Demographics
Risk Factors
Dermatitis herpetiformis usually begins in people age 20 and older, although children may sometimes be affected. It is seen in both men and women.
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms
Dermatitis herpetiformis breakouts are usually extremely itchy. In many people the vesicles or papules appear on the elbows, knees, back, and buttocks (pressure points). It may also present as a patch of red skin with little water blisters scattered about. It is a systemic condition; the unpredictable skin rash may appear or be exacerbated by any irritation such as dry skin, scratching or clothing that is rough or scratchy. The fact that the rash is most prevalent at pressure points (where clothing rubs the most) may be why the symptoms sometimes appear to be symmetrical.
Physical Examination
Laboratory Findings
A skin biopsy and direct immunofluorescence test of the skin are performed in most cases; doctors may additionally recommend a biopsy of the intestines.
CT Findings
MRI Findings
Other Imaging Findings
Treatment
Medical Therapy
Dapsone, an antibiotic, may help the majority of patients. A strict gluten-free diet will also be recommended to help control the disease. Adherence to this diet may eliminate the need for medications and prevent later complications.