First degree AV block causes: Difference between revisions
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{{First degree AV block}} | {{First degree AV block}} | ||
{{CMG}}; {{AE}} {{CZ}}; {{RT}} | {{CMG}}; {{AE}} {{CZ}}; {{RT}} | ||
==Overview== | ==Overview== | ||
Common causes of [[first-degree AV block]] include [[ischemic heart disease]], [[congenital heart disease]], [[electrolyte]] abnormalities (particularly [[hypokalemia]] and [[hypomagnesemia]]), [[inflammation]], [[infections]] ([[endocarditis]], [[rheumatic fever]], [[Chagas disease]], [[Lyme disease]], [[diphtheria]]), [[drugs]] ([[antiarrhythmic ]] Ia, Ic, II, III, IV and [[digoxin]], [[β-blockers]], [[calcium channel blockers]] ), [[infiltrative diseases]] ([[sarcoidosis]]), [[collagen vascular diseases]] ([[SLE]], [[rheumatoid arthritis]], [[scleroderma]]), idiopathic degenerative diseases ([[Lenegre]] and [[Lev diseases]]) and [[neuromuscular disorders]] and increased [[vagal tone]] in younger [[patients]]. | |||
==Causes== | ==Causes== | ||
===Life Threatening Causes=== | ===Life Threatening Causes=== | ||
Life-threatening conditions | Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated. | ||
* [[Acute myocardial infarction]] | *[[Acute myocardial infarction]] | ||
* [[Acute rheumatic fever]] | *[[Acute rheumatic fever]] | ||
* [[Bacterial endocarditis]] | *[[Bacterial endocarditis]] | ||
* [[Myocarditis]] | *[[Myocarditis]] | ||
===Common Causes=== | ===Common Causes=== | ||
* [[Hyperkalemia]] | *[[Hyperkalemia]] | ||
* [[Hyperthyroidism]] | *[[Hyperthyroidism]] | ||
* [[vagus nerve|Increased vagal tone]] (e.g. sleep, athletes) | *[[Hypothyroidism]] | ||
* [[Ischemic heart disease]] | *[[vagus nerve|Increased vagal tone]] (e.g. [[sleep]], athletes) | ||
* Medications ( e.g. [[adenosine]], [[amiodarone]], [[beta-blockers]], [[diltiazem]], [[procainamide]], [[verapamil]]) | *[[Ischemic heart disease]] | ||
*Medications ( e.g. [[adenosine]], [[amiodarone]], [[beta-blockers]], [[diltiazem]], [[procainamide]], [[verapamil]]) | |||
===Causes by Organ System=== | ===Causes by Organ System=== | ||
{|style="width:80%; height:100px" border="1" | {|style="width:80%; height:100px" border="1" | ||
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular''' | |style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular''' | ||
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" |[[Acute myocardial infarction]], [[ | |style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | [[Acute myocardial infarction]], [[acute rheumatic fever]], [[ASD]], [[dilated cardiomyopathy]], [[Ebstein's anomaly]], [[Carotid sinus hypersensitivity|hypersensitive carotid sinus syndrome]], [[hypertension]], [[hypertrophic cardiomyopathy]], [[Lev's disease]], [[myocardial bridging]], [[myocarditis]], [[Aortic valve replacement|post aortic valve replacement]], [[catheter ablation|post catheter ablation for arrhythmias]], [[ventricular septal defect surgery|post closure of a ventricular septal defect]], [[mitral valve replacement|post mitral valve replacement]], [[tetralogy of Fallot]], [[endocardial cushion defect]], [[transposition of the great vessels]], [[valvular heart disease]], [[VSD]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Drug Side Effect''' | | '''Drug Side Effect''' | ||
|bgcolor="Beige"| [[ | |bgcolor="Beige"| [[Amiodarone]], [[beta-blockers]], [[digitalis]], [[calcium channel blockers]], [[cholinesterase inhibitor|cholinesterase inhibitors]], [[disopyramide]], [[dofetilide]], [[dolasetron]], [[donepezil]], [[eslicarbazepine acetate]], [[fesoterodine]], [[fingolimod]], [[flecainide]], [[ibutilide]], [[lacosamide]], [[magnesium]], [[paliperidone]], [[pramipexole]], [[procainamide]], [[propafenone]], [[propoxyphene]], [[quinidine]], [[sotalol]], [[terodiline]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Endocrine''' | | '''Endocrine''' | ||
|bgcolor="Beige"| [[Hyperthyroidism]], [[myxedema]], [[periodic paralysis|thyrotoxic periodic | |bgcolor="Beige"| [[Hyperthyroidism]], [[myxedema]], [[periodic paralysis|thyrotoxic periodic paralysis]], [[hypothyroidism]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Genetic''' | | '''Genetic''' | ||
|bgcolor="Beige"| [[Emery-Dreifuss muscular dystrophy]], [[Fabry disease]], [[glycogenosis type 2b]], hereditary neuromuscular | |bgcolor="Beige"| [[Emery-Dreifuss muscular dystrophy]], [[Fabry disease]], [[glycogenosis type 2b]], [[Neuromuscular disease|hereditary neuromuscular disease]], [[Kearns-Sayre syndrome]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Infectious Disease''' | | '''Infectious Disease''' | ||
|bgcolor="Beige"| [[Acute rheumatic fever]], [[Chagas disease]], [[diphtheria]], [[Lyme disease]], [[myocarditis]], [[ | |bgcolor="Beige"| [[Acute rheumatic fever]], [[Chagas disease]], [[diphtheria]], [[Lyme disease]], [[myocarditis]], [[neonatal lupus erythematosus]], [[protozoa|protozoal infection]], [[sarcoidosis]], [[SLE]], [[tuberculosis]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Musculoskeletal / Ortho''' | | '''Musculoskeletal / Ortho''' | ||
|bgcolor="Beige"| [[Ankylosing spondylitis]], [[ | |bgcolor="Beige"| [[Ankylosing spondylitis]], [[Neuromuscular disease|hereditary neuromuscular disease]], [[Kearns-Sayre syndrome]], [[mitochondrial disease|mitochondrial genome inherited conditions]], [[muscular dystrophy]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Renal / Electrolyte''' | | '''Renal / Electrolyte''' | ||
|bgcolor="Beige"| [[ | |bgcolor="Beige"| [[Hyperkalemia]], [[hypokalemia]] | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Rheum / Immune / Allergy''' | | '''Rheum / Immune / Allergy''' | ||
|bgcolor="Beige"| [[Ankylosing spondylitis]], [[dermatomyositis]], [[ | |bgcolor="Beige"| [[Ankylosing spondylitis]], [[dermatomyositis]], [[rheumatoid arthritis]], [[scleroderma]], [[SLE]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Miscellaneous''' | | '''Miscellaneous''' | ||
|bgcolor="Beige"| [[Amyloidosis]], [[degenerative diseases]], | |bgcolor="Beige"| [[Amyloidosis]], [[degenerative diseases]], [[vagus nerve|enhanced vagal tone]], [[PR interval|normal variants]] | ||
|- | |- | ||
|} | |} | ||
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{{col-begin|width=80%}} | {{col-begin|width=80%}} | ||
{{col-break|width=33%}} | {{col-break|width=33%}} | ||
* [[Acute | *[[Acute myocardial infarction]] | ||
*[[Acute rheumatic fever]] | |||
* [[Acute rheumatic fever]] | *[[Amyloidosis]] | ||
*[[Ankylosing spondylitis]] | |||
* [[Amyloidosis]] | *[[ASD]] | ||
*[[Bacterial endocarditis]] | |||
* [[Ankylosing spondylitis]] | *[[Beta-blockers]] | ||
*[[Calcific aortic stenosis]] | |||
* [[ASD]] | *[[Calcium channel blockers]] | ||
*[[Cardiac glycosides]] | |||
* [[Bacterial endocarditis]] | *[[Cardiac tumors]] | ||
*[[Chagas disease]] | |||
* [[Beta-blockers]] | *[[Cholinesterase inhibitors]] | ||
*[[Clonidine]] | |||
* [[Calcific aortic stenosis]] | *[[Degenerative diseases]] | ||
*[[Dermatomyositis]] | |||
* [[Calcium channel blockers]] | *[[Digitalis]] | ||
*[[Digoxin]] | |||
* [[Cardiac glycosides]] | *[[Dilated cardiomyopathy]] | ||
*[[Diltiazem]] | |||
* [[Cardiac tumors]] | *[[Diphtheria]] | ||
*[[Disopyramide]] | |||
* [[Chagas disease]] | *[[Dolasetron]] | ||
*[[Donepezil]] | |||
* [[Cholinesterase inhibitors]] | *[[Ebstein anomaly]] | ||
*[[Ebstein's anomaly]] | |||
* [[Clonidine]] | *[[Electrolyte disturbances]] | ||
*[[Emery-Dreifuss muscular dystrophy]] | |||
* [[Degenerative diseases]] | *[[vagus nerve|Enhanced vagal tone in athletes]] | ||
* [[Dermatomyositis]] | |||
* [[Digitalis]] | |||
* [[Digoxin]] | |||
* [[Dilated cardiomyopathy]] | |||
* [[Diltiazem]] | |||
* [[Diphtheria]] | |||
* [[Disopyramide]] | |||
* [[Dolasetron]] | |||
* [[Donepezil]] | |||
* [[Ebstein anomaly]] | |||
* [[Ebstein's anomaly]] | |||
* [[Electrolyte disturbances]] | |||
* [[Emery-Dreifuss muscular dystrophy | |||
* | |||
{{col-break|width=33%}} | {{col-break|width=33%}} | ||
* [[Fabry disease]] | *[[Eslicarbazepine acetate]] | ||
*[[Fabry disease]] | |||
* [[Fesoterodine]] | *[[Fesoterodine]] | ||
*[[Fingolimod]] | |||
* [[Fingolimod]] | *[[Glycogenosis type 2b]] | ||
*[[HCM]] | |||
* [[Glycogenosis type 2b]] | * [[Neuromuscular disease|Hereditary neuromuscular disease]] | ||
*[[Hodgkin lymphoma]] | |||
* [[HCM]] | *[[Hyperkalaemia]] | ||
*[[Carotid sinus hypersensitivity|Hypersensitive carotid sinus syndrome]] | |||
* Hereditary neuromuscular | *[[Hyperthyroidism]] | ||
*[[Hypokalaemia]] | |||
* [[Hodgkin lymphoma]] | *[[Hypothermia]] | ||
*[[Ibutilide]] | |||
* [[Hyperkalaemia]] | *[[Ischaemic heart disease]] | ||
*[[Kearns-Sayre syndrome]] | |||
* [[Carotid sinus hypersensitivity|Hypersensitive carotid | *[[Labetalol]] | ||
*[[Lacosamide]] | |||
* [[Hyperthyroidism]] | *[[Lanatoside C]] | ||
*[[Lenegre's disease]] | |||
* [[Hypokalaemia]] | *[[Lev's disease]] | ||
*[[Lyme disease]] | |||
* [[Hypothermia]] | *[[Mitochondrial DNA|Mitochondrial genome inherited conditions]] | ||
*[[Multiple myeloma]] | |||
* [[Ibutilide]] | *[[Muscular dystrophy]] | ||
*[[Myocardial bridging]] | |||
*[[Myocarditis]] | |||
*[[Myotonic dystrophy]] | |||
*[[Myxedema]] | |||
* [[Ischaemic heart disease]] | |||
* [[Kearns-Sayre syndrome]] | |||
* [[Labetalol]] | |||
* [[Lacosamide]] | |||
* [[Lanatoside C]] | |||
* [[Lenegre's disease]] | |||
* [[Lev's disease]] | |||
* [[Lyme disease]] | |||
* [[Mitochondrial DNA|Mitochondrial genome inherited conditions]] | |||
* [[Multiple myeloma]] | |||
* [[Muscular dystrophy]] | |||
* [[Myocardial bridging]] | |||
* [[Myocarditis]] | |||
* [[Myotonic dystrophy]] | |||
* [[Myxedema]] | |||
{{col-break|width=33%}} | {{col-break|width=33%}} | ||
*[[Neonatal lupus erythematosus]] | |||
*[[prolonged PR interval|Normal variants of PR prolongation]] | |||
*[[Paliperidone]] | |||
* [[ | *[[aortic valve replacement|Post aortic valve replacement ]] | ||
*[[catheter ablation|Post catheter ablation for arrhythmias]] | |||
* [[ | *[[Ventricular septal defect surgery|Post closure of a ventricular septal defect]] | ||
*[[mitral valve replacement|Post mitral valve replacement]] | |||
* [[Paliperidone]] | *[[Procainamide]] | ||
*[[Propoxyphene]] | |||
* [[aortic valve replacement|Post aortic valve replacement ]] | *[[Propranolol]] | ||
*[[Protozoa|Protozoal infection]] | |||
* [[catheter ablation|Post catheter ablation for arrhythmias]] | *[[Quinidine]] | ||
*[[Quinine]] | |||
* [[Ventricular septal defect surgery|Post closure of a ventricular septal defect]] | *[[Rheumatic fever|Rheumatic mitral valve disease]] | ||
*[[Sarcoidosis]] | |||
* [[mitral valve replacement|Post mitral valve replacement]] | *[[SLE]] | ||
*[[Systemic sclerosis]] | |||
* [[Procainamide ]] | *[[Terodiline]] | ||
*[[Tetralogy of Fallot]] | |||
* [[Propoxyphene]] | *[[periodic paralysis|Thyrotoxic periodic paralysis]] | ||
*[[Tolterodine]] | |||
* [[Propranolol]] | *[[Transposition of the great vessels]] | ||
*[[vagus nerve|Vagal maneuvers]] | |||
* [[Protozoa|Protozoal infection]] | *[[Valsalva maneuver]] | ||
*[[Valvular heart disease]] | |||
* [[Quinidine]] | *[[Verapamil]] | ||
*[[VSD]] | |||
* [[Quinine]] | *[[sex linkage|X-linked inherited conditions]] | ||
* [[Rheumatic fever|Rheumatic mitral valve disease]] | |||
* [[Sarcoidosis]] | |||
* [[SLE]] | |||
* [[Systemic sclerosis]] | |||
* [[Terodiline]] | |||
* [[Tetralogy of | |||
* [[periodic paralysis|Thyrotoxic periodic paralysis]] | |||
* [[Tolterodine]] | |||
* [[Transposition of the great vessels]] | |||
* [[vagus nerve|Vagal maneuvers]] | |||
* [[Valsalva | |||
* [[Valvular heart disease]] | |||
* [[Verapamil]] | |||
* [[VSD]] | |||
* [[sex linkage|X-linked inherited conditions]] | |||
{{col-end}} | {{col-end}} | ||
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{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Cardiology]] | [[Category:Cardiology]] | ||
[[Category:Up-To-Date]] | [[Category:Up-To-Date]] | ||
[[Category:Up-To-Date cardiology]] | [[Category:Up-To-Date cardiology]] | ||
[[Category:Arrhythmia]] | [[Category:Arrhythmia]] | ||
[[Category:Electrophysiology]] | |||
[[Category:Disease]] | [[Category:Disease]] | ||
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Latest revision as of 04:51, 22 July 2021
First degree AV block Microchapters |
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First degree AV block causes On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2]; Raviteja Guddeti, M.B.B.S. [3]
Overview
Common causes of first-degree AV block include ischemic heart disease, congenital heart disease, electrolyte abnormalities (particularly hypokalemia and hypomagnesemia), inflammation, infections (endocarditis, rheumatic fever, Chagas disease, Lyme disease, diphtheria), drugs (antiarrhythmic Ia, Ic, II, III, IV and digoxin, β-blockers, calcium channel blockers ), infiltrative diseases (sarcoidosis), collagen vascular diseases (SLE, rheumatoid arthritis, scleroderma), idiopathic degenerative diseases (Lenegre and Lev diseases) and neuromuscular disorders and increased vagal tone in younger patients.
Causes
Life Threatening Causes
Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.
Common Causes
- Hyperkalemia
- Hyperthyroidism
- Hypothyroidism
- Increased vagal tone (e.g. sleep, athletes)
- Ischemic heart disease
- Medications ( e.g. adenosine, amiodarone, beta-blockers, diltiazem, procainamide, verapamil)