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| {{drugbox
| | #REDIRECT [[Nafcillin sodium]] |
| | IUPAC_name = 7-[(2-ethoxynaphthalen-1-yl) carbonylamino]- 3,3-dimethyl-6-oxo-2-thia-5-azabicyclo [ 3.2.0] heptane-4-carboxylic acid
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| | image = Nafcillin.svg
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| | CAS_number = 985-16-0
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| | ATC_prefix =
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| | ATC_suffix =
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| | PubChem = 8982
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| | DrugBank = APRD01130
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| | C = 21 | H = 22 | N = 2 | O = 5 | S = 1
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| | molecular_weight = 414.476 g/mol
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| | bioavailability =
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| | protein_bound = 90%
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| | metabolism = <30% [[hepatic]]
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| | elimination_half-life =
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| | excretion = Biliary and [[Kidney|renal]]
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| | pregnancy_category =
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| | legal_status =
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| | routes_of_administration = [[Intramuscular injection|IM]], [[Intravenous therapy|IV]]
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| }}
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| {{SI}}
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| '''Nafcillin sodium''' is a [[narrow-spectrum antibiotic|narrow spectrum]] [[beta-lactam antibiotic]] of the [[penicillin]] class. As a [[beta-lactamase]]-resistant penicillin, it is used to treat [[infections]] caused by [[Gram-positive]] [[bacteria]], particularly [[species]] of [[Staphylococci]], that are [[antibiotic resistance|resistant]] to other penicillins.
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| ==Side effects==
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| As with all penicillins, serious life-threatening [[allergy|allergic reactions]] can occur.
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| Milder side effects include:
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| * [[Nausea]] and [[vomiting]]
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| * [[Diarrhea]], often due to suppression of normal [[gastrointestinal]] bacteria. Occasionally, this leads to a more serious super-infection with an organism like [[Clostridium difficile]]
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| * [[Abdominal pain]]
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| * [[Yeast]] infections ([[Candidiasis|thrush]]) affecting the [[mouth]] and [[tongue]] or [[vagina]]
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| {{PenicillinAntiBiotics}}
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| [[Category: Beta-lactam antibiotics]]
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| {{WH}}
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| {{WikiDoc Sources}}
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