Rifapentine indications and usage: Difference between revisions

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Rifapentine should not be used as monotherapy in either the initial or the continuation phases of antituberculous treatment.<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = PRIFTIN (RIFAPENTINE) TABLET, FILM COATED [SANOFI-AVENTIS U.S. LLC] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=f768e337-a948-420a-9fbe-9be359c7a170 | publisher =  | date =  | accessdate = }}</ref>
Rifapentine should not be used as monotherapy in either the initial or the continuation phases of antituberculous treatment.<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = PRIFTIN (RIFAPENTINE) TABLET, FILM COATED [SANOFI-AVENTIS U.S. LLC] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=f768e337-a948-420a-9fbe-9be359c7a170 | publisher =  | date =  | accessdate = }}</ref>


==References==
==References==

Latest revision as of 16:35, 6 January 2014

Rifapentine
FDA Package Insert (PRIFTIN®)
Description
Clinical Pharmacology
Microbiology
Indications and Usage
Contraindications
Warnings and Precautions
Adverse Reactions
Overdosage
Dosage and Administration
How Supplied
Labels and Packages

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Chetan Lokhande, M.B.B.S [2]

Indications And Usage

Rifapentine is indicated for the treatment of pulmonary tuberculosis caused by Mycobacterium tuberculosis. Rifapentine must always be used in combination with one or more antituberculosis drugs to which the isolate is susceptible depending on the phase of treatment [see Dosage and Administration and Clinical Studies .

Limitations of Use

Rifapentine should not be used as a once weekly Continuation Phase regimen in combination with isoniazid in HIV seropositive patients with pulmonary tuberculosis because of a higher rate of failure and/or relapse documented with the presence of rifampin-resistant organisms [see Warnings and Precautions and Clinical Studies ].

Rifapentine has not been studied as part of the Initial Phase treatment regimen in HIV seropositive patients with pulmonary tuberculosis.

Rifapentine should not be used as monotherapy in either the initial or the continuation phases of antituberculous treatment.[1]

References

  1. "PRIFTIN (RIFAPENTINE) TABLET, FILM COATED [SANOFI-AVENTIS U.S. LLC]".

Adapted from the FDA Package Insert.