Halofantrine description: Difference between revisions
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==Description== | |||
Halfan (halofantrine hydrochloride) is an antimalarial drug available as tablets containing 250 mg of halofantrine hydrochloride (equivalent to 233 mg of the free base) for oral administration. | |||
The chemical name of halofantrine hydrochloride is 1,3-dichloro-α-[2-(dibutylamino) ethyl]- 6-(trifluoromethyl)-9-phenanthrene-methanol hydrochloride. | |||
The drug, a white to off-white crystalline compound, is practically insoluble in water. Halofantrine hydrochloride has a calculated molecular weight of 536.89. The empirical formula is C26H30Cl2F3NOüHCl and the structural formula is: | |||
Inactive ingredients are magnesium stearate, microcrystalline cellulose, povidone, pregelatinized starch, sodium starch glycolate and talc.<ref>{{Cite web | last = | first = | title = http://www.accessdata.fda.gov/drugsatfda_docs/label/2002/20250s7s8lbl.pdf | url = http://www.accessdata.fda.gov/drugsatfda_docs/label/2002/20250s7s8lbl.pdf | publisher = | date = | accessdate = }}</ref> | |||
<ref>{{Cite web | last = | first = | title = http://www.accessdata.fda.gov/drugsatfda_docs/label/2002/20250s7s8lbl.pdf | url = http://www.accessdata.fda.gov/drugsatfda_docs/label/2002/20250s7s8lbl.pdf | publisher = | date = | accessdate = }}</ref> | |||
==References== | ==References== | ||
Latest revision as of 02:48, 7 January 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Description
Halfan (halofantrine hydrochloride) is an antimalarial drug available as tablets containing 250 mg of halofantrine hydrochloride (equivalent to 233 mg of the free base) for oral administration.
The chemical name of halofantrine hydrochloride is 1,3-dichloro-α-[2-(dibutylamino) ethyl]- 6-(trifluoromethyl)-9-phenanthrene-methanol hydrochloride. The drug, a white to off-white crystalline compound, is practically insoluble in water. Halofantrine hydrochloride has a calculated molecular weight of 536.89. The empirical formula is C26H30Cl2F3NOüHCl and the structural formula is:
Inactive ingredients are magnesium stearate, microcrystalline cellulose, povidone, pregelatinized starch, sodium starch glycolate and talc.[1]
References
- ↑ "http://www.accessdata.fda.gov/drugsatfda_docs/label/2002/20250s7s8lbl.pdf" (PDF). External link in
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Adapted from the FDA Package Insert.