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| __NOTOC__
| | #redirect [[Sofosbuvir#Overdosage]] |
| {{Sofosbuvir}}
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| {{CMG}}
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| ==Overdosage==
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| The highest documented dose of sofosbuvir was a single supratherapeutic dose of sofosbuvir 1200 mg administered to 59 healthy subjects. In that trial, there were no untoward effects observed at this dose level, and adverse events were similar in frequency and severity to those reported in the placebo and sofosbuvir 400 mg treatment groups. The effects of higher doses are not known.
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| No specific antidote is available for overdose with SOVALDI. If overdose occurs the patient must be monitored for evidence of toxicity. Treatment of overdose with SOVALDI consists of general supportive measures including monitoring of vital signs as well as observation of the clinical status of the patient. A 4-hour hemodialysis session removed 18% of the administered dose.<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = SOVALDI (SOFOSBUVIR) TABLET, FILM COATED [GILEAD SCIENCES, INC.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=80beab2c-396e-4a37-a4dc-40fdb62859cf#nlm43685-7 | publisher = | date = | accessdate = 7 January 2014 }}</ref>
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| ==References==
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| {{Reflist}}
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| {{FDA}}
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| [[Category:Antiviral]] | |
| [[Category:Wikinfect]]
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