Luliconazole description: Difference between revisions
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{{CMG}}; {{AE}} {{AZ}} | {{CMG}}; {{AE}} {{AZ}} | ||
==Description== | |||
<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = LUZU (LULICONAZOLE) CREAM [MEDICIS PHARMACEUTICAL CORP.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=a7016010-ce43-4c09-8d21-aeb697ffed31 | publisher = | date = | accessdate = }}</ref> | LUZU (luliconazole) Cream, 1% contains 1% luliconazole, an azole antifungal agent, in a white cream for topical application. | ||
Luliconazole is (2E)-2-[(4R)-4-(2,4-dichlorophenyl)-1,3-dithiolan-2-ylidene]-2-imidazol-1-ylacetonitrile. Its structural formula is: | |||
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|[[File:Describtionluliconazole.JPG|600px|thumb]] | |||
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The molecular formula is C14H9Cl2N3S2 with a molecular weight of 354.28. Luliconazole is the R-enantiomer and contains one chiral center. The double bond adjacent to the dithiolane group is in the E configuration. | |||
LUZU Cream, 1% contains 10 mg of luliconazole per gram of cream in a vehicle consisting of benzyl alcohol, butylated hydroxytoluene, cetostearyl alcohol, isopropyl myristate, medium-chain triglycerides, methylparaben, polysorbate 60, propylene glycol, purified water, and sorbitan monostearate.<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = LUZU (LULICONAZOLE) CREAM [MEDICIS PHARMACEUTICAL CORP.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=a7016010-ce43-4c09-8d21-aeb697ffed31 | publisher = | date = | accessdate = }}</ref> | |||
==References== | ==References== | ||
Latest revision as of 15:34, 8 January 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [2]
Description
LUZU (luliconazole) Cream, 1% contains 1% luliconazole, an azole antifungal agent, in a white cream for topical application.
Luliconazole is (2E)-2-[(4R)-4-(2,4-dichlorophenyl)-1,3-dithiolan-2-ylidene]-2-imidazol-1-ylacetonitrile. Its structural formula is:
 |
The molecular formula is C14H9Cl2N3S2 with a molecular weight of 354.28. Luliconazole is the R-enantiomer and contains one chiral center. The double bond adjacent to the dithiolane group is in the E configuration.
LUZU Cream, 1% contains 10 mg of luliconazole per gram of cream in a vehicle consisting of benzyl alcohol, butylated hydroxytoluene, cetostearyl alcohol, isopropyl myristate, medium-chain triglycerides, methylparaben, polysorbate 60, propylene glycol, purified water, and sorbitan monostearate.[1]
References
Adapted from the FDA Package Insert.