Ofloxacin drug interactions: Difference between revisions
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Specific drug interaction studies have not been conducted with OCUFLOX® ophthalmic solution. However, the systemic administration of some quinolones has been shown to elevate plasma concentrations of theophylline, interfere with the metabolism of caffeine, and enhance the effects of the oral anticoagulant warfarin and its derivatives, and has been associated with transient elevations in serum creatinine in patients receiving cyclosporine concomitantly.<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = NOROXIN (NORFLOXACIN) TABLET, FILM COATED [MERCK SHARP & DOHME CORP.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=36087c76-5da9-4fab-e88f-da1d5a579d8e | publisher = | date = | accessdate = 8 January 2014 }}</ref> | Specific drug interaction studies have not been conducted with OCUFLOX® ophthalmic solution. However, the systemic administration of some [[quinolones]] has been shown to elevate plasma concentrations of theophylline, interfere with the metabolism of caffeine, and enhance the effects of the oral anticoagulant [[warfarin]] and its derivatives, and has been associated with transient elevations in serum [[creatinine]] in patients receiving [[cyclosporine]] concomitantly.<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = NOROXIN (NORFLOXACIN) TABLET, FILM COATED [MERCK SHARP & DOHME CORP.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=36087c76-5da9-4fab-e88f-da1d5a579d8e | publisher = | date = | accessdate = 8 January 2014 }}</ref> | ||
==References== | ==References== | ||
Latest revision as of 23:31, 8 January 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2]
Drug Interactions
Specific drug interaction studies have not been conducted with OCUFLOX® ophthalmic solution. However, the systemic administration of some quinolones has been shown to elevate plasma concentrations of theophylline, interfere with the metabolism of caffeine, and enhance the effects of the oral anticoagulant warfarin and its derivatives, and has been associated with transient elevations in serum creatinine in patients receiving cyclosporine concomitantly.[1]
References
- ↑ "NOROXIN (NORFLOXACIN) TABLET, FILM COATED [MERCK SHARP & DOHME CORP.]". Retrieved 8 January 2014.
Adapted from the FDA Package Insert.