Doxycycline calcium: Difference between revisions
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'''''For patient information, click <u>[[Doxycycline calcium (patient information)|here]]'''''</u>. | '''''For patient information, click <u>[[Doxycycline calcium (patient information)|here]]'''''</u>. | ||
{{CMG}} | {{CMG}}; {{AE}} {{MM}} | ||
==Overview== | ==Overview== | ||
'''Doxycycline''' ([[International Phonetic Alphabet|IPA]] is a [[tetracycline antibiotic]] which is commonly used to treat a variety of [[infection]]s. Under the brand name ''Vibramycin'', [[Pfizer]]'s doxycycline product received | '''Doxycycline''' ([[International Phonetic Alphabet|IPA]] is a [[tetracycline antibiotic]] which is commonly used to treat a variety of [[infection]]s. Under the brand name ''Vibramycin'', [[Pfizer]]'s doxycycline product received Food and Drug Administration (United States)|US Food and Drug Administration approval in 1967.<ref name=PackageInsert>{{cite web|title=Vibramycin. HUMAN PRESCRIPTION DRUG LABEL|url=http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=d6f98d3c-5a20-4cbf-9a9c-abef10b9e465#nlm34089-3|work=DailyMed|publisher=U.S. National Library of Medicine|accessdate=3 October 2013}}</ref> Other brand names include Monodox, Microdox, Periostat, Vibra-Tabs, Oracea, Doryx,<ref>{{cite news| url=http://www.bloomberg.com/news/2012-04-30/mylan-impax-win-ruling-in-doryx-generics-patent-case.html | work=Bloomberg | first1=David | last1=Voreacos | first2=Susan | last2=Decker | title=Mylan, Impax Win Ruling in Doryx Generics Patent Case | date=30 April 2012}}</ref> Vibrox, Adoxa, Doxyhexal, Doxylin, Doxoral, Doxy-1 and Atridox (topical doxycycline hyclate for [[periodontitis]]). | ||
==Category== | ==Category== | ||
Latest revision as of 00:20, 9 January 2014
For patient information, click here.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]
Overview
Doxycycline (IPA is a tetracycline antibiotic which is commonly used to treat a variety of infections. Under the brand name Vibramycin, Pfizer's doxycycline product received Food and Drug Administration (United States)|US Food and Drug Administration approval in 1967.[1] Other brand names include Monodox, Microdox, Periostat, Vibra-Tabs, Oracea, Doryx,[2] Vibrox, Adoxa, Doxyhexal, Doxylin, Doxoral, Doxy-1 and Atridox (topical doxycycline hyclate for periodontitis).
Category
US Brand Names
VIBRAMYCIN HYCLATE®
FDA Package Insert
Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Drug Interactions | Overdosage | Dosage and Administration | How Supplied | Labels and Packages
Mechanism of Action
As with related tetracycline antibiotics, demeclocycline acts by binding to the 30S and 50S ribosomal subunits, which impairs protein synthesis by bacteria. It is bacteriostatic (it impairs bacterial growth, but does not kill bacteria directly).
It is not completely understood why demeclocycline impairs the action of antidiuretic hormone, but is thought to block the binding of the hormone from its receptor.[3]
References
- ↑ "Vibramycin. HUMAN PRESCRIPTION DRUG LABEL". DailyMed. U.S. National Library of Medicine. Retrieved 3 October 2013.
- ↑ Voreacos, David; Decker, Susan (30 April 2012). "Mylan, Impax Win Ruling in Doryx Generics Patent Case". Bloomberg.
- ↑ De Troyer A, Demanet JC (1975). "Correction of antidiuresis by demeclocycline". N Engl J Med. 293 (18): 915–8. doi:10.1056/NEJM197510302931809. PMID 170519.