Methenamine mandelate: Difference between revisions

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==Overview==
==Overview==
Methenamine mandelate, USP, a urinary antibacterial agent, is the chemical combination of mandelic acid with methenamine. Methenamine mandelate, USP is available for oral use as film-coated tablets.  Methenamine mandelate, USP is indicated for the suppression or elimination of bacteriuria associated with pyelonephritis, cystitis, and other chronic urinary tract infections.<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = METHENAMINE MANDELATE TABLET [EDENBRIDGE PHARMACEUTICALS, LLC] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=cc299e8a-cf9a-4dc6-b6e6-972141e59296 | publisher =  | date =  | accessdate}}</ref>


==Category==
==Category==
[[Tetracycline]]
Urinary anti-infective


==US Brand Names==
==US Brand Names==
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'''  [[Methenamine mandelate description|Description]]'''
'''  [[Methenamine mandelate description|Description]]'''
'''| [[Methenamine mandelate clinical pharmacology|Clinical Pharmacology]]'''
'''| [[Methenamine mandelate clinical pharmacology|Clinical Pharmacology]]'''
'''| [[Methenamine mandelate microbiology|Microbiology]]'''
'''| [[Methenamine mandelate indications and usage|Indications and Usage]]'''
'''| [[Methenamine mandelate indications and usage|Indications and Usage]]'''
'''| [[Methenamine mandelate contraindications|Contraindications]]'''
'''| [[Methenamine mandelate contraindications|Contraindications]]'''
'''| [[Methenamine mandelate warnings and precautions|Warnings and Precautions]]'''
'''| [[Methenamine mandelate warnings and precautions|Warnings and Precautions]]'''
'''| [[Methenamine mandelate adverse reactions|Adverse Reactions]]'''
'''| [[Methenamine mandelate adverse reactions|Adverse Reactions]]'''
'''| [[Methenamine mandelate overdosage|Overdosage]]'''
'''| [[Methenamine mandelate dosage and administration|Dosage and Administration]]'''
'''| [[Methenamine mandelate dosage and administration|Dosage and Administration]]'''
'''| [[Methenamine mandelate how supplied|How Supplied]]'''
'''| [[Methenamine mandelate how supplied|How Supplied]]'''
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==Mechanism of Action==
==Mechanism of Action==
An acid urine is essential for antibacterial action, with maximum efficacy occurring at pH 5.5 or less.  In an acid urine, mandelic acid exerts its antibacterial action and also contributes to the acidification of the urine.<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = METHENAMINE MANDELATE TABLET [EDENBRIDGE PHARMACEUTICALS, LLC] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=cc299e8a-cf9a-4dc6-b6e6-972141e59296 | publisher =  | date =  | accessdate}}</ref>


==References==
==References==

Latest revision as of 09:21, 9 January 2014

Methenamine mandelate
METHENAMINE MANDELATE® FDA Package Insert
Description
Clinical Pharmacology
Indications and Usage
Contraindications
Warnings and Precautions
Adverse Reactions
Dosage and Administration
How Supplied
Labels and Packages

For patient information, click here.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]

Overview

Methenamine mandelate, USP, a urinary antibacterial agent, is the chemical combination of mandelic acid with methenamine. Methenamine mandelate, USP is available for oral use as film-coated tablets. Methenamine mandelate, USP is indicated for the suppression or elimination of bacteriuria associated with pyelonephritis, cystitis, and other chronic urinary tract infections.[1]

Category

Urinary anti-infective

US Brand Names

METHENAMINE MANDELATE®

FDA Package Insert

Description | Clinical Pharmacology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Dosage and Administration | How Supplied | Labels and Packages

Mechanism of Action

An acid urine is essential for antibacterial action, with maximum efficacy occurring at pH 5.5 or less. In an acid urine, mandelic acid exerts its antibacterial action and also contributes to the acidification of the urine.[1]

References

  1. 1.0 1.1 "METHENAMINE MANDELATE TABLET [EDENBRIDGE PHARMACEUTICALS, LLC]". Text " accessdate" ignored (help)