Atorvastatin contraindications: Difference between revisions

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__NOTOC__
#REDIRECT [[Atorvastatin#Contraindications]]
{{Atorvastatin}}
{{CMG}}; {{AE}} {{PB}}
 
[[Atherosclerosis]] is a chronic process and discontinuation of lipid lowering drugs during pregnancy should have little impact on the outcome of long-term therapy of [[primary hypercholesterolemia]].
 
[[Cholesterol]] and other products of [[cholesterol biosynthesis]] are essential components for fetal development (including synthesis of steroids and cell membranes). Since [[HMG-CoA reductase inhibitor]]s decrease cholesterol synthesis and possibly the synthesis of other biologically active substances derived from cholesterol, they may cause fetal harm when administered to pregnant women. Therefore, [[HMG-CoA reductase inhibitor]]s are contraindicated during pregnancy and in nursing mothers.<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = LIPITOR (ATORVASTATIN CALCIUM) TABLET, FILM COATED [PARKE-DAVIS DIV OF PFIZER INC] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=c6e131fe-e7df-4876-83f7-9156fc4e8228#nlm34089-3 | publisher =  | date =  | accessdate = }}</ref>
 
'''Atorvastatin should be administered to women of childbearing age only when such patients are highly unlikely to conceive and have been informed of the potential hazards.'''
 
'''If the patient becomes pregnant while taking this drug, therapy should be discontinued and the patient apprised of the potential hazard to the fetus.'''
 
==Contraindications of Atorvastatin==
 
===Active liver disease or unexplained persistent elevations of serum transaminases===
 
===Hypersensitivity to any component of this medication===
 
===Pregnancy and Lactation===
 
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{{FDA}}
 
==References==
{{Reflist}}
 
 
 
[[Category:Drugs]]

Latest revision as of 14:40, 22 July 2014