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| __NOTOC__
| | #REDIRECT [[Isosorbide mononitrate#Pharmacology]] |
| {{Isosorbide mononitrate
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| {{CMG}}; {{AE}} {{PB}}
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| Isosorbide Mononitrate (ISMN), an organic nitrate and the major biologically active metabolite of isosorbide dinitrate (ISDN), is a vasodilator with effects on both arteries and veins.
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| Each Isosorbide mononitrate extended-release tablet, for oral administration contains 30 mg, 60 mg or 120 mg of ISMN. In addition, each tablet contains the following inactive ingredients: carnauba wax, colloidal silicon dioxide, ethylcellulose, hypromellose, lactose, magnesium stearate, polyethylene glycol, polysorbate 80, titanium dioxide. The 30 mg tablet also contains D&D Red No. 27 aluminum lake, D&C Red No. 30 aluminum lake, FD&C Blue No. 2 aluminum lake, and FD&C Yellow No. 6 aluminum lake. The 60 mg tablet also contains D&C Yellow No. 10 aluminum lake and FD&C Blue No. 2 aluminum lake.
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| The molecular formula of ISMN is C6H9NO6 and the molecular weight is 191.14.
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| The chemical name for ISMN is 1,4:3,6-dianhydro-D-glucitol 5-nitrate; the compound has the following structural formula:
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| ISMN is a white, crystalline, odorless compound which is stable in air and in solution, has a melting point of about 90°C, and an optical rotation of +144° (2% in water, 20°C).
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| ISMN is freely soluble in water, ethanol, methanol, chloroform, ethyl acetate, and dichloromethane.
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| <ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = ISOSORBIDE MONONITRATE TABLET [ZYDUS PHARMACEUTICALS (USA) INC.] | url =http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=897a0327-25d4-4769-bd6a-0e674264017f | publisher = | date = | accessdate = 30 January 2014 }}</ref>
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| [[Image:Isosorbide_mononitrate1.jpg|thumb|widthpx| ]]
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| ==References==
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| {{Reflist|2}}
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| [[Category:Drugs]]
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