|
|
| (2 intermediate revisions by 2 users not shown) |
| Line 1: |
Line 1: |
| __NOTOC__
| | #REDIRECT [[Propranolol#Overdosage]] |
| {{Propranolol}}
| |
| {{CMG}}; {{AE}} {{AZ}}
| |
| | |
| ==Overdosage==
| |
| | |
| Propranolol is not significantly dialyzable. In the event of overdosage or exaggerated response, the following measures should be employed:
| |
| | |
| ===General===
| |
| | |
| If ingestion is or may have been recent, evacuate gastric contents, taking care to prevent [[pulmonary aspiration]].
| |
| | |
| ===Supportive Therapy===[[Hypotension]] and [[bradycardia]] have been reported following propranolol overdose and should be treated appropriately. Glucagon can exert potent inotropic and chronotropic effects and may be particularly useful for the treatment of hypotension or depressed myocardial function after a propranolol overdose. Glucagon should be administered as 50-150 mcg/kg intravenously followed by continuous drip of 1-5 mg/hour for positive chronotropic effect. Isoproterenol, dopamine or phosphodiesterase inhibitors may also be useful. Epinephrine, however, may provoke uncontrolled hypertension. Bradycardia can be treated with atropine or isoproterenol. Serious bradycardia may require temporary cardiac pacing.The electrocardiogram, pulse, blood pressure, neurobehavioral status and intake and output balance must be monitored. Isoproterenol and [[aminophylline]] may be used for [[bronchospasm]].<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = INDERAL LA (PROPRANOLOL HYDROCHLORIDE) CAPSULE, EXTENDED RELEASE [AKRIMAX PHARMACEUTICALS, LLC] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=fce692df-1e68-465e-8dda-0cb01320608c | publisher = | date = |accessdate = }}</ref>
| |
| ==References==
| |
| {{Reflist}}
| |
| | |
| {{FDA}}
| |
| | |
| [[Category:Drugs]]
| |