|
|
| Line 1: |
Line 1: |
| __NOTOC__
| | #REDIRECT [[Clonidine#Adverse Reactions]] |
| {{Clonidine}}
| |
| {{CMG}}; {{AE}} {{PB}}
| |
| | |
| '''''For patient information, click [[Clonidine (patient information)|here]]'''''.
| |
| | |
| ==Adverse Reactions==
| |
| Most adverse effects are mild and tend to diminish with continued therapy. The most frequent (which appear to be dose-related) are dry mouth, occurring in about 40 of 100 patients; drowsiness, about 33 in 100; dizziness, about 16 in 100; constipation and sedation, each about 10 in 100.
| |
| | |
| The following less frequent adverse experiences have also been reported in patients receiving CATAPRES tablets, but in many cases patients were receiving concomitant medication and a causal relationship has not been established.
| |
| | |
| ===Body as a Whole===
| |
| [[Fatigue]], [[fever]], [[headache]], [[pallor]], weakness, and withdrawal syndrome. Also reported were a weakly positive Coombs’ test and increased sensitivity to alcohol.
| |
| | |
| ===Cardiovascular===
| |
| [[Bradycardia]], [[congestive heart failure]], electrocardiographic abnormalities (i.e., sinus node arrest, [[junctional bradycardia]], high degree [[AV block]] and [[arrhythmias]]), orthostatic symptoms, palpitations, [[Raynaud’s phenomenon]], [[syncope]], and tachycardia. Cases of [[sinus bradycardia]] and [[atrioventricular block]] have been reported, both with and without the use of concomitant [[digitalis]].
| |
| | |
| ===Central Nervous System===
| |
| [[Agitation]], [[anxiety]], [[delirium]], [[delusional]] perception, [[hallucinations]] (including visual and auditory), [[insomnia]], mental [[depression]], [[nervousness]], other behavioral changes, [[paresthesia]], [[restlessness]], [[sleep disorder]], and vivid dreams or nightmares.
| |
| | |
| ===Dermatological===
| |
| [[Alopecia]], [[angioneurotic edema]], [[hives]], [[pruritus]], [[rash]], and [[urticaria]].
| |
| | |
| ===Gastrointestinal===
| |
| Abdominal pain, [[anorexia]], [[constipation]], [[hepatitis]], [[malaise]], mild transient abnormalities in liver function tests, [[nausea]], [[parotitis]], pseudo-obstruction (including colonic pseudo-obstruction), salivary gland pain, and [[vomiting]].
| |
| | |
| ===Genitourinary===
| |
| Decreased sexual activity, difficulty in micturition, erectile dysfunction, loss of libido, nocturia, and urinary retention.
| |
| | |
| ===Hematologic===
| |
| [[Thrombocytopenia]].
| |
| | |
| ===Metabolic===
| |
| [[Gynecomastia]], transient elevation of blood glucose or serum [[creatine phosphokinase]], and weight gain.
| |
| | |
| ===Musculoskeletal===
| |
| Leg cramps and muscle or joint pain.
| |
| | |
| ===Oro-otolaryngeal===
| |
| Dryness of the nasal mucosa.
| |
| | |
| ===Ophthalmological===
| |
| Accommodation disorder, blurred vision, burning of the eyes, decreased lacrimation, and dryness of eyes.<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = CATAPRES (CLONIDINE HYDROCHLORIDE) TABLET [BOEHRINGER INGELHEIM PHARMACEUTICALS INC.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=d7f569dc-6bed-42dc-9bec-940a9e6b090d | publisher = | date = | accessdate = 5 February 2014 }}</ref>
| |
| | |
| ==References==
| |
| | |
| {{Reflist|2}}
| |
| | |
| {{Antimigraine preparations}}
| |
|
| |
|
| | [[Category:Cardiovascular Drugs]] |
| [[Category:Drugs]] | | [[Category:Drugs]] |