|
|
| (2 intermediate revisions by one other user not shown) |
| Line 1: |
Line 1: |
| __NOTOC__
| | #REDIRECT [[Dobutamine#How Supplied]] |
| {{Dobutamine}}
| |
| {{CMG}}; {{AE}} {{AZ}}
| |
| | |
| ==Dosasage And Administration==
| |
| | |
| '''Note''' '''Do not add dobutamine injection to 5% Sodium Bicarbonate Injection or to any other strongly alkaline solution'''. Because of potential physical incompatibilities, it is recommended that dobutamine hydrochloride not be mixed with other drugs in the same solution. Dobutamine hydrochloride should not be used in conjunction with other agents or diluents containing both sodium bisulfite and ethanol.
| |
| | |
| ===Preparation and Stability===
| |
| At the time of administration, '''dobutamine injection must be further diluted in an IV container'''. Dilute 20 mL of dobutamine in at least 50 mL of diluent and dilute 40 mL of dobutamine in at least 100 mL of diluent. Use one of the following intravenous solutions as a diluent: Dextrose Injection 5%, Dextrose 5% and Sodium Chloride 0.45% Injection, Dextrose 5% and Sodium Chloride 0.9% Injection, Dextrose Injection 10%, Isolyte® M with 5% Dextrose Injection, Lactated Ringer’s Injection, 5% Dextrose in Lactated Ringer’s Injection, Normosol®-M in D5-W, 20% Osmitrol® in Water for Injection, Sodium Chloride Injection 0.9%, or Sodium Lactate Injection. '''Intravenous solutions should be used within 24 hours.'''
| |
| | |
| ===Recommended Dosage===
| |
| The rate of infusion needed to increase cardiac output usually ranged from 2.5 to 15 mcg/kg/min (see table). On rare occasions, infusion rates up to 40 mcg/kg/min have been required to obtain the desired effect.<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = DOBUTAMINE (DOBUTAMINE HYDROCHLORIDE) INJECTION, SOLUTION [HOSPIRA, INC.] | url =http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=cb842dc2-fb15-48f9-e4b1-ea4280db0199 | publisher = | date = | accessdate = }}</ref>
| |
| | |
| ==References==
| |
| {{Reflist}}
| |
| | |
| {{FDA}}
| |
| | |
| [[Category:Drugs]] | |