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__NOTOC__
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==Mixing alcohol with medicines==
==Overview==


{| style="border: 2px solid #696969;" align="center"
The most common medications reported to interact with alcohol are [[antibiotic]]s, [[antidepressant]]s, [[antihistamine]]s, [[barbiturate]]s, [[benzodiazepine]]s, [[H2 blocker]]s, [[muscle relaxant]]s, [[opioid]]s, and [[warfarin]]. Alcohol may affect [[pharmacodynamics]] and/or [[pharmacokinetics]] of medications and result in altered therapeutic effects as well as adverse reactions.
|+ <SMALL>'''''Commonly Used Medicines (Both Prescription and Over-The-Counter) That Interact With Alcohol<ref name="pubs.niaaa.nih.gov">{{Cite web  | last =  | first =  | title = http://pubs.niaaa.nih.gov/publications/Medicine/medicine.htm | url = http://pubs.niaaa.nih.gov/publications/Medicine/medicine.htm | publisher =  | date =  | accessdate = }}</ref>'''''</SMALL>
| style="background: #A5B2D6; border: 0px solid #696969; padding: 0 5px; width: 200px"| '''Symptom/Disorders'''
| style="background: #A5B2D6; border: 0px solid #696969; padding: 0 5px; width: 200px" | '''Medication (Trade Name)'''
| style="background: #A5B2D6; border: 0px solid #696969; padding: 0 5px; width: 200px" | '''Medication (Generic Name)'''


| style="background: #A5B2D6; border: 0px solid #696969; padding: 0 5px; width: 200px" | '''Possible Reactions With Alcohol'''
==Commonly Used Medicines (Both Prescription and Over-The-Counter) That Interact With Alcohol==


{| style="border: 2px solid #696969; width:880px; cellpadding: 5px 5px;" align="center"
|+ <SMALL>'''''Commonly Used Medicines (Both Prescription and Over-The-Counter) That Interact With Alcohol<ref name="pubs.niaaa.nih.gov">{{Cite web  | last =  | first =  | title = http://pubs.niaaa.nih.gov/publications/Medicine/medicine.htm | url = http://pubs.niaaa.nih.gov/publications/Medicine/medicine.htm | publisher =  | date =  | accessdate = }}</ref>'''''</SMALL>
! style="background: #A5B2D6; border: 0px solid #696969; padding: 0 5px; width:180px;"|'''Symptom/Disorders'''
! style="background: #A5B2D6; border: 0px solid #696969; padding: 0 5px; width:220px;"|'''Medication <BR> (Trade Name)'''
! style="background: #A5B2D6; border: 0px solid #696969; padding: 0 5px; width:220px;"|'''Medication <BR>  (Generic Name)'''
! style="background: #A5B2D6; border: 0px solid #696969; padding: 0 5px; width:260px;"|'''Possible Reactions With Alcohol'''
|-style="background: #EFEFEF; padding: 3px 3px;"
| rowspan=11 valign=top | Allergies/Colds/Flu||Alavert<sup>®</sup>||[[Loratadine]] || rowspan=11 valign=top | Drowsiness, dizziness; increased risk for overdose
|-style="background: #EFEFEF;"
| Allegra<sup>®</sup>, Allegra-D<sup>®</sup>||[[Fexofenadine]]
|-style="background: #EFEFEF;"
| Benadryl<sup>®</sup>||[[Diphenhydramine]]
|-style="background: #EFEFEF;"
| Clarinex<sup>®</sup>||[[Desloratadine]]
|-style="background: #EFEFEF;"
| Claritin<sup>®</sup>, Claritin-D<sup>®</sup>||[[Loratadine]]
|-style="background: #EFEFEF;"
| Dimetapp<sup>®</sup> Cold & Allergy||[[Brompheniramine]]
|-style="background: #EFEFEF;"
| Sudafed<sup>®</sup> Sinus & Allergy||[[Chlorpheniramine]]
|-style="background: #EFEFEF;"
| Triaminic<sup>®</sup> Cold & Allergy||[[Chlorpheniramine]]
|-style="background: #EFEFEF;"
| Tylenol<sup>®</sup> Allergy Sinus||[[Chlorpheniramine]]
|-style="background: #EFEFEF;"
| Tylenol<sup>®</sup> Cold & Flu||[[Chlorpheniramine]]
|-style="background: #EFEFEF;"
| Zyrtec<sup>®</sup>||[[Cetirizine]]
|-style="background: #EFEFEF;"
|rowspan=2 valign="top"| Angina (chest pain), <BR> coronary heart disease || rowspan=2 valign="top"|  Isordil<sup>®</sup> ||  [[Isosorbide]] || rowspan=2 valign="top" | Rapid heartbeat, sudden changes in blood pressure, dizziness, fainting
|-style="background: #EFEFEF;"
| [[Nitroglycerin]]
|-style="background: #EFEFEF;"
|  rowspan=7 valign=top | Anxiety and epilepsy || Ativan<sup>®</sup> || [[Lorazepam]] || rowspan=6 valign="top" | Drowsiness, dizziness; increased risk for overdose; slowed or difficulty breathing; impaired motor control; unusual behavior; and memory problems
|-style="background: #EFEFEF;"
|  Klonopin<sup>®</sup> || [[Clonazepam]]
|-style="background: #EFEFEF;"
|  Librium<sup>®</sup> || [[Chlordiazepoxide]]
|-style="background: #EFEFEF;"
|  Paxil<sup>®</sup> || [[Paroxetine]]
|-style="background: #EFEFEF;"
| Valium<sup>®</sup> || [[Diazepam]]
|-style="background: #EFEFEF;"
|  Xanax<sup>®</sup> || [[Alprazolam]]
|-style="background: #EFEFEF;"
| Herbal preparations (Kava Kava) || — || Liver damage, drowsiness
|-style="background: #EFEFEF;"
| rowspan=3 valign="top" | Arthritis || Celebrex<sup>®</sup> || [[Celecoxib]] || rowspan=3 valign="top" | Ulcers, stomach bleeding, liver problems
|-style="background: #EFEFEF;"
| Naprosyn<sup>®</sup> || [[Naproxen]]
|-style="background: #EFEFEF;"
| Voltaren<sup>®</sup> || [[Diclofenac]]
|-style="background: #EFEFEF;"
| valign="top" | Blood clots || valign="top" | Coumadin<sup>®</sup> || valign="top" | [[Warfarin]] || Occasional drinking may lead to internal bleeding; heavier drinking also may cause bleeding or may have the opposite effect, resulting in possible blood clots, strokes, or heart attacks
|-style="background: #EFEFEF;"
| rowspan="2" valign="top" | Cough || Delsym<sup>®</sup>, Robitussin Cough<sup>®</sup> || [[Dextromethorphan]] || rowspan="2" valign="top" | Drowsiness, dizziness; increased risk for overdose
|-style="background: #EFEFEF;"
| Robitussin A–C<sup>®</sup> || [[Guaifenesin]] + [[Codeine]]
|-style="background: #EFEFEF;"
| rowspan="14" valign="top" | Depression || Anafranil<sup>®</sup> || [[Clomipramine]] || rowspan="14" valign="top" | Drowsiness, dizziness; increased risk for overdose; increased feelings of depression or hopelessness in adolescents (suicide)
|-style="background: #EFEFEF;"
| Celexa<sup>®</sup> || [[Citalopram]]
|-style="background: #EFEFEF;"
| Desyrel<sup>®</sup> || [[Trazodone]]
|-style="background: #EFEFEF;"
| Effexor<sup>®</sup> || [[Venlafaxine]]
|-style="background: #EFEFEF;"
| Elavil<sup>®</sup> || [[Amitriptyline]]
|-style="background: #EFEFEF;"
| Lexapro<sup>®</sup> || [[Escitalopram]]
|-style="background: #EFEFEF;"
| Luvox<sup>®</sup> || [[Fluvoxamine]]
|-style="background: #EFEFEF;"
| Norpramin<sup>®</sup> || [[Desipramine]]
|-style="background: #EFEFEF;"
| Paxil<sup>®</sup> || [[Paroxetine]]
|-style="background: #EFEFEF;"
| Prozac<sup>®</sup> || [[Fluoxetine]]
|-style="background: #EFEFEF;"
| Serzone<sup>®</sup> || [[Nefazodone]]
|-style="background: #EFEFEF;"
| Wellbutrin<sup>®</sup> || [[Bupropion]]
|-style="background: #EFEFEF;"
| Zoloft<sup>®</sup> || [[Sertraline]]
|-style="background: #EFEFEF;"
| St. John’s Wort || —
|-style="background: #EFEFEF;"
| rowspan=3 valign="top" | Diabetes || Glucophage<sup>®</sup> || [[Metformin]] || rowspan=3 valign="top" | Abnormally low blood sugar levels, flushing reaction (nausea, vomiting, headache, rapid heartbeat, sudden changes in blood pressure)
|-style="background: #EFEFEF;"
| Micronase<sup>®</sup> || [[Glyburide]]
|-style="background: #EFEFEF;"
| valign="top" | Orinase<sup>®</sup> || valign="top" | [[Tolbutamide]]
|-style="background: #EFEFEF;"
| rowspan=4 valign="top" | Enlarged prostate|| Cardura<sup>®</sup> || [[Doxazosin]] || rowspan=4 valign="top" | Dizziness, light headedness, fainting
|-style="background: #EFEFEF;"
| Flomax<sup>®</sup> || [[Tamsulosin]]
|-style="background: #EFEFEF;"
| Hytrin<sup>®</sup> || [[Terazosin]]
|-style="background: #EFEFEF;"
| Minipress<sup>®</sup> || [[Prazosin]]
|-style="background: #EFEFEF;"
| rowspan=4 valign="top" | Heartburn, indigestion, <BR> sour stomach || Axid<sup>®</sup> || [[Nizatidine]] || rowspan=4 valign="top" | Rapid heartbeat, sudden changes in blood pressure (metoclopramide); increased alcohol effect
|-style="background: #EFEFEF;"
| Reglan<sup>®</sup> || [[Metoclopramide]]
|-style="background: #EFEFEF;"
| Tagamet<sup>®</sup> || [[Cimetidine]]
|-style="background: #EFEFEF;"
| Zantac<sup>®</sup> || [[Ranitidine]]
|-style="background: #EFEFEF;"
| rowspan=10 valign="top" | High blood pressure || Accupril<sup>®</sup> || [[Quinapril]] || rowspan=10 valign="top" | Dizziness, fainting, drowsiness; heart problems such as changes in the heart’s regular heartbeat (arrhythmia)
|-style="background: #EFEFEF;"
| Capozide<sup>®</sup> || [[Hydrochlorothiazide]]
|-style="background: #EFEFEF;"
| Cardura<sup>®</sup> || [[Doxazosin]]
|-style="background: #EFEFEF;"
| Catapres<sup>®</sup> || [[Clonidine]]
|-style="background: #EFEFEF;"
| Cozaar<sup>®</sup> || [[Losartan]]
|-style="background: #EFEFEF;"
| Hytrin<sup>®</sup> || [[Terazosin]]
|-style="background: #EFEFEF;"
| Lopressor<sup>®</sup> HCT || [[Hydrochlorothiazide]]
|-style="background: #EFEFEF;"
| Lotensin<sup>®</sup> || [[Benzapril]]
|-style="background: #EFEFEF;"
| Minipress<sup>®</sup> || [[Prazosin]]
|-style="background: #EFEFEF;"
| Vaseretic<sup>®</sup> || [[Enalapril]]
|-style="background: #EFEFEF;"
| rowspan=10 valign="top" | High cholesterol|| Advicor<sup>®</sup> || [[Lovastatin]] + [[Niacin]] || rowspan=10 valign="top" | Liver damage (all medications); increased flushing and itching (niacin), increased stomach bleeding (pravastatin + aspirin)
|-style="background: #EFEFEF;"
| Altocor<sup>®</sup> || [[Lovastatin]]
|-style="background: #EFEFEF;"
| Crestor<sup>®</sup> || [[Rosuvastatin]]
|-style="background: #EFEFEF;"
| Lipitor<sup>®</sup> || [[Atorvastatin]]
|-style="background: #EFEFEF;"
| Mevacor<sup>®</sup> || [[Lovastatin]]
|-style="background: #EFEFEF;"
| Niaspan<sup>®</sup> || [[Niacin]]
|-style="background: #EFEFEF;"
| Pravachol<sup>®</sup> || [[Pravastatin]]
|-style="background: #EFEFEF;"
| Pravigard<sup>®</sup> || [[Pravastatin]] + [[Aspirin]]
|-style="background: #EFEFEF;"
| Vytorin<sup>®</sup> || [[Ezetimibe]] + [[Simvastatin]]
|-style="background: #EFEFEF;"
| Zocor<sup>®</sup> || [[Simvastatin]]
|-style="background: #EFEFEF;"
| rowspan=7 valign="top" | Infections || Acrodantin<sup>®</sup> || [[Nitrofurantoin]] || rowspan=7 valign="top" | Fast heartbeat, sudden changes in blood pressure; stomach pain, upset stomach, vomiting, headache, or flushing or redness of the face; liver damage (isoniazid, ketoconazole)
|-style="background: #EFEFEF;"
| Flagyl<sup>®</sup> || [[Metronidazole]]
|-style="background: #EFEFEF;"
| Grisactin<sup>®</sup> || [[Griseofulvin]]
|-style="background: #EFEFEF;"
| Nizoral<sup>®</sup> || [[Ketoconazole]]
|-style="background: #EFEFEF;"
| Nydrazid<sup>®</sup> || [[Isoniazid]]
|-style="background: #EFEFEF;"
| Seromycin<sup>®</sup> || [[Cycloserine]]
|-style="background: #EFEFEF;"
| Tindamax<sup>®</sup> || [[Tinidazole]]
|-style="background: #EFEFEF;"
| rowspan=2 valign="top" | Muscle pain || Flexeril<sup>®</sup> || [[Cyclobenzaprine]] || rowspan=2 valign="top" | Drowsiness, dizziness; increased risk of seizures; increased risk for overdose; slowed or difficulty breathing; impaired motor control; unusual behavior; memory problems
|-style="background: #EFEFEF;"
| valign="top" | Soma<sup>®</sup> || valign="top" | [[Carisoprodol]]
|-style="background: #EFEFEF;"
| rowspan=4 valign="top" | Nausea, motion sickness || Antivert<sup>®</sup> || [[Meclizine]] || rowspan=4 valign="top" | Drowsiness, dizziness; increased risk for overdose
|-style="background: #EFEFEF;"
| Atarax<sup>®</sup> || [[Hydroxyzine]]
|-style="background: #EFEFEF;"
| Dramamine<sup>®</sup> || [[Dimenhydrinate]]
|-style="background: #EFEFEF;"
| Phenergan<sup>®</sup> || [[Promethazine]]
|-style="background: #EFEFEF;"
| rowspan=5 valign="top" | Pain (such as headache, muscle ache, minor arthritis pain), fever, inflammation || Advil<sup>®</sup> || [[Ibuprofen]] || rowspan=5 valign="top" | Stomach upset, bleeding and ulcers; liver damage (acetaminophen); rapid heartbeat
|-style="background: #EFEFEF;"
| Aleve<sup>®</sup> || [[Naproxen]]
|-style="background: #EFEFEF;"
| Excedrin<sup>®</sup> || [[Aspirin]], [[Acetaminophen]]
|-style="background: #EFEFEF;"
| Motrin<sup>®</sup> || [[Ibuprofen]]
|-style="background: #EFEFEF;"
| Tylenol<sup>®</sup> || [[Acetaminophen]]
|-style="background: #EFEFEF;"
| rowspan=3 valign="top" | Seizures|| Dilantin<sup>®</sup> || [[Phenytoin]] || rowspan=3 valign="top" | Drowsiness, dizziness; increased risk of seizures
|-style="background: #EFEFEF;"
| Klonopin<sup>®</sup> || [[Clonazepam]]
, [[Phenobarbital]]
|-style="background: #EFEFEF;"
| Phenobarbital || [[Phenobarbital]]
|-style="background: #EFEFEF;"
| rowspan=5 valign="top" | Severe pain from injury, postsurgical care, oral <BR> surgery, migraines|| Darvocet–N<sup>®</sup> || [[Propoxyphene]] || rowspan=5 valign="top" | Drowsiness, dizziness; increased risk for overdose; slowed or difficulty breathing; impaired motor control; unusual behavior; memory problems
|-style="background: #EFEFEF;"
| Demerol<sup>®</sup> || [[Meperidine]]
|-style="background: #EFEFEF;"
| Fiorinal<sup>®</sup> with codeine || [[Butalbital]] + [[Codeine]]
|-style="background: #EFEFEF;"
| Percocet<sup>®</sup> || [[Oxycodone]]
|-style="background: #EFEFEF;"
| Vicodin<sup>®</sup> || [[Hydrocodone]]
|-style="background: #EFEFEF;"
| rowspan=7 valign="top" | Sleep problems || Ambien<sup>®</sup> || [[Zolpidem]] || rowspan=6 valign="top" | Drowsiness, sleepiness, dizziness; slowed or difficulty breathing; impaired motor control; unusual behavior; memory problems
|-style="background: #EFEFEF;"
| Lunesta<sup>®</sup> || [[Eszopiclone]]
|-style="background: #EFEFEF;"
| Prosom<sup>®</sup> || [[Estazolam]]
|-style="background: #EFEFEF;"
| Restoril<sup>®</sup> || [[Temazepam]]
|-style="background: #EFEFEF;"
| Sominex<sup>®</sup> || [[Diphenhydramine]]
|-style="background: #EFEFEF;"
| Unisom<sup>®</sup> || [[Doxylamine]]
|-style="background: #EFEFEF;"
| Herbal preparations <BR> (chamomile, valerian, lavender) || valign="top" | — || valign="top" | Increased drowsiness
|-
|-
| Allergies/Colds/Flu || Alavert® || Loratadine || Drowsiness, dizziness; increased risk for overdose
|-
|;&nbsp|| Allegra®, Allegra-D®||Fexofenadin|| 3213
|-
| || Benadryl®||Diphenhydramine||
|-
| || Clarinex®||Desloratadine||
|-
| || Claritin®, Claritin-D®||Loratadine||
|-
| || Dimetapp® Cold & Allergy||Brompheniramine||
|-
| || Sudafed® Sinus & Allergy||Chlorpheniramine||
|-
| || Triaminic® Cold & Allergy||Chlorpheniramine||
|-
| || Tylenol® Allergy Sinus||Chlorpheniramine||
|-
| || Tylenol® Cold & Flu||Chlorpheniramine||
|-
| || Zyrtec®||Cetirizine||
|-
| Angina (chest pain), coronary heart disease|| Isordil®||Isosorbide||Rapid heartbeat, sudden changes in blood pressure, dizziness, fainting
|-
| ||||Nitroglycerin||
|-
| Anxiety and epilepsy|| Ativan®||Lorazepam||Drowsiness, dizziness; increased risk for overdose; slowed or difficulty breathing; impaired motor control; unusual behavior; and memory problems
|-
| || Klonopin®||Clonazepam||
|-
| || Librium®||Chlordiazepoxide||
|-
| || Paxil®||Paroxetine||
|-
| || Valium®||Diazepam||
|-
| || Xanax®||Alprazolam||
|-
| || Herbal preparations (Kava Kava)|| ||Liver damage, drowsiness
|-
| Arthritis|| Celebrex®||Celecoxib||Ulcers, stomach bleeding, liver problems
|-
| || Naprosyn®||Naproxen||
|-
| || Voltaren®||Diclofenac||
|-
| Blood clots|| Coumadin®||Warfarin||Occasional drinking may lead to internal bleeding; heavier drinking also may cause bleeding or may have the opposite effect, resulting in possible blood clots, strokes, or heart attacks
|-
| Cough|| Delsym®, Robitussin Cough®||Dextromethorpan||Drowsiness, dizziness; increased risk for overdose
|-
| || Robitussin A–C®||Guaifenesin + codeine||
|-
| Depression|| Anafranil®||Clomipramine||Drowsiness, dizziness; increased risk for overdose; increased feelings of depression or hopelessness in adolescents (suicide)
|-
| || Celexa®||Citalopram||
|-
| || Desyrel®||Trazodone||
|-
| || Effexor®||Venlafaxine||
|-
| || Elavil®||Amitriptyline||
|-
| || Lexapro®||Escitalopram||
|-
| || Luvox®||Fluvoxamine||
|-
| || Norpramin®||Desipramine||
|-
| || Paxil®||Paroxetine||
|-
| || Prozac®||Fluoxetine||
|-
| || Serzone®||Nefazodone||
|-
| || Wellbutrin®||Bupropion||
|-
| || Zoloft®||Sertraline||
|-
| || Herbal preparations (St. John’s Wort)|| ||
|-
| Diabetes|| Glucophage®||Metformin||Abnormally low blood sugar levels, flushing reaction (nausea, vomiting, headache, rapid heartbeat, sudden changes in blood pressure)
|-
| || Micronase®||Glyburide||
|-
| || Orinase®||Tolbutamide||
|-
| Enlarged prostate|| Cardura®||Doxazosin||Dizziness, light headedness, fainting
|-
| || Flomax®||Tamsulosin||
|-
| || Hytrin®||Terazosin||
|-
| || Minipress®||Prazosin||
|-
| Heartburn, indigestion, sour stomach|| Axid®||Nizatidine||Rapid heartbeat, sudden changes in blood pressure (metoclopramide); increased alcohol effect
|-
| || Reglan®||Metoclopramide||
|-
| || Tagamet®||Cimetidine||
|-
| || Zantac®||Ranitidine||
|-
| High blood pressure|| Accupril®||Quinapril||Dizziness, fainting, drowsiness; heart problems such as changes in the heart’s regular heartbeat (arrhythmia)
|-
| || Capozide®||Hydrochlorothiazide||
|-
| || Cardura®||Doxazosin||
|-
| || Catapres®||Clonidine||
|-
| || Cozaar®||Losartan||
|-
| || Hytrin®||Terazosin||
|-
| || Lopressor® HCT||Hydrochlorothiazide||
|-
| || Lotensin®||Benzapril||
|-
| || Minipress®||Prazosin||
|-
| || Vaseretic®||Enalapril||
|-
| High cholesterol|| Advicor®||Lovastatin + Niacin||Liver damage (all medications); increased flushing and itching (niacin), increased stomach bleeding (pravastatin + aspirin)
|-
| || Altocor®||Lovastatin||
|-
| || Crestor®||Rosuvastatin||
|-
| || Lipitor®||Atorvastatin||
|-
| || Mevacor®||Lovastatin||
|-
| || Niaspan®||Niacin||
|-
| || Pravachol®||Pravastatin||
|-
| || Pravigard™||Pravastatin + Aspirin||
|-
| || Vytorin™||Ezetimibe + Simvastatin||
|-
| || Zocor®||Simvastatin||
|-
| Infections|| Acrodantin®||Nitrofurantoin||Fast heartbeat, sudden changes in blood pressure; stomach pain, upset stomach, vomiting, headache, or flushing or redness of the face; liver damage (isoniazid, ketokonazole)
|-
| || Flagyl®||Metronidazole||
|-
| || Grisactin®||Griseofulvin||
|-
| || Nizoral®||Ketokonazole||
|-
| || Nydrazid®||Isoniazid||
|-
| || Seromycin®||Cycloserine||
|-
| || Tindamax®||Tinidazole||
|-
| Muscle pain|| Flexeril®||Cyclobenzaprine||Drowsiness, dizziness; increased risk of seizures; increased risk for overdose; slowed or difficulty breathing; impaired motor control; unusual behavior; memory problems
|-
| || Soma®||Carisoprodol||
|-
| Nausea, motion sickness|| Antivert®||Meclizine||Drowsiness, dizziness; increased risk for overdose
|-
| || Atarax®||Hydroxyzine||
|-
| || Dramamine®||Dimenhydrinate||
|-
| || Phenergan®||Promethazine||
|-
| Pain (such as headache, muscle ache, minor arthritis pain), fever, inflammation|| Advil®||Ibuprofen||Stomach upset, bleeding and ulcers; liver damage (acetaminophen); rapid heartbeat
|-
| || Aleve®||Naproxen||
|-
| || Excedrin®||Aspirin, Acetaminophen||
|-
| || Motrin®||Ibuprofen||
|-
| || Tylenol®||Acetaminophen||
|-
| Seizures|| Dilantin®||Phenytoin||Drowsiness, dizziness; increased risk of seizures
|-
| || Klonopin®||Clonazepam
Phenobarbital||
|-
| Severe pain from injury, postsurgical care, oral surgery, migraines|| Darvocet–N®||Propoxyphene||Drowsiness, dizziness; increased risk for overdose; slowed or difficulty breathing; impaired motor control; unusual behavior; memory problems
|-
| || Demerol®||Merepidine||
|-
| || Fiorinal® with codeine||Butalbital + codeine||
|-
| || Percocet®||Oxycodone||
|-
| || Vicodin®||Hydrocodone||
|-
| Sleep problems|| Ambien®||Zolpidem||Drowsiness, sleepiness, dizziness; slowed or difficulty breathing; impaired motor control; unusual behavior; memory problems
|-
| || Lunesta™||Eszopiclone||
|-
| || Prosom™||Estazolam||
|-
| || Restoril®||Temazepam||
|-
| || Sominex®||Diphenhydramine||
|-
| || Unisom®||Doxylamine||
|-
| || Herbal preparations (chamomile, valerian, lavender)|| ||Increased drowsiness
|-
|
|}
|}


Latest revision as of 17:19, 20 February 2014

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

The most common medications reported to interact with alcohol are antibiotics, antidepressants, antihistamines, barbiturates, benzodiazepines, H2 blockers, muscle relaxants, opioids, and warfarin. Alcohol may affect pharmacodynamics and/or pharmacokinetics of medications and result in altered therapeutic effects as well as adverse reactions.

Commonly Used Medicines (Both Prescription and Over-The-Counter) That Interact With Alcohol

Commonly Used Medicines (Both Prescription and Over-The-Counter) That Interact With Alcohol[1]
Symptom/Disorders Medication
(Trade Name) 		Medication
(Generic Name) 		Possible Reactions With Alcohol
Allergies/Colds/Flu Alavert® Loratadine Drowsiness, dizziness; increased risk for overdose
Allegra®, Allegra-D® Fexofenadine
Benadryl® Diphenhydramine
Clarinex® Desloratadine
Claritin®, Claritin-D® Loratadine
Dimetapp® Cold & Allergy Brompheniramine
Sudafed® Sinus & Allergy Chlorpheniramine
Triaminic® Cold & Allergy Chlorpheniramine
Tylenol® Allergy Sinus Chlorpheniramine
Tylenol® Cold & Flu Chlorpheniramine
Zyrtec® Cetirizine
Angina (chest pain),
coronary heart disease		 Isordil® Isosorbide Rapid heartbeat, sudden changes in blood pressure, dizziness, fainting
Nitroglycerin
Anxiety and epilepsy Ativan® Lorazepam Drowsiness, dizziness; increased risk for overdose; slowed or difficulty breathing; impaired motor control; unusual behavior; and memory problems
Klonopin® Clonazepam
Librium® Chlordiazepoxide
Paxil® Paroxetine
Valium® Diazepam
Xanax® Alprazolam
Herbal preparations (Kava Kava) — Liver damage, drowsiness
Arthritis Celebrex® Celecoxib Ulcers, stomach bleeding, liver problems
Naprosyn® Naproxen
Voltaren® Diclofenac
Blood clots Coumadin® Warfarin Occasional drinking may lead to internal bleeding; heavier drinking also may cause bleeding or may have the opposite effect, resulting in possible blood clots, strokes, or heart attacks
Cough Delsym®, Robitussin Cough® Dextromethorphan Drowsiness, dizziness; increased risk for overdose
Robitussin A–C® Guaifenesin + Codeine
Depression Anafranil® Clomipramine Drowsiness, dizziness; increased risk for overdose; increased feelings of depression or hopelessness in adolescents (suicide)
Celexa® Citalopram
Desyrel® Trazodone
Effexor® Venlafaxine
Elavil® Amitriptyline
Lexapro® Escitalopram
Luvox® Fluvoxamine
Norpramin® Desipramine
Paxil® Paroxetine
Prozac® Fluoxetine
Serzone® Nefazodone
Wellbutrin® Bupropion
Zoloft® Sertraline
St. John’s Wort —
Diabetes Glucophage® Metformin Abnormally low blood sugar levels, flushing reaction (nausea, vomiting, headache, rapid heartbeat, sudden changes in blood pressure)
Micronase® Glyburide
Orinase® Tolbutamide
Enlarged prostate Cardura® Doxazosin Dizziness, light headedness, fainting
Flomax® Tamsulosin
Hytrin® Terazosin
Minipress® Prazosin
Heartburn, indigestion,
sour stomach		 Axid® Nizatidine Rapid heartbeat, sudden changes in blood pressure (metoclopramide); increased alcohol effect
Reglan® Metoclopramide
Tagamet® Cimetidine
Zantac® Ranitidine
High blood pressure Accupril® Quinapril Dizziness, fainting, drowsiness; heart problems such as changes in the heart’s regular heartbeat (arrhythmia)
Capozide® Hydrochlorothiazide
Cardura® Doxazosin
Catapres® Clonidine
Cozaar® Losartan
Hytrin® Terazosin
Lopressor® HCT Hydrochlorothiazide
Lotensin® Benzapril
Minipress® Prazosin
Vaseretic® Enalapril
High cholesterol Advicor® Lovastatin + Niacin Liver damage (all medications); increased flushing and itching (niacin), increased stomach bleeding (pravastatin + aspirin)
Altocor® Lovastatin
Crestor® Rosuvastatin
Lipitor® Atorvastatin
Mevacor® Lovastatin
Niaspan® Niacin
Pravachol® Pravastatin
Pravigard® Pravastatin + Aspirin
Vytorin® Ezetimibe + Simvastatin
Zocor® Simvastatin
Infections Acrodantin® Nitrofurantoin Fast heartbeat, sudden changes in blood pressure; stomach pain, upset stomach, vomiting, headache, or flushing or redness of the face; liver damage (isoniazid, ketoconazole)
Flagyl® Metronidazole
Grisactin® Griseofulvin
Nizoral® Ketoconazole
Nydrazid® Isoniazid
Seromycin® Cycloserine
Tindamax® Tinidazole
Muscle pain Flexeril® Cyclobenzaprine Drowsiness, dizziness; increased risk of seizures; increased risk for overdose; slowed or difficulty breathing; impaired motor control; unusual behavior; memory problems
Soma® Carisoprodol
Nausea, motion sickness Antivert® Meclizine Drowsiness, dizziness; increased risk for overdose
Atarax® Hydroxyzine
Dramamine® Dimenhydrinate
Phenergan® Promethazine
Pain (such as headache, muscle ache, minor arthritis pain), fever, inflammation Advil® Ibuprofen Stomach upset, bleeding and ulcers; liver damage (acetaminophen); rapid heartbeat
Aleve® Naproxen
Excedrin® Aspirin, Acetaminophen
Motrin® Ibuprofen
Tylenol® Acetaminophen
Seizures Dilantin® Phenytoin Drowsiness, dizziness; increased risk of seizures
Klonopin® Clonazepam
, Phenobarbital
Phenobarbital Phenobarbital
Severe pain from injury, postsurgical care, oral
surgery, migraines		 Darvocet–N® Propoxyphene Drowsiness, dizziness; increased risk for overdose; slowed or difficulty breathing; impaired motor control; unusual behavior; memory problems
Demerol® Meperidine
Fiorinal® with codeine Butalbital + Codeine
Percocet® Oxycodone
Vicodin® Hydrocodone
Sleep problems Ambien® Zolpidem Drowsiness, sleepiness, dizziness; slowed or difficulty breathing; impaired motor control; unusual behavior; memory problems
Lunesta® Eszopiclone
Prosom® Estazolam
Restoril® Temazepam
Sominex® Diphenhydramine
Unisom® Doxylamine
Herbal preparations
(chamomile, valerian, lavender)		 — Increased drowsiness

References

  1. ↑ "http://pubs.niaaa.nih.gov/publications/Medicine/medicine.htm". External link in |title= (help)
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