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==Mixing alcohol with medicines==
==Overview==


{| style="border: 2px solid #696969; width:800px;" align="center"
The most common medications reported to interact with alcohol are [[antibiotic]]s, [[antidepressant]]s, [[antihistamine]]s, [[barbiturate]]s, [[benzodiazepine]]s, [[H2 blocker]]s, [[muscle relaxant]]s, [[opioid]]s, and [[warfarin]]. Alcohol may affect [[pharmacodynamics]] and/or [[pharmacokinetics]] of medications and result in altered therapeutic effects as well as adverse reactions.
 
==Commonly Used Medicines (Both Prescription and Over-The-Counter) That Interact With Alcohol==
 
{| style="border: 2px solid #696969; width:880px; cellpadding: 5px 5px;" align="center"
|+ <SMALL>'''''Commonly Used Medicines (Both Prescription and Over-The-Counter) That Interact With Alcohol<ref name="pubs.niaaa.nih.gov">{{Cite web  | last =  | first =  | title = http://pubs.niaaa.nih.gov/publications/Medicine/medicine.htm | url = http://pubs.niaaa.nih.gov/publications/Medicine/medicine.htm | publisher =  | date =  | accessdate = }}</ref>'''''</SMALL>
|+ <SMALL>'''''Commonly Used Medicines (Both Prescription and Over-The-Counter) That Interact With Alcohol<ref name="pubs.niaaa.nih.gov">{{Cite web  | last =  | first =  | title = http://pubs.niaaa.nih.gov/publications/Medicine/medicine.htm | url = http://pubs.niaaa.nih.gov/publications/Medicine/medicine.htm | publisher =  | date =  | accessdate = }}</ref>'''''</SMALL>
! style="background: #A5B2D6; border: 0px solid #696969; padding: 0 5px; width:180px;"|'''Symptom/Disorders'''
! style="background: #A5B2D6; border: 0px solid #696969; padding: 0 5px; width:180px;"|'''Symptom/Disorders'''
! style="background: #A5B2D6; border: 0px solid #696969; padding: 0 5px; width:180px;"|'''Medication <BR> (Trade Name)'''
! style="background: #A5B2D6; border: 0px solid #696969; padding: 0 5px; width:220px;"|'''Medication <BR> (Trade Name)'''
! style="background: #A5B2D6; border: 0px solid #696969; padding: 0 5px; width:180px;"|'''Medication <BR>  (Generic Name)'''
! style="background: #A5B2D6; border: 0px solid #696969; padding: 0 5px; width:220px;"|'''Medication <BR>  (Generic Name)'''
! style="background: #A5B2D6; border: 0px solid #696969; padding: 0 5px; width:260px;"|'''Possible Reactions With Alcohol'''
! style="background: #A5B2D6; border: 0px solid #696969; padding: 0 5px; width:260px;"|'''Possible Reactions With Alcohol'''
|-style="background: #EFEFEF; padding: 3px 3px;"
| rowspan=11 valign=top | Allergies/Colds/Flu||Alavert<sup>®</sup>||[[Loratadine]] || rowspan=11 valign=top | Drowsiness, dizziness; increased risk for overdose
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| rowspan=11 valign=top | Allergies/Colds/Flu||Alavert®||[[Loratadine]]|| rowspan=11 valign=top | Drowsiness, dizziness; increased risk for overdose
| Allegra<sup>®</sup>, Allegra-D<sup>®</sup>||[[Fexofenadine]]
|-style="background: #EFEFEF;"
| Allegra®, Allegra-D®||[[Fexofenadine]]||
|-style="background: #EFEFEF;"
| Benadryl®||[[Diphenhydramine]]||
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| Clarinex®||[[Desloratadine]]||
| Benadryl<sup>®</sup>||[[Diphenhydramine]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| Claritin®, Claritin-D®||[[Loratadine]]||
| Clarinex<sup>®</sup>||[[Desloratadine]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| Dimetapp® Cold & Allergy||[[Brompheniramine]]||
| Claritin<sup>®</sup>, Claritin-D<sup>®</sup>||[[Loratadine]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| Sudafed® Sinus & Allergy||[[Chlorpheniramine]]||
| Dimetapp<sup>®</sup> Cold & Allergy||[[Brompheniramine]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| Triaminic® Cold & Allergy||[[Chlorpheniramine]]||
| Sudafed<sup>®</sup> Sinus & Allergy||[[Chlorpheniramine]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| Tylenol® Allergy Sinus||[[Chlorpheniramine]]||
| Triaminic<sup>®</sup> Cold & Allergy||[[Chlorpheniramine]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| Tylenol® Cold & Flu||[[Chlorpheniramine]]||
| Tylenol<sup>®</sup> Allergy Sinus||[[Chlorpheniramine]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| Zyrtec®||[[Cetirizine]]||
| Tylenol<sup>®</sup> Cold & Flu||[[Chlorpheniramine]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| Angina (chest pain), coronary heart disease || Isordil® ||  [[Isosorbide]] || rowspan=2 valign="top" | Rapid heartbeat, sudden changes in blood pressure, dizziness, fainting
| Zyrtec<sup>®</sup>||[[Cetirizine]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || || [[Nitroglycerin]] ||
|rowspan=2 valign="top"| Angina (chest pain), <BR> coronary heart disease || rowspan=2 valign="top"| Isordil<sup>®</sup> ||  [[Isosorbide]] || rowspan=2 valign="top" | Rapid heartbeat, sudden changes in blood pressure, dizziness, fainting
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| Anxiety and epilepsy || Ativan® || [[Lorazepam]] || rowspan=6 valign="top" | Drowsiness, dizziness; increased risk for overdose; slowed or difficulty breathing; impaired motor control; unusual behavior; and memory problems
| [[Nitroglycerin]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Klonopin® || [[Clonazepam]] ||
| rowspan=7 valign=top | Anxiety and epilepsy || Ativan<sup>®</sup> || [[Lorazepam]] || rowspan=6 valign="top" | Drowsiness, dizziness; increased risk for overdose; slowed or difficulty breathing; impaired motor control; unusual behavior; and memory problems
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Librium® || [[Chlordiazepoxide]] ||
|   Klonopin<sup>®</sup> || [[Clonazepam]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Paxil® || [[Paroxetine]] ||
|   Librium<sup>®</sup> || [[Chlordiazepoxide]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Valium® || [[Diazepam]] ||
| Paxil<sup>®</sup> || [[Paroxetine]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Xanax® || [[Alprazolam]] ||
| Valium<sup>®</sup> || [[Diazepam]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Herbal preparations (Kava Kava) || — || Liver damage, drowsiness
| Xanax<sup>®</sup> || [[Alprazolam]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| Arthritis || Celebrex® || [[Celecoxib]] || rowspan=3 valign="top" | Ulcers, stomach bleeding, liver problems
| Herbal preparations (Kava Kava) || — || Liver damage, drowsiness
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Naprosyn® || [[Naproxen]] ||
| rowspan=3 valign="top" | Arthritis || Celebrex<sup>®</sup> || [[Celecoxib]] || rowspan=3 valign="top" | Ulcers, stomach bleeding, liver problems
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Voltaren® || [[Diclofenac]] ||
| Naprosyn<sup>®</sup> || [[Naproxen]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| valign="top" | Blood clots || valign="top" | Coumadin® || valign="top" | [[Warfarin]] || valign="top" | Occasional drinking may lead to internal bleeding; heavier drinking also may cause bleeding or may have the opposite effect, resulting in possible blood clots, strokes, or heart attacks
| Voltaren<sup>®</sup> || [[Diclofenac]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| Cough || Delsym®, Robitussin Cough® || [[Dextromethorphan]] || rowspan="2" valign="top" | Drowsiness, dizziness; increased risk for overdose
| valign="top" | Blood clots || valign="top" | Coumadin<sup>®</sup> || valign="top" | [[Warfarin]] || Occasional drinking may lead to internal bleeding; heavier drinking also may cause bleeding or may have the opposite effect, resulting in possible blood clots, strokes, or heart attacks
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Robitussin A–C® || [[Guaifenesin]] + [[Codeine]] ||
| rowspan="2" valign="top" | Cough || Delsym<sup>®</sup>, Robitussin Cough<sup>®</sup> || [[Dextromethorphan]] || rowspan="2" valign="top" | Drowsiness, dizziness; increased risk for overdose
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| Depression || Anafranil® || [[Clomipramine]] || rowspan="14" valign="top" | Drowsiness, dizziness; increased risk for overdose; increased feelings of depression or hopelessness in adolescents (suicide)
| Robitussin A–C<sup>®</sup> || [[Guaifenesin]] + [[Codeine]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Celexa® || [[Citalopram]] ||
| rowspan="14" valign="top" | Depression || Anafranil<sup>®</sup> || [[Clomipramine]] || rowspan="14" valign="top" | Drowsiness, dizziness; increased risk for overdose; increased feelings of depression or hopelessness in adolescents (suicide)
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Desyrel® || [[Trazodone]] ||
| Celexa<sup>®</sup> || [[Citalopram]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Effexor® || [[Venlafaxine]] ||
| Desyrel<sup>®</sup> || [[Trazodone]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Elavil® || [[Amitriptyline]] ||
| Effexor<sup>®</sup> || [[Venlafaxine]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Lexapro® || [[Escitalopram]] ||
| Elavil<sup>®</sup> || [[Amitriptyline]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Luvox® || [[Fluvoxamine]] ||
| Lexapro<sup>®</sup> || [[Escitalopram]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Norpramin® || [[Desipramine]] ||
| Luvox<sup>®</sup> || [[Fluvoxamine]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Paxil® || [[Paroxetine]] ||
| Norpramin<sup>®</sup> || [[Desipramine]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Prozac® || [[Fluoxetine]] ||
| Paxil<sup>®</sup> || [[Paroxetine]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Serzone® || [[Nefazodone]] ||
| Prozac<sup>®</sup> || [[Fluoxetine]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Wellbutrin® || [[Bupropion]] ||
| Serzone<sup>®</sup> || [[Nefazodone]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Zoloft® || [[Sertraline]] ||
| Wellbutrin<sup>®</sup> || [[Bupropion]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Herbal preparations (St. John’s Wort) || — ||
| Zoloft<sup>®</sup> || [[Sertraline]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| Diabetes || Glucophage® || [[Metformin]] || rowspan=3 valign="top" | Abnormally low blood sugar levels, flushing reaction (nausea, vomiting, headache, rapid heartbeat, sudden changes in blood pressure)
| St. John’s Wort || —
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Micronase® || [[Glyburide]] ||
| rowspan=3 valign="top" | Diabetes || Glucophage<sup>®</sup> || [[Metformin]] || rowspan=3 valign="top" | Abnormally low blood sugar levels, flushing reaction (nausea, vomiting, headache, rapid heartbeat, sudden changes in blood pressure)
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Orinase® || [[Tolbutamide]] ||
| Micronase<sup>®</sup> || [[Glyburide]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| Enlarged prostate|| Cardura® || [[Doxazosin]] || rowspan=4 valign="top" | Dizziness, light headedness, fainting
| valign="top" | Orinase<sup>®</sup> || valign="top" | [[Tolbutamide]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Flomax® || [[Tamsulosin]] ||
| rowspan=4 valign="top" | Enlarged prostate|| Cardura<sup>®</sup> || [[Doxazosin]] || rowspan=4 valign="top" | Dizziness, light headedness, fainting
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Hytrin® || [[Terazosin]] ||
| Flomax<sup>®</sup> || [[Tamsulosin]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Minipress® || [[Prazosin]] ||
| Hytrin<sup>®</sup> || [[Terazosin]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| Heartburn, indigestion, sour stomach || Axid® || [[Nizatidine]] || rowspan=4 valign="top" | Rapid heartbeat, sudden changes in blood pressure (metoclopramide); increased alcohol effect
| Minipress<sup>®</sup> || [[Prazosin]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Reglan® || [[Metoclopramide]] ||
| rowspan=4 valign="top" | Heartburn, indigestion, <BR> sour stomach || Axid<sup>®</sup> || [[Nizatidine]] || rowspan=4 valign="top" | Rapid heartbeat, sudden changes in blood pressure (metoclopramide); increased alcohol effect
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Tagamet® || [[Cimetidine]] ||
| Reglan<sup>®</sup> || [[Metoclopramide]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Zantac® || [[Ranitidine]] ||
| Tagamet<sup>®</sup> || [[Cimetidine]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| High blood pressure || Accupril® || [[Quinapril]] || rowspan=10 valign="top" | Dizziness, fainting, drowsiness; heart problems such as changes in the heart’s regular heartbeat (arrhythmia)
| Zantac<sup>®</sup> || [[Ranitidine]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Capozide® || [[Hydrochlorothiazide]] ||
| rowspan=10 valign="top" | High blood pressure || Accupril<sup>®</sup> || [[Quinapril]] || rowspan=10 valign="top" | Dizziness, fainting, drowsiness; heart problems such as changes in the heart’s regular heartbeat (arrhythmia)
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Cardura® || [[Doxazosin]] ||
| Capozide<sup>®</sup> || [[Hydrochlorothiazide]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Catapres® || [[Clonidine]] ||
| Cardura<sup>®</sup> || [[Doxazosin]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Cozaar® || [[Losartan]] ||
| Catapres<sup>®</sup> || [[Clonidine]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Hytrin® || [[Terazosin]] ||
| Cozaar<sup>®</sup> || [[Losartan]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Lopressor® HCT || [[Hydrochlorothiazide]] ||
| Hytrin<sup>®</sup> || [[Terazosin]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Lotensin® || [[Benzapril]] ||
| Lopressor<sup>®</sup> HCT || [[Hydrochlorothiazide]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Minipress® || [[Prazosin]] ||
| Lotensin<sup>®</sup> || [[Benzapril]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Vaseretic® || [[Enalapril]] ||
| Minipress<sup>®</sup> || [[Prazosin]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| High cholesterol|| Advicor® || [[Lovastatin]] + [[Niacin]] || rowspan=10 valign="top" | Liver damage (all medications); increased flushing and itching (niacin), increased stomach bleeding (pravastatin + aspirin)
| Vaseretic<sup>®</sup> || [[Enalapril]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Altocor® || [[Lovastatin]] ||
| rowspan=10 valign="top" | High cholesterol|| Advicor<sup>®</sup> || [[Lovastatin]] + [[Niacin]] || rowspan=10 valign="top" | Liver damage (all medications); increased flushing and itching (niacin), increased stomach bleeding (pravastatin + aspirin)
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Crestor® || [[Rosuvastatin]] ||
| Altocor<sup>®</sup> || [[Lovastatin]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Lipitor® || [[Atorvastatin]] ||
| Crestor<sup>®</sup> || [[Rosuvastatin]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Mevacor® || [[Lovastatin]] ||
| Lipitor<sup>®</sup> || [[Atorvastatin]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Niaspan® || [[Niacin]] ||
| Mevacor<sup>®</sup> || [[Lovastatin]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Pravachol® || [[Pravastatin]] ||
| Niaspan<sup>®</sup> || [[Niacin]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Pravigard® || [[Pravastatin]] + [[Aspirin]] ||
| Pravachol<sup>®</sup> || [[Pravastatin]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Vytorin® || [[Ezetimibe]] + [[Simvastatin]] ||
| Pravigard<sup>®</sup> || [[Pravastatin]] + [[Aspirin]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Zocor® || [[Simvastatin]] ||
| Vytorin<sup>®</sup> || [[Ezetimibe]] + [[Simvastatin]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| Infections || Acrodantin® || [[Nitrofurantoin]] || rowspan=7 valign="top" | Fast heartbeat, sudden changes in blood pressure; stomach pain, upset stomach, vomiting, headache, or flushing or redness of the face; liver damage (isoniazid, ketoconazole)
| Zocor<sup>®</sup> || [[Simvastatin]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Flagyl® || [[Metronidazole]] ||
| rowspan=7 valign="top" | Infections || Acrodantin<sup>®</sup> || [[Nitrofurantoin]] || rowspan=7 valign="top" | Fast heartbeat, sudden changes in blood pressure; stomach pain, upset stomach, vomiting, headache, or flushing or redness of the face; liver damage (isoniazid, ketoconazole)
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Grisactin® || [[Griseofulvin]] ||
| Flagyl<sup>®</sup> || [[Metronidazole]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Nizoral® || [[Ketoconazole]] ||
| Grisactin<sup>®</sup> || [[Griseofulvin]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Nydrazid® || [[Isoniazid]] ||
| Nizoral<sup>®</sup> || [[Ketoconazole]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Seromycin® || [[Cycloserine]] ||
| Nydrazid<sup>®</sup> || [[Isoniazid]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Tindamax® || [[Tinidazole]] ||
| Seromycin<sup>®</sup> || [[Cycloserine]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| Muscle pain || Flexeril® || [[Cyclobenzaprine]] || Drowsiness, dizziness; increased risk of seizures; increased risk for overdose; slowed or difficulty breathing; impaired motor control; unusual behavior; memory problems
| Tindamax<sup>®</sup> || [[Tinidazole]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Soma® || [[Carisoprodol]] ||
| rowspan=2 valign="top" | Muscle pain || Flexeril<sup>®</sup> || [[Cyclobenzaprine]] || rowspan=2 valign="top" | Drowsiness, dizziness; increased risk of seizures; increased risk for overdose; slowed or difficulty breathing; impaired motor control; unusual behavior; memory problems
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| Nausea, motion sickness || Antivert® || [[Meclizine]] || rowspan=4 valign="top" | Drowsiness, dizziness; increased risk for overdose
| valign="top" | Soma<sup>®</sup> || valign="top" | [[Carisoprodol]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Atarax® || [[Hydroxyzine]] ||
| rowspan=4 valign="top" | Nausea, motion sickness || Antivert<sup>®</sup> || [[Meclizine]] || rowspan=4 valign="top" | Drowsiness, dizziness; increased risk for overdose
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Dramamine® || [[Dimenhydrinate]] ||
| Atarax<sup>®</sup> || [[Hydroxyzine]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Phenergan® || [[Promethazine]] ||
| Dramamine<sup>®</sup> || [[Dimenhydrinate]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| Pain (such as headache, muscle ache, minor arthritis pain), fever, inflammation || Advil® || [[Ibuprofen]] || rowspan=5 valign="top" | Stomach upset, bleeding and ulcers; liver damage (acetaminophen); rapid heartbeat
| Phenergan<sup>®</sup> || [[Promethazine]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Aleve® || [[Naproxen]] ||
| rowspan=5 valign="top" | Pain (such as headache, muscle ache, minor arthritis pain), fever, inflammation || Advil<sup>®</sup> || [[Ibuprofen]] || rowspan=5 valign="top" | Stomach upset, bleeding and ulcers; liver damage (acetaminophen); rapid heartbeat
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Excedrin® || [[Aspirin]], [[Acetaminophen]] ||
| Aleve<sup>®</sup> || [[Naproxen]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Motrin® || [[Ibuprofen]] ||
| Excedrin<sup>®</sup> || [[Aspirin]], [[Acetaminophen]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Tylenol® || [[Acetaminophen]] ||
| Motrin<sup>®</sup> || [[Ibuprofen]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| Seizures|| Dilantin® || [[Phenytoin]] || rowspan=3 valign="top" | Drowsiness, dizziness; increased risk of seizures
| Tylenol<sup>®</sup> || [[Acetaminophen]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Klonopin® || [[Clonazepam]]
, [[Phenobarbital]] ||
| rowspan=3 valign="top" | Seizures|| Dilantin<sup>®</sup> || [[Phenytoin]] || rowspan=3 valign="top" | Drowsiness, dizziness; increased risk of seizures
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Phenobarbital]] || [[Phenobarbital]] ||
| Klonopin<sup>®</sup> || [[Clonazepam]]
, [[Phenobarbital]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| Severe pain from injury, postsurgical care, oral surgery, migraines|| Darvocet–N® || [[Propoxyphene]] || rowspan=5 valign="top" | Drowsiness, dizziness; increased risk for overdose; slowed or difficulty breathing; impaired motor control; unusual behavior; memory problems
| Phenobarbital || [[Phenobarbital]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Demerol® || [[Meperidine]] ||
| rowspan=5 valign="top" | Severe pain from injury, postsurgical care, oral <BR> surgery, migraines|| Darvocet–N<sup>®</sup> || [[Propoxyphene]] || rowspan=5 valign="top" | Drowsiness, dizziness; increased risk for overdose; slowed or difficulty breathing; impaired motor control; unusual behavior; memory problems
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Fiorinal® with codeine || [[Butalbital]] + [[Codeine]] ||
| Demerol<sup>®</sup> || [[Meperidine]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Percocet® || [[Oxycodone]] ||
| Fiorinal<sup>®</sup> with codeine || [[Butalbital]] + [[Codeine]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Vicodin® || [[Hydrocodone]] ||
| Percocet<sup>®</sup> || [[Oxycodone]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| Sleep problems || Ambien® || [[Zolpidem]] || rowspan=6 valign="top" | Drowsiness, sleepiness, dizziness; slowed or difficulty breathing; impaired motor control; unusual behavior; memory problems
| Vicodin<sup>®</sup> || [[Hydrocodone]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Lunesta® || [[Eszopiclone]] ||
| rowspan=7 valign="top" | Sleep problems || Ambien<sup>®</sup> || [[Zolpidem]] || rowspan=6 valign="top" | Drowsiness, sleepiness, dizziness; slowed or difficulty breathing; impaired motor control; unusual behavior; memory problems
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Prosom® || [[Estazolam]] ||
| Lunesta<sup>®</sup> || [[Eszopiclone]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Restoril® || [[Temazepam]] ||
| Prosom<sup>®</sup> || [[Estazolam]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Sominex® || [[Diphenhydramine]] ||
| Restoril<sup>®</sup> || [[Temazepam]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Unisom® || [[Doxylamine]] ||
| Sominex<sup>®</sup> || [[Diphenhydramine]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| || Herbal preparations (chamomile, valerian, lavender) || — || Increased drowsiness
| Unisom<sup>®</sup> || [[Doxylamine]]
|-style="background: #EFEFEF;"
|-style="background: #EFEFEF;"
| Herbal preparations <BR> (chamomile, valerian, lavender) || valign="top" | — || valign="top" | Increased drowsiness
|-
|}
|}


Latest revision as of 17:19, 20 February 2014

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

The most common medications reported to interact with alcohol are antibiotics, antidepressants, antihistamines, barbiturates, benzodiazepines, H2 blockers, muscle relaxants, opioids, and warfarin. Alcohol may affect pharmacodynamics and/or pharmacokinetics of medications and result in altered therapeutic effects as well as adverse reactions.

Commonly Used Medicines (Both Prescription and Over-The-Counter) That Interact With Alcohol

Commonly Used Medicines (Both Prescription and Over-The-Counter) That Interact With Alcohol[1]
Symptom/Disorders Medication
(Trade Name) 		Medication
(Generic Name) 		Possible Reactions With Alcohol
Allergies/Colds/Flu Alavert® Loratadine Drowsiness, dizziness; increased risk for overdose
Allegra®, Allegra-D® Fexofenadine
Benadryl® Diphenhydramine
Clarinex® Desloratadine
Claritin®, Claritin-D® Loratadine
Dimetapp® Cold & Allergy Brompheniramine
Sudafed® Sinus & Allergy Chlorpheniramine
Triaminic® Cold & Allergy Chlorpheniramine
Tylenol® Allergy Sinus Chlorpheniramine
Tylenol® Cold & Flu Chlorpheniramine
Zyrtec® Cetirizine
Angina (chest pain),
coronary heart disease		 Isordil® Isosorbide Rapid heartbeat, sudden changes in blood pressure, dizziness, fainting
Nitroglycerin
Anxiety and epilepsy Ativan® Lorazepam Drowsiness, dizziness; increased risk for overdose; slowed or difficulty breathing; impaired motor control; unusual behavior; and memory problems
Klonopin® Clonazepam
Librium® Chlordiazepoxide
Paxil® Paroxetine
Valium® Diazepam
Xanax® Alprazolam
Herbal preparations (Kava Kava) — Liver damage, drowsiness
Arthritis Celebrex® Celecoxib Ulcers, stomach bleeding, liver problems
Naprosyn® Naproxen
Voltaren® Diclofenac
Blood clots Coumadin® Warfarin Occasional drinking may lead to internal bleeding; heavier drinking also may cause bleeding or may have the opposite effect, resulting in possible blood clots, strokes, or heart attacks
Cough Delsym®, Robitussin Cough® Dextromethorphan Drowsiness, dizziness; increased risk for overdose
Robitussin A–C® Guaifenesin + Codeine
Depression Anafranil® Clomipramine Drowsiness, dizziness; increased risk for overdose; increased feelings of depression or hopelessness in adolescents (suicide)
Celexa® Citalopram
Desyrel® Trazodone
Effexor® Venlafaxine
Elavil® Amitriptyline
Lexapro® Escitalopram
Luvox® Fluvoxamine
Norpramin® Desipramine
Paxil® Paroxetine
Prozac® Fluoxetine
Serzone® Nefazodone
Wellbutrin® Bupropion
Zoloft® Sertraline
St. John’s Wort —
Diabetes Glucophage® Metformin Abnormally low blood sugar levels, flushing reaction (nausea, vomiting, headache, rapid heartbeat, sudden changes in blood pressure)
Micronase® Glyburide
Orinase® Tolbutamide
Enlarged prostate Cardura® Doxazosin Dizziness, light headedness, fainting
Flomax® Tamsulosin
Hytrin® Terazosin
Minipress® Prazosin
Heartburn, indigestion,
sour stomach		 Axid® Nizatidine Rapid heartbeat, sudden changes in blood pressure (metoclopramide); increased alcohol effect
Reglan® Metoclopramide
Tagamet® Cimetidine
Zantac® Ranitidine
High blood pressure Accupril® Quinapril Dizziness, fainting, drowsiness; heart problems such as changes in the heart’s regular heartbeat (arrhythmia)
Capozide® Hydrochlorothiazide
Cardura® Doxazosin
Catapres® Clonidine
Cozaar® Losartan
Hytrin® Terazosin
Lopressor® HCT Hydrochlorothiazide
Lotensin® Benzapril
Minipress® Prazosin
Vaseretic® Enalapril
High cholesterol Advicor® Lovastatin + Niacin Liver damage (all medications); increased flushing and itching (niacin), increased stomach bleeding (pravastatin + aspirin)
Altocor® Lovastatin
Crestor® Rosuvastatin
Lipitor® Atorvastatin
Mevacor® Lovastatin
Niaspan® Niacin
Pravachol® Pravastatin
Pravigard® Pravastatin + Aspirin
Vytorin® Ezetimibe + Simvastatin
Zocor® Simvastatin
Infections Acrodantin® Nitrofurantoin Fast heartbeat, sudden changes in blood pressure; stomach pain, upset stomach, vomiting, headache, or flushing or redness of the face; liver damage (isoniazid, ketoconazole)
Flagyl® Metronidazole
Grisactin® Griseofulvin
Nizoral® Ketoconazole
Nydrazid® Isoniazid
Seromycin® Cycloserine
Tindamax® Tinidazole
Muscle pain Flexeril® Cyclobenzaprine Drowsiness, dizziness; increased risk of seizures; increased risk for overdose; slowed or difficulty breathing; impaired motor control; unusual behavior; memory problems
Soma® Carisoprodol
Nausea, motion sickness Antivert® Meclizine Drowsiness, dizziness; increased risk for overdose
Atarax® Hydroxyzine
Dramamine® Dimenhydrinate
Phenergan® Promethazine
Pain (such as headache, muscle ache, minor arthritis pain), fever, inflammation Advil® Ibuprofen Stomach upset, bleeding and ulcers; liver damage (acetaminophen); rapid heartbeat
Aleve® Naproxen
Excedrin® Aspirin, Acetaminophen
Motrin® Ibuprofen
Tylenol® Acetaminophen
Seizures Dilantin® Phenytoin Drowsiness, dizziness; increased risk of seizures
Klonopin® Clonazepam
, Phenobarbital
Phenobarbital Phenobarbital
Severe pain from injury, postsurgical care, oral
surgery, migraines		 Darvocet–N® Propoxyphene Drowsiness, dizziness; increased risk for overdose; slowed or difficulty breathing; impaired motor control; unusual behavior; memory problems
Demerol® Meperidine
Fiorinal® with codeine Butalbital + Codeine
Percocet® Oxycodone
Vicodin® Hydrocodone
Sleep problems Ambien® Zolpidem Drowsiness, sleepiness, dizziness; slowed or difficulty breathing; impaired motor control; unusual behavior; memory problems
Lunesta® Eszopiclone
Prosom® Estazolam
Restoril® Temazepam
Sominex® Diphenhydramine
Unisom® Doxylamine
Herbal preparations
(chamomile, valerian, lavender)		 — Increased drowsiness

References

  1. ↑ "http://pubs.niaaa.nih.gov/publications/Medicine/medicine.htm". External link in |title= (help)
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