Candesartan overdosage: Difference between revisions

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(Redirected page to Candesartan#Overdosage)
 
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#REDIRECT [[Candesartan#Overdosage]]
{{Candesartan}}
{{CMG}}; {{AE}} {{SS}}
 
==Overdosage==
 
No lethality was observed in acute toxicity studies in mice, rats, and dogs given single oral doses of up to 2000 mg/kg of candesartan cilexetil. In mice given single oral doses of the primary metabolite, candesartan, the minimum lethal dose was greater than 1000 mg/kg but less than 2000 mg/kg.
 
The most likely manifestation of overdosage with ATACAND would be [[hypotension]], [[dizziness]], and [[tachycardia]]; [[bradycardia]] could occur from parasympathetic (vagal) stimulation. If symptomatic hypotension should occur, supportive treatment should be instituted.
 
Candesartan cannot be removed by [[hemodialysis]].
 
'''Treatment''': To obtain up-to-date information about the treatment of overdose, consult your Regional Poison Control Center. Telephone numbers of certified poison control centers are listed in the Physicians’ Desk Reference (PDR). In managing overdose, consider the possibilities of multiple-drug overdoses, drug-drug interactions, and altered pharmacokinetics in your patient.<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = ATACAND (CANDESARTAN CILEXETIL) TABLET [ASTRAZENECA LP] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=a73e1339-9643-4eea-2cbe-e879c88fb50e | publisher =  | date =  | accessdate = 20 February 2014 }}</ref>
 
 
==References==
{{Reflist}}
 
{{Angiotensin II receptor antagonists}}
 
[[Category:Angiotensin II receptor antagonists]]
[[Category:Tetrazoles]]
[[Category:Benzimidazoles]]
[[Category:Ethers]]
[[Category:Carboxylic acids]]
[[Category:Biphenyls]]
[[Category:Cardiovascular Drugs]]
[[Category:Drugs]]

Latest revision as of 23:28, 21 July 2014