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| __NOTOC__
| | #REDIRECT [[Amiloride#Overdosage]] |
| {{Amiloride}}
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| {{CMG}}; {{AE}} {{SS}}
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| ==Overdosage==
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| No data are available in regard to overdosage in humans.
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| The oral LD50 of amiloride hydrochloride (calculated as the base) is 56 mg/kg in mice and 36 to 85 mg/kg in rats, depending on the strain.
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| It is not known whether the drug is dialyzable.
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| The most likely signs and symptoms to be expected with overdosage are dehydration and electrolyte imbalance. These can be treated by established procedures. Therapy with MIDAMOR should be discontinued and the patient observed closely. There is no specific antidote. Emesis should be induced or gastric lavage performed. Treatment is symptomatic and supportive. If [[hyperkalemia]] occurs, active measures should be taken to reduce the serum potassium levels.<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = MIDAMOR (AMILORIDE HYDROCHLORIDE) TABLET [PADDOCK LABORATORIES, INC.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=f4cde6e4-12cb-4e30-920f-5b94576b4863 | publisher = | date = | accessdate = 26 February 2014 }}</ref>
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| ==References==
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| {{reflist|2}}
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| {{Sodium channel blockers}}
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| {{Diuretics}}
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| [[Category:Potassium-sparing diuretics]]
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| [[Category:Aminopyrazines]]
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| [[Category:Guanidines]]
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| [[Category:World Health Organization essential medicines]]
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| [[Category:Cardiovascular Drugs]]
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| [[Category:Drugs]]
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