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Gerald Chi (talk | contribs)
CMEAdmin, Bureaucrats, bureaucrats, editnews, exportpages, interwiki, nocaptcha, nukepages, smwadministrator, Administrators, Widget editors
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==Treatment of Thymoma and Thymic Carcinoma==
==Treatment of Thymoma and Thymic Carcinoma==
{{thymoma}}


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<div style="border-radius: 5px 5px 0 0; border: solid 1px #20538D; border-bottom: 0px; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: inset 0 1px 1px rgba(255, 255, 255, 0.5), 0 1px 1px rgba(0, 0, 0, 0.5); height: 30px; line-height: 30px; width: 150px; background: #A1BCDD; text-align: center;">
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</div>
</div>


<div class="mw-customtoggle-table02" style="cursor: pointer; border-radius: 0 0 0 0; border: solid 1px #20538D; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: inset 0 1px 1px rgba(255, 255, 255, 0.5), 0 1px 1px rgba(0, 0, 0, 0.5); height: 30px; line-height: 30px; width: 150px; background: #4479BA;">
<div class="mw-customtoggle-table-resectable" style="cursor: pointer; border-radius: 0 0 0 0; border: solid 1px #20538D; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: inset 0 1px 1px rgba(255, 255, 255, 0.5), 0 1px 1px rgba(0, 0, 0, 0.5); height: 30px; line-height: 30px; width: 150px; background: #4479BA;">
<font color="#FFF">
<font color="#FFF">
&nbsp;&nbsp;▸&nbsp;&nbsp;'''Resectable'''
&nbsp;&nbsp;▸&nbsp;&nbsp;'''Resectable'''
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</div>
</div>


<div class="mw-customtoggle-table01" style="cursor: pointer; border-radius: 0 0 5px 5px; border: solid 1px #20538D; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: inset 0 1px 1px rgba(255, 255, 255, 0.5), 0 1px 1px rgba(0, 0, 0, 0.5); height: 30px; line-height: 30px; width: 150px; background: #4479BA;">
<div class="mw-customtoggle-table-Unresectable" style="cursor: pointer; border-radius: 0 0 5px 5px; border: solid 1px #20538D; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: inset 0 1px 1px rgba(255, 255, 255, 0.5), 0 1px 1px rgba(0, 0, 0, 0.5); height: 30px; line-height: 30px; width: 150px; background: #4479BA;">
<font color="#FFF">
<font color="#FFF">
&nbsp;&nbsp;▸&nbsp;&nbsp;'''Unresectable'''
&nbsp;&nbsp;▸&nbsp;&nbsp;'''Unresectable'''
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<table class="mw-collapsible mw-collapsed" id="mw-customcollapsible
<table class="mw-collapsible mw-collapsed"
</table>
</table>


<table class="mw-collapsible mw-collapsed" id="mw-customcollapsible-table-Unresectable" style="background: #FFFFFF; float: left; cellpadding=0; cellspacing= 0; width: 400px;" cellspacing="0" cellpadding="0" border="0">
<tr align="center"><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="6" rowspan="2" style="border: 2px solid black; padding: 0.2em; background: WhiteSmoke;;"><div style="float: left; text-align: center; height: 4.5em; width: 11em; padding: 1em; font-size: 100%">Thymoma or Thymic Carcinoma</div></td></tr><tr align="center"></tr>
<tr align="center"><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td><div style="width:1em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td style="border-bottom:1px solid black"><div style="width:1em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2" style="border-bottom:1px solid black"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2" style="border-bottom:1px solid black"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2" style="border-bottom:1px solid black"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2" style="border-bottom:1px solid black"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2" style="border-bottom:1px solid black"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2" style="border-bottom:1px solid black"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td style="border-right:1px solid black;border-bottom:1px solid black"><div style="width:1em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td style="border-bottom:1px solid black"><div style="width:1em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2" style="border-bottom:1px solid black"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2" style="border-bottom:1px solid black"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2" style="border-bottom:1px solid black"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2" style="border-bottom:1px solid black"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2" style="border-bottom:1px solid black"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2" style="border-bottom:1px solid black"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td style="border-bottom:1px solid black"><div style="width:1em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2"><div style="width:1em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td></tr><tr align="center"><td style="border-right:1px solid black"><div style="width:1em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td><div style="width:1em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td style="border-right:1px solid black"><div style="width:1em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td><div style="width:1em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td style="border-right:1px solid black"><div style="width:1em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td></tr>
<tr align="center"><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="6" rowspan="2" style="border: 2px solid black; padding: 0.2em; background: WhiteSmoke;;"><div style="float: left; text-align: center; height: 1.25em; width: 10em; padding: 1em;">Locally Advanced</div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="6" rowspan="2" style="border: 2px solid black; padding: 0.2em; background: WhiteSmoke;;"><div style="float: left; text-align: center; height: 1.25em; width: 11em; padding: 1em;">Solitary Metastasis</div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="6" rowspan="2" style="border: 2px solid black; padding: 0.2em; background: WhiteSmoke;;"><div style="float: left; text-align: center; height: 1.25em; width: 10em; padding: 1em;">Distant metastasis</div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td></tr><tr align="center"></tr>
<tr align="center"><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" style="border-right:1px solid black"><div style="width:1em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2"><div style="width:1em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td><div style="width:1em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td style="border-bottom:1px solid black"><div style="width:1em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2" style="border-bottom:1px solid black"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2" style="border-bottom:1px solid black"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td style="border-right:1px solid black;border-bottom:1px solid black"><div style="width:1em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td style="border-bottom:1px solid black"><div style="width:1em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2" style="border-bottom:1px solid black"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2" style="border-bottom:1px solid black"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td style="border-bottom:1px solid black"><div style="width:1em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2"><div style="width:1em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" style="border-right:1px solid black"><div style="width:1em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2"><div style="width:1em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td></tr><tr align="center"><td style="border-right:1px solid black"><div style="width:1em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td><div style="width:1em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td style="border-right:1px solid black"><div style="width:1em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td></tr>
<tr align="center"><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="6" rowspan="2" style="border: 2px solid black; padding: 0.2em; background: WhiteSmoke;;"><div style="float: left; text-align: center; height: 1.25em; width: 10em; padding: 1em;"><b>[[Thymoma_treatment#Chemotherapy_Regimens|Chemotherapy]]</b></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="6" rowspan="2" style="border: 2px solid black; padding: 0.2em; background: WhiteSmoke;;"><div style="float: left; text-align: center; height: 1.25em; width: 10em; padding: 1em;"><b>[[Thymoma_treatment#Chemotherapy_Regimens|Chemotherapy]]</b></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="6" rowspan="2" style="border: 2px solid black; padding: 0.2em; background: WhiteSmoke;;"><div style="float: left; text-align: center; height: 1.25em; width: 10em; padding: 1em;">Surgery</div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="6" rowspan="2" style="border: 2px solid black; padding: 0.2em; background: WhiteSmoke;;"><div style="float: left; text-align: center; height: 1.25em; width: 10em; padding: 1em;"><b>[[Thymoma_treatment#Chemotherapy_Regimens|Chemotherapy]]</b></div></td></tr><tr align="center"></tr>
<tr align="center"><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td style="border-right:1px solid black"><div style="width:1em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td style="border-bottom:1px solid black"><div style="width:1em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2" style="border-bottom:1px solid black"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2" style="border-bottom:1px solid black"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2" style="border-bottom:1px solid black"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td style="border-right:1px solid black;border-bottom:1px solid black"><div style="width:1em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td><div style="width:1em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" style="border-right:1px solid black"><div style="width:1em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2"><div style="width:1em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td></tr><tr align="center"><td colspan="2"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td style="border-right:1px solid black"><div style="width:1em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td><div style="width:1em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td></tr>
<tr align="center"><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="6" rowspan="2" style="border: 2px solid black; padding: 0.2em; background: WhiteSmoke;;"><div style="float: left; text-align: center; height: 2.5em; width: 10em; padding: 1em;">Re-evaluate <br /> for surgery</div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="6" rowspan="2" style="border: 2px solid black; padding: 0.2em; background: WhiteSmoke;;"><div style="float: left; text-align: center; height: 1.25em; width: 10em; padding: 1em;"><b>[[Thymoma_treatment#Chemotherapy_Regimens|Chemotherapy]]</b> or <b>'''[[Thymoma treatment#Radiation Dose|RT]]'''</b></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td></tr><tr align="center"></tr>
<tr align="center"><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td><div style="width:1em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td style="border-bottom:1px solid black"><div style="width:1em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2" style="border-bottom:1px solid black"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td style="border-right:1px solid black;border-bottom:1px solid black"><div style="width:1em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td style="border-bottom:1px solid black"><div style="width:1em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2" style="border-bottom:1px solid black"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td style="border-bottom:1px solid black"><div style="width:1em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2"><div style="width:1em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td></tr><tr align="center"><td style="border-right:1px solid black"><div style="width:1em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td><div style="width:1em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="2"><div style="width:2em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td><td style="border-right:1px solid black"><div style="width:1em;height:1em"><span style="font:1px/1px serif">&#160;</span></div></td></tr>
<tr align="center"><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="6" rowspan="2" style="border: 2px solid black; padding: 0.2em; background: WhiteSmoke;;"><div style="float: left; text-align: center; height: 1.25em; width: 10em; padding: 1em;">Resectable</div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="6" rowspan="2" style="border: 2px solid black; padding: 0.2em; background: WhiteSmoke;;"><div style="float: left; text-align: center; height: 1.25em; width: 10em; padding: 1em;">Unresectable</div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td></tr><tr align="center"></tr>
<tr align="center"><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" style="border-right:1px solid black"><div style="width:1em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2"><div style="width:1em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" style="border-right:1px solid black"><div style="width:1em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2"><div style="width:1em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td></tr><tr align="center"></tr>
<tr align="center"><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="6" rowspan="2" style="border: 2px solid black; padding: 0.2em; background: WhiteSmoke;;"><div style="float: left; text-align: center; height: 2.5em; width: 10em; padding: 1em;">Surgery ± <br />  Postoperative <b>'''[[Thymoma treatment#Radiation Dose|RT]]'''</b></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td><td colspan="6" rowspan="2" style="border: 2px solid black; padding: 0.2em; background: WhiteSmoke;;"><div style="float: left; text-align: center; height: 1.25em; width: 10em; padding: 1em;"><b>'''[[Thymoma treatment#Radiation Dose|RT]]'''</b> ± <b>[[Thymoma_treatment#Chemotherapy_Regimens|Chemotherapy]]</b></div></td><td rowspan="2" colspan="2"><div style="width:2em;height:2em"><span style="font:1px/1px serif">&#160;</span></div></td></tr><tr align="center"></tr>
</table>


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<table class="mw-collapsible mw-collapsed" id="mw-customcollapsible-table02" style="background: #FFFFFF; float: left; cellpadding=0; cellspacing= 0; width: 400px;" cellspacing="0" cellpadding="0" border="0">
====Chemotherapy Regimens====
<tr align="center"><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="6" rowspan="2" style="border: 2px solid black; padding: 0.2em;&#160;;">Pathology evaluation</td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td></tr><tr align="center"></tr>


<tr align="center"><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td style="border-bottom: 1px solid black;"><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2" style="border-bottom: 1px solid black;"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2" style="border-bottom: 1px solid black;"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2" style="border-bottom: 1px solid black;"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2" style="border-bottom: 1px solid black;"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2" style="border-bottom: 1px solid black;"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2" style="border-bottom: 1px solid black;"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2" style="border-bottom: 1px solid black;"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2" style="border-bottom: 1px solid black;"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td style="border-right: 1px solid black; border-bottom: 1px solid black;"><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td style="border-bottom: 1px solid black;"><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2" style="border-bottom: 1px solid black;"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2" style="border-bottom: 1px solid black;"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2" style="border-bottom: 1px solid black;"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2" style="border-bottom: 1px solid black;"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2" style="border-bottom: 1px solid black;"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2" style="border-bottom: 1px solid black;"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2" style="border-bottom: 1px solid black;"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2" style="border-bottom: 1px solid black;"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2" style="border-bottom: 1px solid black;"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td style="border-bottom: 1px solid black;"><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td></tr><tr align="center"><td style="border-right: 1px solid black;"><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td style="border-right: 1px solid black;"><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td style="border-right: 1px solid black;"><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td></tr>
<B><small>[[Thymoma treatment#Approach to Thymoma and Thymic Carcinoma|Return to top]]</small></B>


<tr align="center"><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="6" rowspan="2" style="border: 2px solid black; padding: 0.2em;&#160;;">R0 Resection</td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="6" rowspan="2" style="border: 2px solid black; padding: 0.2em;&#160;;">R2 Resection</td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="6" rowspan="2" style="border: 2px solid black; padding: 0.2em;&#160;;">R1 Resection</td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td></tr><tr align="center"></tr>
{| {{table}}
| align="center" style="background:#f0f0f0;" colspan=2|'''FIRST-LINE COMBINATION CHEMOTHERAPY REGIMENS'''
| align="center" style="background:#f0f0f0;"|'''SECOND-LINE CHEMOTHERAPY'''
|-
| '''CAP''' (preferred for thymoma) <BR> * Cisplatin 50 mg/m² IV day 1  <BR> * Doxorubicin 50 mg/m² IV day 1 <BR> * Cyclophosphamide 500 mg/m² IV day 1 <BR>   Administered every 3 weeks|| '''PE''' <BR> * Cisplatin 60 mg/m² IV day 1 <BR> *Etoposide 120 mg/m²/d IV days 1  -3 <BR> Administered every 3 weeks||rowspan=3 valign=top|Etoposide <BR> Ifosfamide <BR> Pemetrexed <BR> Octreotide (including LAR) + prednisone <BR> 5-FU and leucovirin <BR> Gemcitabine    <BR> Paclitaxel
|-
| '''CAP with Prednisone'''  <BR> * Cisplatin 30 mg/m² IV days 1-3 <BR> * Doxorubicin 20 mg/m²/d <BR> IV continuous infusion on days 1 to 3 <BR> * Cyclophosphamide 500 mg/m² IV on day 1 <BR> * Prednisone 100 mg/day on days 1-5 <BR> Administered every 3 weeks||'''VIP''' <BR> * Etoposide 75 mg/m² on days 1-4 <BR>* Ifosfamide 1.2 g/m² on days 1-4  <BR> * Cisplatin 20 mg/m² on days 1-4 <BR> Administered every 3  weeks
|-
| '''ADOC'''  <BR> * Cisplatin 50 mg/m² IV day 1 <BR> * Doxorubicin 40 mg/m² IV day 1  <BR> * Vincristine 0.6 mg/m² IV day 3  <BR> * Cyclophosphamide 700 mg/m² IV day 4 <BR> Administered every 3 weeks || '''Carboplatin/Paclitaxel''' (preferred for Thymic Carcinoma) <BR>* Carboplatin AUC 6 <BR> *  Paclitaxel 225 mg/m² <BR> Administered every 3 weeks
|-
|}


<tr align="center"><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td style="border-bottom: 1px solid black;"><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td style="border-right: 1px solid black; border-bottom: 1px solid black;"><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td style="border-bottom: 1px solid black;"><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td style="border-bottom: 1px solid black;"><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td style="border-bottom: 1px solid black;"><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td style="border-right: 1px solid black; border-bottom: 1px solid black;"><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td style="border-bottom: 1px solid black;"><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td style="border-bottom: 1px solid black;"><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td style="border-bottom: 1px solid black;"><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td style="border-right: 1px solid black; border-bottom: 1px solid black;"><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td style="border-bottom: 1px solid black;"><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td style="border-bottom: 1px solid black;"><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td></tr><tr align="center"><td style="border-right: 1px solid black;"><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td style="border-right: 1px solid black;"><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td style="border-right: 1px solid black;"><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td style="border-right: 1px solid black;"><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td style="border-right: 1px solid black;"><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td style="border-right: 1px solid black;"><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td></tr>
====Radiation Dose====


<tr align="center"><td colspan="6" rowspan="2" style="border: 2px solid black; padding: 0.2em;&#160;;">Thymoma, no capsular invasion or thymic carcinoma,stage I</td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="6" rowspan="2" style="border: 2px solid black; padding: 0.2em;&#160;;">Thymoma or thymic carcinoma, capsular invasion presents stages II-IV</td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="6" rowspan="2" style="border: 2px solid black; padding: 0.2em;&#160;;">Thymoma</td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="6" rowspan="2" style="border: 2px solid black; padding: 0.2em;&#160;;">Thymic carcinoma</td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="6" rowspan="2" style="border: 2px solid black; padding: 0.2em;&#160;;">Thymoma</td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="6" rowspan="2" style="border: 2px solid black; padding: 0.2em;&#160;;">Thymic carcinoma</td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td></tr><tr align="center"></tr>
<B><small>[[Thymoma treatment#Approach to Thymoma and Thymic Carcinoma|Return to top]]</small></B>


<tr align="center"><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" style="border-right: 1px solid black;"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" style="border-right: 1px solid black;"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" style="border-right: 1px solid black;"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" style="border-right: 1px solid black;"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" style="border-right: 1px solid black;"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" style="border-right: 1px solid black;"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td></tr><tr align="center"></tr>
* A dose of 60-70 Gy should be given to patients with unresectable disease.


<tr align="center"><td colspan="6" rowspan="2" style="border: 2px solid black; padding: 0.2em;&#160;;">Surveillance for recurrence with CT every 6 month for 2 y, then annually every 5 y for thymic carcinoma and 10 y for thymoma</td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="6" rowspan="2" style="border: 2px solid black; padding: 0.2em;&#160;;">Consider postoperative RT</td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="6" rowspan="2" style="border: 2px solid black; padding: 0.2em;&#160;;">Postoperative RT</td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="6" rowspan="2" style="border: 2px solid black; padding: 0.2em;&#160;;">Postoperative RT+chemotherapy</td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="6" rowspan="2" style="border: 2px solid black; padding: 0.2em;&#160;;">RT +/- chemotherapy</td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="6" rowspan="2" style="border: 2px solid black; padding: 0.2em;&#160;;">RT +/- chemotherapy</td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td></tr><tr align="center"></tr>
* For adjuvant treatment, the radiation dose consists of 45-50 Gy for clear/close margins and 54 Gy for microscopically positive resection margins. A total dose of 60 Gy and above should be given to patients with gross residual disease (similar to patients with unresectable disease), when conventional fractionation (1.8 to 2.0 Gy per daily fraction) is applied.
 
<tr align="center"><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" style="border-right: 1px solid black;"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" style="border-right: 1px solid black;"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" style="border-right: 1px solid black;"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" style="border-right: 1px solid black;"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" style="border-right: 1px solid black;"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" style="border-right: 1px solid black;"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"></td></tr><tr align="center"></tr>
 
<tr align="center"><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" style="border-right: 1px solid black;"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td style="border-right: 1px solid black;"><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td style="border-bottom: 1px solid black;"><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2" style="border-bottom: 1px solid black;"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2" style="border-bottom: 1px solid black;"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2" style="border-bottom: 1px solid black;"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2" style="border-bottom: 1px solid black;"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2" style="border-bottom: 1px solid black;"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td style="border-right: 1px solid black; border-bottom: 1px solid black;"><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td style="border-bottom: 1px solid black;"><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2" style="border-bottom: 1px solid black;"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2" style="border-bottom: 1px solid black;"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="6" rowspan="2" style="border: 2px solid black; padding: 0.2em;&#160;;">Surveillance for recurrence with CT every 6 month for 2 y, then annually every 5 y for thymic carcinoma and 10 y for thymoma</td><td colspan="2" style="border-bottom: 1px solid black;"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2" style="border-bottom: 1px solid black;"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2" style="border-bottom: 1px solid black;"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2" style="border-bottom: 1px solid black;"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td style="border-right: 1px solid black; border-bottom: 1px solid black;"><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td style="border-bottom: 1px solid black;"><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2" style="border-bottom: 1px solid black;"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2" style="border-bottom: 1px solid black;"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2" style="border-bottom: 1px solid black;"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td style="border-right: 1px solid black; border-bottom: 1px solid black;"><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td><div style="width: 1em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td></tr><tr align="center"><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="2"><div style="width: 2em; height: 1em;"><span style="font: 1px/1px serif;">&#160;</span></div></td></tr>
 
<tr align="center"><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" style="border-right: 1px solid black;"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" style="border-right: 1px solid black;"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"></td></tr><tr align="center"></tr>
 
<tr align="center"><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" style="border-right: 1px solid black;"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" style="border-right: 1px solid black;"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2"><div style="width: 1em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"></td></tr><tr align="center"></tr>
 
<tr align="center"><td colspan="6" rowspan="2" style="border: 2px solid black; padding: 0.2em;&#160;;">Relapse(check recurrence algorithm)</td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td colspan="6" rowspan="2" style="border: 2px solid black; padding: 0.2em;&#160;;">Relapse(check recurrence algorithm)</td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td><td rowspan="2" colspan="2"><div style="width: 2em; height: 2em;"><span style="font: 1px/1px serif;">&#160;</span></div></td></tr><tr align="center"></tr>
 
</table>

Latest revision as of 21:59, 27 February 2014

Treatment of Thymoma and Thymic Carcinoma

Thymoma Microchapters

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Thymic Tumor

  ▸  Resectable

  ▸  Unresectable


 
 
 
 
 
 
 
 
 
 
 
 
Pathology Evaluation
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
R0 Resection
 
 
 
 
 
 
 
R1 Resection
 
 
 
 
 
 
 
R2 Resection
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Thymoma, no capsular invasion or thymic carcinoma, stage I
 
Thymoma or thymic carcinoma, capsular invasion present, stages II-IV
 
 
 
Thymoma
 
Thymic carcinoma
 
 
 
Thymoma
 
Thymic carcinoma
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Postoperative RT
 
 
 
Postoperative RT
 
Postoperative RT + Chemotherapy
 
 
 
RT ± Chemotherapy
 
RT + Chemotherapy
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Surveillance for recurrence with CT
every 6 month for 2 y, then annually every 5 y for thymic carcinoma
and 10 y for thymoma
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Thymoma or Thymic Carcinoma
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Locally Advanced
 
 
 
 
Solitary Metastasis
 
 
 
 
Distant metastasis
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Surgery
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Re-evaluate
for surgery
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Resectable
 
Unresectable
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Surgery ±
Postoperative RT
 
 


















































Chemotherapy Regimens

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FIRST-LINE COMBINATION CHEMOTHERAPY REGIMENS SECOND-LINE CHEMOTHERAPY
CAP (preferred for thymoma)
* Cisplatin 50 mg/m² IV day 1
* Doxorubicin 50 mg/m² IV day 1
* Cyclophosphamide 500 mg/m² IV day 1
Administered every 3 weeks		 PE
* Cisplatin 60 mg/m² IV day 1
*Etoposide 120 mg/m²/d IV days 1 -3
Administered every 3 weeks		 Etoposide
Ifosfamide
Pemetrexed
Octreotide (including LAR) + prednisone
5-FU and leucovirin
Gemcitabine
Paclitaxel
CAP with Prednisone
* Cisplatin 30 mg/m² IV days 1-3
* Doxorubicin 20 mg/m²/d
IV continuous infusion on days 1 to 3
* Cyclophosphamide 500 mg/m² IV on day 1
* Prednisone 100 mg/day on days 1-5
Administered every 3 weeks		 VIP
* Etoposide 75 mg/m² on days 1-4
* Ifosfamide 1.2 g/m² on days 1-4
* Cisplatin 20 mg/m² on days 1-4
Administered every 3 weeks
ADOC
* Cisplatin 50 mg/m² IV day 1
* Doxorubicin 40 mg/m² IV day 1
* Vincristine 0.6 mg/m² IV day 3
* Cyclophosphamide 700 mg/m² IV day 4
Administered every 3 weeks		 Carboplatin/Paclitaxel (preferred for Thymic Carcinoma)
* Carboplatin AUC 6
* Paclitaxel 225 mg/m²
Administered every 3 weeks

Radiation Dose

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  • A dose of 60-70 Gy should be given to patients with unresectable disease.
  • For adjuvant treatment, the radiation dose consists of 45-50 Gy for clear/close margins and 54 Gy for microscopically positive resection margins. A total dose of 60 Gy and above should be given to patients with gross residual disease (similar to patients with unresectable disease), when conventional fractionation (1.8 to 2.0 Gy per daily fraction) is applied.
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