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| __NOTOC__
| | #REDIRECT [[Amlodipine#Adult Indications and Dosage]] |
| {{Amlodipine}}
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| {{CMG}}; {{AE}} {{AK}}
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| ==2 Dosage and Administration==
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| ===2.1 Adults===
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| The usual initial antihypertensive oral dose of NORVASC is 5 mg once daily with a maximum dose of 10 mg once daily.
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| Small, fragile, or elderly patients, or patients with hepatic insufficiency may be started on 2.5 mg once daily and this dose may be used when adding NORVASC to other [[antihypertensive]] therapy.
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| Adjust dosage according to each patient's need. In general, titration should proceed over 7 to 14 days so that the physician can fully assess the patient's response to each dose level. Titration may proceed more rapidly, however, if clinically warranted, provided the patient is assessed frequently.
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| The recommended dose for chronic [[stable angina|stable]] or [[vasospastic angina]] is 5–10 mg, with the lower dose suggested in the elderly and in patients with hepatic insufficiency. Most patients will require 10 mg for adequate effect [see [[Amlodipine adverse reactions|Adverse Reactions (6)]]].
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| The recommended dose range for patients with coronary artery disease is 5–10 mg once daily. In clinical studies, the majority of patients required 10 mg [see [[Amlodipine clinical studies|Clinical Studies (14.4)]]].
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| ===2.2 Children===
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| The effective antihypertensive oral dose in pediatric patients ages 6–17 years is 2.5 mg to 5 mg once daily. Doses in excess of 5 mg daily have not been studied in pediatric patients [see [[Amlodipine clinical pharmacology|Clinical Pharmacology (12.4)]], [[Amlodipine clinical studies|Clinical Studies (14.1)]]].<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = NORVASC (AMLODIPINE BESYLATE) TABLET [CARDINAL HEALTH] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=44e5ad27-e062-461a-bdf4-192d852fbc49#nlm42230-3 | publisher = | date = | accessdate = 6 March 2014 }}</ref>
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| ==References==
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| {{Reflist|2}}
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| [[Category:Cardiovascular Drugs]] | | [[Category:Cardiovascular Drugs]] |
| [[Category:Drugs]] | | [[Category:Drugs]] |