Lanoxin tablet/pediatric indications and dosage: Difference between revisions
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__NOTOC__ | |||
{{Lanoxin tablet}} | |||
{{CMG}};{{AE}} {{AK}} | |||
===Heart failure=== | ===Heart failure=== | ||
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'''5-10 years old''' | '''5-10 years old''' | ||
20-45 mcg/kg Administer half the total loading dose initially, | 20-45 mcg/kg Administer half the total loading dose initially, then ¼ the loading dose every 6 to 8 hours twice. | ||
then ¼ the loading dose every 6 to 8 hours twice. | |||
'''>10 year old''' | '''>10 year old''' | ||
| Line 12: | Line 14: | ||
====Maintenence dose:==== | ====Maintenence dose:==== | ||
''' | '''2-5 years''':10-15 mcg/kg/day. | ||
'''5-10 years''': 7-10 mcg/kg/day. | |||
'''More than 10 years''': 3-5 mcg/kg/day | |||
===Off-Label Use (Pediatric) === | |||
====Supraventricular tachycardia, Recurrent; Prophylaxis==== | |||
0.01 mg/kg orally 3 times daily for the first 2 doses, then 0.0035 mg/kg 3 times daily<ref name="Pfammatter-1998">{{Cite journal | last1 = Pfammatter | first1 = JP. | last2 = Stocker | first2 = FP. | title = Re-entrant supraventricular tachycardia in infancy: current role of prophylactic digoxin treatment. | journal = Eur J Pediatr | volume = 157 | issue = 2 | pages = 101-6 | month = Feb | year = 1998 | doi = | PMID = 9504781 }}</ref><ref name="Sanatani-2012">{{Cite journal | last1 = Sanatani | first1 = S. | last2 = Potts | first2 = JE. | last3 = Reed | first3 = JH. | last4 = Saul | first4 = JP. | last5 = Stephenson | first5 = EA. | last6 = Gibbs | first6 = KA. | last7 = Anderson | first7 = CC. | last8 = Mackie | first8 = AS. | last9 = Ro | first9 = PS. | title = The study of antiarrhythmic medications in infancy (SAMIS): a multicenter, randomized controlled trial comparing the efficacy and safety of digoxin versus propranolol for prophylaxis of supraventricular tachycardia in infants. | journal = Circ Arrhythm Electrophysiol | volume = 5 | issue = 5 | pages = 984-91 | month = Oct | year = 2012 | doi = 10.1161/CIRCEP.112.972620 | PMID = 22962431 }}</ref> | |||
====Fetal tachycardia - Supraventricular tachycardia==== | |||
Maternal 0.25 to 0.375 mg PO daily alone or with [[verapamil]].<ref name="Lilja-1984">{{Cite journal | last1 = Lilja | first1 = H. | last2 = Karlsson | first2 = K. | last3 = Lindecrantz | first3 = K. | last4 = Sabel | first4 = KG. | title = Treatment of intrauterine supraventricular tachycardia with digoxin and verapamil. | journal = J Perinat Med | volume = 12 | issue = 3 | pages = 151-4 | month = | year = 1984 | doi = | PMID = 6502442 }}</ref> | |||
{{DrugReflist}} | {{DrugReflist}} | ||
Latest revision as of 19:20, 20 March 2014
| Lanoxin tablet® |
|---|
| Black Box Warning |
Adult Indications and Dosage
|
Pediatric Indications and Dosage
|
| Contraindications |
| Warnings |
Adverse Reactions
|
| Drug Interactions |
Use in Specific Populations
|
Routes and Preparations
|
| IV Compatibility |
| Overdosage |
Pharmacology
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| Clinical Studies |
| How Supplied |
Images
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Patient Information
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| Combined Alcohol Use |
| Look-Alike Drug Names |
| Drug Shortage Status |
| Price |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Abdurahman Khalil, M.D. [2]
Heart failure
Loading dose:
5-10 years old 20-45 mcg/kg Administer half the total loading dose initially, then ¼ the loading dose every 6 to 8 hours twice.
>10 year old 10-15 mcg/kg Administer half the total loading dose initially, then ¼ the loading dose every 6 to 8 hours twice.
Maintenence dose:
2-5 years:10-15 mcg/kg/day.
5-10 years: 7-10 mcg/kg/day.
More than 10 years: 3-5 mcg/kg/day
Off-Label Use (Pediatric)
Supraventricular tachycardia, Recurrent; Prophylaxis
0.01 mg/kg orally 3 times daily for the first 2 doses, then 0.0035 mg/kg 3 times daily[1][2]
Fetal tachycardia - Supraventricular tachycardia
Maternal 0.25 to 0.375 mg PO daily alone or with verapamil.[3]
References
- ↑ Pfammatter, JP.; Stocker, FP. (1998). "Re-entrant supraventricular tachycardia in infancy: current role of prophylactic digoxin treatment". Eur J Pediatr. 157 (2): 101–6. PMID 9504781. Unknown parameter
|month=ignored (help) - ↑ Sanatani, S.; Potts, JE.; Reed, JH.; Saul, JP.; Stephenson, EA.; Gibbs, KA.; Anderson, CC.; Mackie, AS.; Ro, PS. (2012). "The study of antiarrhythmic medications in infancy (SAMIS): a multicenter, randomized controlled trial comparing the efficacy and safety of digoxin versus propranolol for prophylaxis of supraventricular tachycardia in infants". Circ Arrhythm Electrophysiol. 5 (5): 984–91. doi:10.1161/CIRCEP.112.972620. PMID 22962431. Unknown parameter
|month=ignored (help) - ↑ Lilja, H.; Karlsson, K.; Lindecrantz, K.; Sabel, KG. (1984). "Treatment of intrauterine supraventricular tachycardia with digoxin and verapamil". J Perinat Med. 12 (3): 151–4. PMID 6502442.