Vincamine: Difference between revisions
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| verifiedrevid = 447608674 | | verifiedrevid = 447608674 | ||
| IUPAC_name = (3α,14β,16α)-14,15-dihydro-<br>14-hydroxyeburnamenine-14-carboxylic acid methyl ester<br />OR<br />methyl (15''R'',17''S'',19''R'')-15-ethyl-17-hydroxy-1,11-diazapentacyclo[9.6.2.0<sup>2,7</sup>.0<sup>8,18</sup>.0<sup>15,19</sup>]nonadeca-2(7),3,5,8(18)-tetraene-17-carboxylate | | IUPAC_name = (3α,14β,16α)-14,15-dihydro-<br>14-hydroxyeburnamenine-14-carboxylic acid methyl ester<br />OR<br />methyl (15''R'',17''S'',19''R'')-15-ethyl-17-hydroxy-1,11-diazapentacyclo[9.6.2.0<sup>2,7</sup>.0<sup>8,18</sup>.0<sup>15,19</sup>]nonadeca-2(7),3,5,8(18)-tetraene-17-carboxylate | ||
| image = Vincamine. | | image = Vincamine.png | ||
| image2 = Vincamine ball-and-stick animation.gif | | image2 = Vincamine ball-and-stick animation.gif | ||
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| molecular_weight = 354.44 g/mol | | molecular_weight = 354.44 g/mol | ||
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==Overview== | |||
'''Vincamine''' is a peripheral [[vasodilator]] that increases blood flow to the brain (sold under the trademark '''Oxybral SR''') . Generic drugs containing vincamine exist in specific regions. Most common drug preparations are in the [[sustained release]] forms. Vincamine is a monoterpenoid [[indole]] [[alkaloid]] found in the leaves of ''[[Vinca minor]]'', comprising about 25-65% of the indole alkaloids found in ''Vinca minor'' by weight. It can be synthesized from related alkaloids.<ref>{{ cite encyclopedia | title = Indole Alkaloids | encyclopedia = Ullmann's Encyclopedia of Industrial Chemistry | edition = Fifth | page = 393 | publisher = Wiley-VCH | year = 1985 | isbn = 3-527-20100-9 }}</ref> | '''Vincamine''' is a peripheral [[vasodilator]] that increases blood flow to the brain (sold under the trademark '''Oxybral SR''') . Generic drugs containing vincamine exist in specific regions. Most common drug preparations are in the [[sustained release]] forms. Vincamine is a monoterpenoid [[indole]] [[alkaloid]] found in the leaves of ''[[Vinca minor]]'', comprising about 25-65% of the indole alkaloids found in ''Vinca minor'' by weight. It can be synthesized from related alkaloids.<ref>{{ cite encyclopedia | title = Indole Alkaloids | encyclopedia = Ullmann's Encyclopedia of Industrial Chemistry | edition = Fifth | page = 393 | publisher = Wiley-VCH | year = 1985 | isbn = 3-527-20100-9 }}</ref> | ||
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==References== | ==References== | ||
{{reflist}} | {{reflist|2}} | ||
==External | ==External Links== | ||
* {{ cite web | url = http://www.mpbio.com/includes/msds/ansi/en/158295-EN-ANSI.pdf | format = pdf | title = Vincamine MSDS }} | * {{ cite web | url = http://www.mpbio.com/includes/msds/ansi/en/158295-EN-ANSI.pdf | format = pdf | title = Vincamine MSDS }} | ||
* {{ cite web | url = http://ntp-server.niehs.nih.gov/ntp/htdocs/Chem_Background/ExSumPdf/Vincamine.pdf | format = pdf | work = Summary of Data for Chemical Selection | title = Vincamine - 1617-90-9 | author = Chemical Selection Working Group | publisher = NIH - United States National Institutes of Health }} | * {{ cite web | url = http://ntp-server.niehs.nih.gov/ntp/htdocs/Chem_Background/ExSumPdf/Vincamine.pdf | format = pdf | work = Summary of Data for Chemical Selection | title = Vincamine - 1617-90-9 | author = Chemical Selection Working Group | publisher = NIH - United States National Institutes of Health }} | ||
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[[Category:Vasodilators]] | [[Category:Vasodilators]] | ||
[[Category:Cardiovascular Drugs]] | |||
[[Category:Drug]] | [[Category:Drug]] | ||
Latest revision as of 17:24, 20 August 2015
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| E number | {{#property:P628}} |
| ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
| Chemical and physical data | |
| Formula | C21H26N2O3 |
| Molar mass | 354.44 g/mol |
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Ongoing Trials on Vincamine at Clinical Trials.gov Clinical Trials on Vincamine at Google
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Vincamine is a peripheral vasodilator that increases blood flow to the brain (sold under the trademark Oxybral SR) . Generic drugs containing vincamine exist in specific regions. Most common drug preparations are in the sustained release forms. Vincamine is a monoterpenoid indole alkaloid found in the leaves of Vinca minor, comprising about 25-65% of the indole alkaloids found in Vinca minor by weight. It can be synthesized from related alkaloids.[1]
Vincamine is often used as a nootropic agent to combat the effects of aging, or in conjunction with other nootropics (such as piracetam) for a variety of purposes.
References
- ↑ "Indole Alkaloids". Ullmann's Encyclopedia of Industrial Chemistry (Fifth ed.). Wiley-VCH. 1985. p. 393. ISBN 3-527-20100-9.
External Links
- "Vincamine MSDS" (pdf).
- Chemical Selection Working Group. "Vincamine - 1617-90-9" (pdf). Summary of Data for Chemical Selection. NIH - United States National Institutes of Health.
See also
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