Pinacidil: Difference between revisions

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Latest revision as of 16:57, 20 August 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Pinacidil is a cyanoguanidine drug that opens ATP-sensitive potassium channels producing peripheral vasodilatation of arterioles.^[1] It reduces blood pressure and peripheral resistance and produces fluid retention.^[2]

↑ Gollasch M, Bychkov R, Ried C, Behrendt F, Scholze S, Luft FC, Haller H (1995). "Pinacidil relaxes porcine and human coronary arteries by activating ATP-dependent potassium channels in smooth muscle cells". J. Pharmacol. Exp. Ther. 275 (2): 681–92. PMID 7473155.
↑ Reynolds, James Blair; Martindale, William L. (1996). The extra pharmacopoeia (31st ed.). London: Royal Pharmaceutical Society. pp. 2739 pages. ISBN 0-85369-342-0.

Pinacidil at the US National Library of Medicine Medical Subject Headings (MeSH)

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