Yersinia pestis infection classification: Difference between revisions
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==Overview== | ==Overview== | ||
The classification of plague depends on the mode of infection and the clinical syndrome. Plague can be classified into bubonic plague, septicemic plague, or pneumonic plague. | The classification of plague depends on the mode of [[infection]] and the clinical [[syndrome]]. Plague can be classified into bubonic plague, septicemic plague, or pneumonic plague. | ||
==Classification== | ==Classification== | ||
===Bubonic Plague=== | ===Bubonic Plague=== | ||
Bubonic plague is transmitted by flea bite or direct contamination of an open skin lesion by plague-infected material. The infection spreads to the regional lymph nodes causing inflammation and swelling in one or several nodes (buboes).<ref name=WHObook>Plague Manual: Epidemiology, Distribution, Surveillance. World Health Organization. Communicable Disease Surveillance and Response | Bubonic plague is transmitted by flea bite or direct [[contamination]] of an open [[skin lesion]] by plague-infected material. The [[infection]] spreads to the regional [[lymph nodes]] causing [[inflammation]] and swelling in one or several nodes (buboes).<ref name=WHObook>Plague Manual: Epidemiology, Distribution, Surveillance. World Health Organization. Communicable Disease Surveillance and Response | ||
and Control. WHO/CDS/CSR/EDC/99.2 </ref> | and Control. WHO/CDS/CSR/EDC/99.2 </ref> | ||
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Pneumonic plague occurs in two distinct and epidemiologically significant forms.<ref name=WHObook>Plague Manual: Epidemiology, Distribution, Surveillance. World Health Organization. Communicable Disease Surveillance and Response | Pneumonic plague occurs in two distinct and epidemiologically significant forms.<ref name=WHObook>Plague Manual: Epidemiology, Distribution, Surveillance. World Health Organization. Communicable Disease Surveillance and Response | ||
and Control. WHO/CDS/CSR/EDC/99.2 </ref> | and Control. WHO/CDS/CSR/EDC/99.2 </ref> | ||
* Secondary plague pneumonia results from the hematogenous spread of ''Y. pestis'' to the [[lungs]]. | * Secondary plague [[pneumonia]] results from the hematogenous spread of ''[[Y. pestis]]'' to the [[lungs]]. | ||
* A primary pneumonic plague patient usually presents with an infectious [[pneumonitis]] upon the onset of symptoms. | * A primary pneumonic plague patient usually presents with an [[infectious]] [[pneumonitis]] upon the onset of [[symptoms]]. | ||
===Septicemic Plague=== | ===Septicemic Plague=== | ||
Septicemic plague can be primary or secondary to bubonic plague. Primary septicemic plague is a progressive, overwhelming bloodstream infection with ''Y. pestis'' in the apparent absence of a primary [[lymphadenopathy]].<ref name=WHObook>Plague Manual: Epidemiology, Distribution, Surveillance. World Health Organization. Communicable Disease Surveillance and Response | Septicemic plague can be primary or secondary to bubonic plague. Primary septicemic plague is a progressive, overwhelming [[bloodstream]] infection with ''[[Y. pestis]]'' in the apparent absence of a primary [[lymphadenopathy]].<ref name=WHObook>Plague Manual: Epidemiology, Distribution, Surveillance. World Health Organization. Communicable Disease Surveillance and Response | ||
and Control. WHO/CDS/CSR/EDC/99.2 </ref> | and Control. WHO/CDS/CSR/EDC/99.2 </ref> | ||
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* [[Abortive]] plague | * [[Abortive]] plague | ||
* Pestis minor | * Pestis minor | ||
* Asymptomatic plague | * [[Asymptomatic]] plague | ||
==References== | ==References== |
Revision as of 20:21, 25 July 2014
Yersinia pestis infection Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Assistant Editors-In-Chief: Esther Lee, M.A.; Rim Halaby, M.D. [2]; Alison Leibowitz [3]
Overview
The classification of plague depends on the mode of infection and the clinical syndrome. Plague can be classified into bubonic plague, septicemic plague, or pneumonic plague.
Classification
Bubonic Plague
Bubonic plague is transmitted by flea bite or direct contamination of an open skin lesion by plague-infected material. The infection spreads to the regional lymph nodes causing inflammation and swelling in one or several nodes (buboes).[1]
Pneumonic Plague
Pneumonic plague occurs in two distinct and epidemiologically significant forms.[1]
- Secondary plague pneumonia results from the hematogenous spread of Y. pestis to the lungs.
- A primary pneumonic plague patient usually presents with an infectious pneumonitis upon the onset of symptoms.
Septicemic Plague
Septicemic plague can be primary or secondary to bubonic plague. Primary septicemic plague is a progressive, overwhelming bloodstream infection with Y. pestis in the apparent absence of a primary lymphadenopathy.[1]
Other Types of Plagues
- Cellulocutaneous plague
- Meningeal plague
- Pharyngeal plague
- Abortive plague
- Pestis minor
- Asymptomatic plague