Hepatitis D risk factors: Difference between revisions
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== Risk Factors == | == Risk Factors == | ||
Since [[HDV]] requires the support of [[hepatitis B virus]] for its own replication, inoculation with [[HDV]] in the absence of [[HBV]] will not cause [[hepatitis D]]. Alone, the [[viral]] [[genome]] | Since [[HDV]] requires the support of [[hepatitis B virus]] for its own replication, inoculation with [[HDV]] in the absence of [[HBV]] will not cause [[hepatitis D]]. Alone, the [[viral]] [[genome]] replicates in a helper-independent manner, but the viral particles do not exit the cell.<ref name=WHO>{{cite web | title = Hepatitis D | url = http://www.who.int/csr/disease/hepatitis/HepatitisD_whocdscsrncs2001_1.pdf }}</ref><ref name=CDC>{{cite web | title = Hepatitis D (CDC) | url = http://www.cdc.gov/hepatitis/HDV/index.htm }}</ref> | ||
When in the presence of [[hepatitis B virus]], [[risk factor]]s for [[hepatitis D]] include: | When in the presence of [[hepatitis B virus]], [[risk factor]]s for [[hepatitis D]] include: | ||
* Using [[intravenous]] (IV) or injection drugs | * Using [[intravenous]] ([[IV]]) or injection drugs | ||
* Being infected while pregnant (the mother can pass the virus to the baby) | * Being infected while pregnant (the mother can pass the virus to the baby) | ||
* Carrying the [[hepatitis B virus]] | * Carrying the [[hepatitis B virus]] | ||
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* People exposed to unscreened [[blood]] or [[blood]] products | * People exposed to unscreened [[blood]] or [[blood]] products | ||
* [[Haemophilia|Haemophiliacs]] | * [[Haemophilia|Haemophiliacs]] | ||
*[[Hemodialysis]] patients | * [[Hemodialysis]] patients | ||
* Health care and public safety workers | * Health care and public safety workers | ||
* Individuals who are not infected with [[HBV]], and have not been [[vaccine|immunized]] against [[HBV]], are at risk of [[infection]] with [[HBV]] with simultaneous or subsequent infection with [[HDV]]. | * Individuals who are not infected with [[HBV]], and have not been [[vaccine|immunized]] against [[HBV]], are at risk of [[infection]] with [[HBV]] with simultaneous or subsequent infection with [[HDV]]. |
Revision as of 23:22, 5 August 2014
Hepatitis D |
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Hepatitis D risk factors On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: João André Alves Silva, M.D. [2] Jolanta Marszalek, M.D. [3]
Overview
Risk factors for hepatitis D, either in coinfection or superinfection with HBV, include: IV drug use; infection during pregnancy; sexual intercourse with infected persons; exposure to unscreened blood or blood products; hemodialysis patients; and healthcare and public service workers who deal with infected patients.[1][2]
Risk Factors
Since HDV requires the support of hepatitis B virus for its own replication, inoculation with HDV in the absence of HBV will not cause hepatitis D. Alone, the viral genome replicates in a helper-independent manner, but the viral particles do not exit the cell.[1][2]
When in the presence of hepatitis B virus, risk factors for hepatitis D include:
- Using intravenous (IV) or injection drugs
- Being infected while pregnant (the mother can pass the virus to the baby)
- Carrying the hepatitis B virus
- Men having sexual intercourse with other men
- Sexual intercourse with HDV infected persons
- Receiving many blood transfusions
- People exposed to unscreened blood or blood products
- Haemophiliacs
- Hemodialysis patients
- Health care and public safety workers
- Individuals who are not infected with HBV, and have not been immunized against HBV, are at risk of infection with HBV with simultaneous or subsequent infection with HDV.
References
- ↑ 1.0 1.1 "Hepatitis D" (PDF).
- ↑ 2.0 2.1 "Hepatitis D (CDC)".