Cutaneos Horn: Difference between revisions
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{{CMG}};{{AE} {{KS}} | {{CMG}}; {{AE}} {{KS}} | ||
==Overview== | ==Overview== | ||
'''Cutaneous horns''', also known by the Latin name '''''cornu cutaneum''''', are unusual [[keratin]]ous [[skin tumor]]s with the appearance of horns, or sometimes of wood or coral. Formally, this is a clinical diagnosis for a "conical projection above the surface of the skin."<ref name="Cutaneous horns: are these lesions as innocent as they seem to be?">{{cite journal |last1=Copcu |first1=Eray |last2=Sivrioglu |first2=Nazan |last3=Culhaci |first3=Nil |title=Cutaneous horns: are these lesions as innocent as they seem to be? |journal=World Journal of Surgical Oncology |volume=2 |page=18 |year=2004 |pmid=15176977 |pmc=421749 |doi=10.1186/1477-7819-2-18}}</ref> They are usually small and localized, but can, in very rare cases be much larger. Although often [[benign]], they can also be [[malignant]] or [[premalignant]].<ref name="A histopathological study of 643 cutaneous horns.">{{cite journal |last1=Yu |first1=R.C.H. |last2=Pryce |first2=D.W. |last3=MacFarlane |first3=A.W. |last4=Stewart |first4=T.W. |title=A histopathological study of 643 cutaneous horns |journal=British Journal of Dermatology |volume=124 |issue=5 |pages=449–52 |year=1991 |pmid=2039721 |doi=10.1111/j.1365-2133.1991.tb00624.x}}</ref> | '''Cutaneous horns''', also known by the Latin name '''''cornu cutaneum''''', are unusual [[keratin]]ous [[skin tumor]]s with the appearance of horns, or sometimes of wood or coral. Formally, this is a clinical diagnosis for a "conical projection above the surface of the skin."<ref name="Cutaneous horns: are these lesions as innocent as they seem to be?">{{cite journal |last1=Copcu |first1=Eray |last2=Sivrioglu |first2=Nazan |last3=Culhaci |first3=Nil |title=Cutaneous horns: are these lesions as innocent as they seem to be? |journal=World Journal of Surgical Oncology |volume=2 |page=18 |year=2004 |pmid=15176977 |pmc=421749 |doi=10.1186/1477-7819-2-18}}</ref> They are usually small and localized, but can, in very rare cases be much larger. Although often [[benign]], they can also be [[malignant]] or [[premalignant]].<ref name="A histopathological study of 643 cutaneous horns.">{{cite journal |last1=Yu |first1=R.C.H. |last2=Pryce |first2=D.W. |last3=MacFarlane |first3=A.W. |last4=Stewart |first4=T.W. |title=A histopathological study of 643 cutaneous horns |journal=British Journal of Dermatology |volume=124 |issue=5 |pages=449–52 |year=1991 |pmid=2039721 |doi=10.1111/j.1365-2133.1991.tb00624.x}}</ref> | ||
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Image:Cutaneos horn05.jpg|Cutaneos horn. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | Image:Cutaneos horn05.jpg|Cutaneos horn. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | ||
Image:Cutaneos horn07.jpg|Cutaneos horn. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | Image:Cutaneos horn07.jpg|Cutaneos horn. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | ||
</gallery> | </gallery> | ||
=====Extremities===== | =====Extremities===== | ||
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Image:Cutaneos horn09.jpg|Cutaneos horn. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | Image:Cutaneos horn09.jpg|Cutaneos horn. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | ||
Image:Cutaneos horn06.jpg|Cutaneos horn. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | Image:Cutaneos horn06.jpg|Cutaneos horn. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | ||
Image:Cutaneos horn10.jpg|Cutaneos horn. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | |||
</gallery> | </gallery> | ||
==Treatments== | ==Treatments== | ||
As the horn is composed of [[keratin]], the same material found in fingernails, the horn can usually be removed with a sterile razor. | As the horn is composed of [[keratin]], the same material found in fingernails, the horn can usually be removed with a sterile razor. |
Latest revision as of 18:05, 21 August 2014
Cutaneous horn | |
Classification and external resources | |
File:SkinTumors-P5280062.JPG | |
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Actinic keratosis with cutaneous horn | |
DiseasesDB | 31351 |
eMedicine | article/1056568 |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2]; Associate Editor(s)-in-Chief: Kiran Singh, M.D. [3]
Overview
Cutaneous horns, also known by the Latin name cornu cutaneum, are unusual keratinous skin tumors with the appearance of horns, or sometimes of wood or coral. Formally, this is a clinical diagnosis for a "conical projection above the surface of the skin."[1] They are usually small and localized, but can, in very rare cases be much larger. Although often benign, they can also be malignant or premalignant.[2]
Etiology
The cause of cutaneous horns is still unknown, but it is believed that exposure to radiation can trigger the condition. This is evidenced by a higher rate of cases occurring on the face and hands, areas that are often exposed to sunlight. Other cases have reported cutaneous horns arising from burn scars.[3] As with many other wart-like skin conditions, a link to the HPV virus family, especially the HPV-2 subtype has been suggested.[4]
Prominent cases
- Zhang Ruifang, aged 101 (living in Linlou Village, Henan province, China), has grown a cutaneous horn on her forehead, resembling what those who have examined her and her family call "Devil's Horns." Notably, this growth has expanded to reach a total of 6 centimeters in length. Another is forming on the opposite side of her forehead.[5]
- Huang Yuanfan, aged 84 (living in Ziyuan, China).[6]
- Madame Dimanche, called Widow Sunday, a French woman living in Paris in the early 19th century, grew, in six years from the age of 76, a 24.9 cm (9.8") horn from her forehead before it was successfully removed by French surgeon Br. Joseph Souberbeille (1754–1846). A wax model of her head is on display at the Mütter Museum, The College of Physicians of Philadelphia, US.[7]
Mortality/Morbidity
The lesion at the base of the keratin mound is benign in the majority of cases. Malignancy is present in up to 20% of cases, with squamous cell carcinoma being the most common type. The incidence of squamous cell carcinoma increases to 37% when the cutaneous horn is present on the penis.[8] Tenderness at the base of the lesion is often a clue to the presence of a possible underlying squamous cell carcinoma .
Diagnosis
Physical Examination
Skin
Face
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Cutaneos horn. Adapted from Dermatology Atlas.[9]
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Cutaneos horn. Adapted from Dermatology Atlas.[9]
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Cutaneos horn. Adapted from Dermatology Atlas.[9]
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Cutaneos horn. Adapted from Dermatology Atlas.[9]
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Cutaneos horn. Adapted from Dermatology Atlas.[9]
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Cutaneos horn. Adapted from Dermatology Atlas.[9]
Extremities
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Cutaneos horn. Adapted from Dermatology Atlas.[9]
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Cutaneos horn. Adapted from Dermatology Atlas.[9]
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Cutaneos horn. Adapted from Dermatology Atlas.[9]
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Cutaneos horn. Adapted from Dermatology Atlas.[9]
Treatments
As the horn is composed of keratin, the same material found in fingernails, the horn can usually be removed with a sterile razor.
However, the underlying condition will still need to be treated. Treatments vary, but they can include surgery, radiation therapy, and chemotherapy.
See also
References
- ↑ Copcu, Eray; Sivrioglu, Nazan; Culhaci, Nil (2004). "Cutaneous horns: are these lesions as innocent as they seem to be?". World Journal of Surgical Oncology. 2: 18. doi:10.1186/1477-7819-2-18. PMC 421749. PMID 15176977.
- ↑ Yu, R.C.H.; Pryce, D.W.; MacFarlane, A.W.; Stewart, T.W. (1991). "A histopathological study of 643 cutaneous horns". British Journal of Dermatology. 124 (5): 449–52. doi:10.1111/j.1365-2133.1991.tb00624.x. PMID 2039721.
- ↑ Nthumba, Peter M (2007). "Giant cutaneous horn in an African woman: a case report". Journal of Medical Case Reports. 1: 170. doi:10.1186/1752-1947-1-170. PMC 2225419. PMID 18053226.
- ↑ Wang, W; Wang, C; Xu, S; Chen, C; Tong, X; Liang, Y; Dong, X; Lei, Y; Zheng, X (2007). "Detection of HPV-2 and identification of novel mutations by whole genome sequencing from biopsies of two patients with multiple cutaneous horns". Journal of Clinical Virology. 39 (1): 34–42. doi:10.1016/j.jcv.2007.01.002. PMID 17368088.
- ↑ Writers, Staff. (2010-03-09) Chinese woman Zhang Ruifang, aged 101, grows 'devil' horn. Herald Sun. Retrieved on 2010-10-27.
- ↑ [1]. China's Huang Yuanfan Sprouts 3-Inch Horn From Head .
- ↑ The Mütter Museum. Corkscrew-balloon.com (2003-05-26). Retrieved on 2010-10-27.
- ↑ Solivan, GA; Smith, KJ; James, WD (1990). "squamous cell carcinoma". Journal of the American Academy of Dermatology. 23 (5 Pt 2): 969–72. doi:10.1016/0190-9622(90)70315-9. PMID 2172337.
- ↑ 9.00 9.01 9.02 9.03 9.04 9.05 9.06 9.07 9.08 9.09 "Dermatology Atlas".
External links
- Matthew Moore (2007-11-12). "Tree man 'who grew roots' may be cured". London: Daily Telegraph. Retrieved 2007-11-14.
- "Images of cutaneous horns". DermAtlas. Retrieved 2007-11-14.
- DiClaudio, Dennis (2006) "The Hypochondriac's Pocket Guide to Horrible Diseases You Probably Already Have", Bloomsbury Publishing, ISBN 978-1-59691-061-4