Enterovirus 68 future or investigational therapies: Difference between revisions
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(Created page with "__NOTOC__ {{CMG}}; {{AE}} {{AL}} {{Enterovirus 68}} ==Overview== ==Future or Investigational Therapies== ===Immune globulin=== * Studies in neonates with enterovirus infect...") |
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===Immune globulin=== | ===Immune globulin=== | ||
* Studies in neonates with enterovirus infection suggest a possible benefit of the use of immune globulin in the treatment of this viral infection | * Studies in neonates with enterovirus infection suggest a possible benefit of the use of immune globulin in the treatment of this viral infection<ref>{{Cite journal | ||
| author = [[Marc Tebruegge]] & [[Nigel Curtis]] | | author = [[Marc Tebruegge]] & [[Nigel Curtis]] | ||
| title = Enterovirus infections in neonates | | title = Enterovirus infections in neonates | ||
| Line 20: | Line 20: | ||
| pmid = 19303380 | | pmid = 19303380 | ||
}}</ref> | }}</ref> | ||
<ref>{{Cite journal | |||
| author = [[M. J. Abzug]], [[H. L. Keyserling]], [[M. L. Lee]], [[M. J. Levin]] & [[H. A. Rotbart]] | |||
| title = Neonatal enterovirus infection: virology, serology, and effects of intravenous immune globulin | |||
| journal = [[Clinical infectious diseases : an official publication of the Infectious Diseases Society of America]] | |||
| volume = 20 | |||
| issue = 5 | |||
| pages = 1201–1206 | |||
| year = 1995 | |||
| month = May | |||
| pmid = 7620000 | |||
}}</ref>, however, more studies need to be done do confirm the benefit of this treatment. | |||
*The development of IVIG with high levels of enterovirus antibody has shown benefit in ''in vitro'' and mouse models studies for enterovirus subtype 71, however, this has not been studied for subtype 68.<ref>{{Cite journal | *The development of IVIG with high levels of enterovirus antibody has shown benefit in ''in vitro'' and mouse models studies for enterovirus subtype 71, however, this has not been studied for subtype 68.<ref>{{Cite journal | ||
| author = [[Rui-Yuan Cao]], [[Jian-Feng Han]], [[Tao Jiang]], [[Xue Tian]], [[Man Yu]], [[Yong-Qiang Deng]], [[E.-De Qin]] & [[Cheng-Feng Qin]] | | author = [[Rui-Yuan Cao]], [[Jian-Feng Han]], [[Tao Jiang]], [[Xue Tian]], [[Man Yu]], [[Yong-Qiang Deng]], [[E.-De Qin]] & [[Cheng-Feng Qin]] | ||
Revision as of 17:44, 8 September 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]
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Overview
Future or Investigational Therapies
Immune globulin
- Studies in neonates with enterovirus infection suggest a possible benefit of the use of immune globulin in the treatment of this viral infection[1]
[2], however, more studies need to be done do confirm the benefit of this treatment.
- The development of IVIG with high levels of enterovirus antibody has shown benefit in in vitro and mouse models studies for enterovirus subtype 71, however, this has not been studied for subtype 68.[3]
Antiviral Medication
- Pleconaril
References
- ↑ Marc Tebruegge & Nigel Curtis (2009). "Enterovirus infections in neonates". Seminars in fetal & neonatal medicine. 14 (4): 222–227. doi:10.1016/j.siny.2009.02.002. PMID 19303380. Unknown parameter
|month=ignored (help) - ↑ M. J. Abzug, H. L. Keyserling, M. L. Lee, M. J. Levin & H. A. Rotbart (1995). "Neonatal enterovirus infection: virology, serology, and effects of intravenous immune globulin". Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 20 (5): 1201–1206. PMID 7620000. Unknown parameter
|month=ignored (help) - ↑ Rui-Yuan Cao, Jian-Feng Han, Tao Jiang, Xue Tian, Man Yu, Yong-Qiang Deng, E.-De Qin & Cheng-Feng Qin (2011). "In vitro and in vivo characterization of a new enterovirus type 71-specific human intravenous immunoglobulin manufactured from selected plasma donors". Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology. 51 (4): 246–249. doi:10.1016/j.jcv.2011.05.002. PMID 21641277. Unknown parameter
|month=ignored (help)