Drug-resistant tuberculosis medical therapy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]

Multiple Drug-Resistant MDR Tuberculosis

MDR-TB is defined as resistance to isoniazid and rifampicin, with or without resistance to other first-line drugs.

Extensively Drug-Resistant XDR Tuberculosis

XDR-TB is defined as resistance to at least isoniazid and rifampicin, and to any fluoroquinolone, and to any of the three second-line injectables (amikacin, capreomycin, and kanamycin).